Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant (Q27724155)

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20 March 2020

title

Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant (English)

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20 March 2020

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3

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20 March 2020

Karl Gruber

4

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20 March 2020

author name string

Peter Augustin

1

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20 March 2020

Altijana Hromic

2

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20 March 2020

Peter Macheroux

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20 March 2020

language of work or name

English

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publication date

1 October 2016

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20 March 2020

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volume

283

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issue

19

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20 March 2020

page(s)

3587-3603

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Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction

20 March 2020

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Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate

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An Internal Reaction Chamber in Dimethylglycine Oxidase Provides Efficient Protection from Exposure to Toxic Formaldehyde

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Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase

20 March 2017

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Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency

20 March 2017

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Structure and analysis of the human dimethylglycine dehydrogenase gene

20 March 2017

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L-Pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases

20 March 2017

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Covalent flavinylation is essential for efficient redox catalysis in vanillyl-alcohol oxidase

20 March 2017

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Defect in dimethylglycine dehydrogenase, a new inborn error of metabolism: NMR spectroscopy study

20 March 2017

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Expression and Characterization of Two Pathogenic Mutations in Human Electron Transfer Flavoprotein

20 March 2017

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The effect of tetrahydrofolate on the reduction of electron transfer flavoprotein by sarcosine and dimethylglycine dehydrogenases

20 March 2017

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Identification of folate binding protein of mitochondria as dimethylglycine dehydrogenase

20 March 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 March 2017

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Enzymatic properties of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver

20 March 2017

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Over-expression in Escherichia coli, functional characterization and refolding of rat dimethylglycine dehydrogenase

20 March 2017

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Identification of the folate-binding proteins of rat liver mitochondria as dimethylglycine dehydrogenase and sarcosine dehydrogenase. Flavoprotein nature and enzymatic properties of the purified proteins

20 March 2017

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20 March 2017

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Dimethylglycine Deficiency and the Development of Diabetes.

29 September 2017

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Optimization of protein purification and characterization using Thermofluor screens

29 September 2017

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29 September 2017

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Molecular basis of dimethylglycine dehydrogenase deficiency associated with pathogenic variant H109R.

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2 June 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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An essential cysteine residue located in the vicinity of the FAD-binding site in short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria

27 November 2018

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12 December 2020

Identification of the folate-binding proteins of rat liver mitochondria as dimethylglycine dehydrogenase and sarcosine dehydrogenase. Purification and folate-binding characteristics

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12 December 2020

Alternate electron acceptors for medium-chain acyl-CoA dehydrogenase: use of ferricenium salts

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12 December 2020

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12 December 2020

Measurement of the equilibrium constant of the reaction between cytochrome c and cytochrome a

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12 December 2020

Mechanism of FAD reduction and role of active site residues His-225 and Tyr-259 in Arthrobacter globiformis dimethylglycine oxidase: analysis of mutant structure and catalytic function

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12 December 2020

Identifiers

DOI

10.1111/FEBS.13828

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27486859 AND SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

2 references

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20 March 2020

PubMed publication ID

27486859

2 references