Inhibition of the transforming activity of FLT3 internal tandem duplication mutants from AML patients by a tyrosine kinase inhibitor (Q27824787)

PubMed

PubMed publication ID

12357354

13 November 2016

title

Inhibition of the transforming activity of FLT3 internal tandem duplication mutants from AML patients by a tyrosine kinase inhibitor (English)

1 reference

PubMed

PubMed publication ID

13 November 2016

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K-F Tse

1

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J Allebach

2

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M Levis

3

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B D Smith

4

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F D Bohmer

5

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D Small

A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

6

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publication date

October 2002

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published in

Leukemia

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volume

16

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issue

10

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page(s)

2027-36

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cites work

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Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

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FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group

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