Differing views of the role of selenium in thioredoxin reductase (Q27693988)

Erik L. Ruggles

series ordinal

2

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publication date

June 2011

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41

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issue

1

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page(s)

73-89

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Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Structural and Biochemical Studies Reveal Differences in the Catalytic Mechanisms of Mammalian and Drosophila melanogaster Thioredoxin Reductases †

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Nematode selenoproteome: the use of the selenocysteine insertion system to decode one codon in an animal genome?

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Crystal structure of selenosubtilisin at 2.0-A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

ATP-dependent reduction of cysteine–sulphinic acid by S. cerevisiae sulphiredoxin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Characterization of mammalian selenoproteomes.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Recent evidence for evolution of the genetic code

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Selenium in thioredoxin reductase: a mechanistic perspective

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Reduction of L-methionine selenoxide to seleno-L-methionine by endogenous thiols, ascorbic acid, or methimazole

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Eukaryotic selenoprotein synthesis: mechanistic insight incorporating new factors and new functions for old factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Synthesis of peptide substrates for mammalian thioredoxin reductase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Selenium in chemistry and biochemistry in comparison to sulfur

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Investigation of the C-terminal redox center of high-Mr thioredoxin reductase by protein engineering and semisynthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Characterization of mitochondrial thioredoxin reductase from C. elegans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Semisynthesis and characterization of mammalian thioredoxin reductase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Overexpression of enzymatically active human cytosolic and mitochondrial thioredoxin reductase in HEK-293 cells. Effect on cell growth and differentiation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Active sites of thioredoxin reductases: why selenoproteins?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Sulfur and selenium: the role of oxidation state in protein structure and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

29 September 2017

Vicinal disulfide turns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Trends in selenium biochemistry.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Evolutionarily different RNA motifs and RNA-protein complexes to achieve selenoprotein synthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Evolution of selenocysteine-containing proteins: significance of identification and functional characterization of selenoproteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Thioredoxin reductase two modes of catalysis have evolved

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Barriers to heterologous expression of a selenoprotein gene in bacteria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Escherichia coli genes whose products are involved in selenium metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Identification of a novel translation factor necessary for the incorporation of selenocysteine into protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Genetic code 1990. Outlook

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Selenocysteine: the 21st amino acid

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Kinetic studies on the peroxidase activity of selenosubtilisin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Coding from a distance: dissection of the mRNA determinants required for the incorporation of selenocysteine into protein

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Gene for a novel tRNA species that accepts L-serine and cotranslationally inserts selenocysteine.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Selenocysteine-containing thioredoxin reductase in C. elegans

19 June 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

A hypothesis on the catalytic mechanism of the selenoenzyme thioredoxin reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Selenocysteine in native chemical ligation and expressed protein ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Acid-base catalysis in the mechanism of thioredoxin reductase from Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Vicinal disulfide bridge conformers by experimental methods and by ab initio and DFT molecular computations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Mechanism of chalcone synthase. pKa of the catalytic cysteine and the role of the conserved histidine in a plant polyketide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Perturbations in the free energy and enthalpy of ionization of histidine-159 at the active site of papain as determined by fluorescence spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Mechanism of phosphatidylinositol-specific phospholipase C: origin of unusually high nonbridging thio effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

3'-(2,4-Dinitrobenzenesulfonyl)-2',7'-dimethylfluorescein as a fluorescent probe for selenols

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Selenium Speeds Reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Biomimetic studies on selenoenzymes: modeling the role of proximal histidines in thioredoxin reductases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

Nucleophilic Attack at Selenium in Diselenides and Selenosulfides. A Computational Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00726-010-0494-6

The mechanism of high Mr thioredoxin reductase from Drosophila melanogaster

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2935959

Reactivity and ionization of the active site cysteine residues of DsbA, a protein required for disulfide bond formation in vivo

27 November 2018

1 reference

12 December 2020

Knowing when not to stop: selenocysteine incorporation in eukaryotes

1 reference

12 December 2020

Reduction of methionine selenoxide to selenomethionine by glutathione

1 reference

12 December 2020

The twenty-first amino acid

1 reference

12 December 2020

The chemistry of flavins and flavoproteins. 3. The reaction of dihydrolipoic acid with flavins

1 reference

12 December 2020

Comparison of the chemical properties of selenocysteine and selenocystine with their sulfur analogs

1 reference

12 December 2020

Hypervalent organic derivatives of tellurium and selenium

1 reference

12 December 2020

Some aspects of bonding and structure in hypervalent selenium and tellurium chemistry

1 reference

12 December 2020

Effect of cysteine-25 on the ionization of histidine-159 in papain as determined by proton nuclear magnetic resonance spectroscopy. Evidence for a his-159--Cys-25 ion pair and its possible role in catalysis

1 reference

12 December 2020

1H NMR spectroscopic studies of selenosubtilisin

1 reference

12 December 2020

10.1007/S00726-010-0494-6

Identifiers

DOI

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Dimensions Publication ID

1037572731

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PubMed publication ID

20397034

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