Epidermal growth factor: a new therapeutic target in glomerular disease (Q27686898)

G. Bollee

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2

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C. Henique

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3

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P.-L. Tharaux

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4

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language of work or name

English

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publication date

April 2012

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Nephrology Dialysis Transplantation

published in

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volume

27

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issue

4

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page(s)

1297-304

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VEGF inhibition and renal thrombotic microangiopathy

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Podocytes contribute to the formation of glomerular crescents

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Role of intrinsic renal cells versus infiltrating cells in glomerular crescent formation

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Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

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Epidermal growth factor activates Na( /)H( ) exchanger in podocytes through a mechanism that involves Janus kinase and calmodulin

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Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia

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Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts.

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Heparin binding EGF is necessary for vasospastic response to endothelin.

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Epidermal growth factor receptor inhibition attenuates early kidney enlargement in experimental diabetes

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Inhibition of the epidermal growth factor receptor preserves podocytes and attenuates albuminuria in experimental diabetic nephropathy

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Evidence for glomerular actions of epidermal growth factor in the rat

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Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages

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Heparin-binding EGF-like growth factor contributes to reduced glomerular filtration rate during glomerulonephritis in rats

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Agonist-induced activation of matrix metalloproteinase-7 promotes vasoconstriction through the epidermal growth factor-receptor pathway

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Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice

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Identification of genes that regulate epithelial cell migration using an siRNA screening approach

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Podocytes Populate Cellular Crescents in a Murine Model of Inflammatory Glomerulonephritis

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Identifiers

DOI

10.1093/NDT/GFS030

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PubMed publication ID

22467748

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