Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts (Q27851556)

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Pharmacologic Inhibition of Cyclin-Dependent Kinases 4 and 6 Arrests the Growth of Glioblastoma Multiforme Intracranial Xenografts

Language	Label	Description	Also known as
English	Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts	scientific article	Pharmacologic Inhibition of Cyclin-Dependent Kinases 4 and 6 Arrests the Growth of Glioblastoma Multiforme Intracranial Xenografts

Statements

scholarly article

1 reference

PubMed publication ID

13 November 2016

Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts (English)

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PubMed publication ID

13 November 2016

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Michael D Prados

6

object named as

Michael D Prados

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author name string

Karine Michaud

1

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David A Solomon

2

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Eric Oermann

3

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Jung-Sik Kim

4

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Wei-Zhu Zhong

5

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Tomoko Ozawa

7

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C David James

8

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Todd Waldman

9

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language of work or name

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publication date

15 April 2010

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Cancer Research

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70

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8

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3228-38

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PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

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20 March 2017

Cell cycle, CDKs and cancer: a changing paradigm

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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An integrated genomic analysis of human glioblastoma multiforme

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Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

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Cell cycle kinases as therapeutic targets for cancer

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Deletion of p16 and p15 genes in brain tumors

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Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma

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Sample type bias in the analysis of cancer genomes

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Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

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29 September 2017

Radiotherapy and radiosensitizers in the treatment of glioblastoma multiforme.

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29 September 2017

Influence of in vivo growth on human glioma cell line gene expression: convergent profiles under orthotopic conditions

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29 September 2017

Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.

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29 September 2017

Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts.

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29 September 2017

Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme

1 reference

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2 June 2018

Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.

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2 June 2018

Treatment of growing teratoma syndrome

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27 November 2018

A novel therapeutic combination using PD 0332991 and bortezomib: study in the 5T33MM myeloma model.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855904

27 November 2018

Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel

1 reference

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27 November 2018

A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6.

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27 November 2018

Flavopiridol induces apoptosis in glioma cell lines independent of retinoblastoma and p53 tumor suppressor pathway alterations by a caspase-independent pathway.

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Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855904

27 November 2018

Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855904

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Human glioblastomas with no alterations of the CDKN2A (p16INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene

1 reference

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27 November 2018

CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated.

1 reference

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1 reference

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CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20354191

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-09-4559

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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