Mechanisms of caspase activation and inhibition during apoptosis (Q27919623)

PubMed

PubMed publication ID

26 November 2016

1 reference

Europe PubMed Central

title

Mechanisms of caspase activation and inhibition during apoptosis (English)

1 reference

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

PubMed

PubMed publication ID

26 November 2016

0 references

1

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language of work or name

English

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publication date

March 2002

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1 reference

9

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issue

3

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page(s)

459-70

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cites work

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Human ICE/CED-3 protease nomenclature

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Cytokinesis, apoptosis and survivin: three for tango?

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Biochemical pathways of caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structural basis of caspase-7 inhibition by XIAP

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Plant pathogens and integrated defence responses to infection

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Insights into programmed cell death through structural biology

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structural biology. Controlling the caspases

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Understanding IAP function and regulation: a view from Drosophila

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The NOD: a signaling module that regulates apoptosis and host defense against pathogens

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Programmed cell death in animal development

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Livin, a novel inhibitor of apoptosis protein family member

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Control of apoptosis and mitotic spindle checkpoint by survivin

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

An exegesis of IAPs: salvation and surprises from BIR motifs

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Dimer formation drives the activation of the cell death protease caspase 9

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structural basis for the activation of human procaspase-7

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structural basis for the inhibition of caspase-3 by XIAP

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Caspase-9 and APAF-1 form an active holoenzyme

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Caspase activation: the induced-proximity model

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

A structural view of mitochondria-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Caspase-9 can be activated without proteolytic processing

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The atomic-resolution structure of human caspase-8, a key activator of apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structure and mechanism of interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Drosophila sickle is a novel grim-reaper cell death activator

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structural basis of IAP recognition by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Autoproteolytic activation of pro-caspases by oligomerization

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Apoptosis in the nervous system

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00482-3

7 January 2021