The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal development (Q27681300)

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English	The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal development	scientific article

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scholarly article

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5 March 2020

The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal development (English)

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5 March 2020

structural biology

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crystal structure

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molecular motor

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Venkatasubramanian Ulaganathan

3

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5 March 2020

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5 March 2020

Frank Kozielski

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5 March 2020

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Marta Klejnot

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5 March 2020

Aditi Falnikar

2

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Peter W Baas

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24 December 2013

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5 March 2020

Acta Crystallographica Section D: Biological Crystallography

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Pt 1

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5 March 2020

123-133

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describes a project that uses

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Kinesin-5, a mitotic microtubule-associated motor protein, modulates neuronal migration

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A Nonmotor Microtubule Binding Site in Kinesin-5 Is Required for Filament Crosslinking and Sliding

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20 March 2017

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ATP hydrolysis in Eg5 kinesin involves a catalytic two-water mechanism

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Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference

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20 March 2017

Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis

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Human chromokinesin KIF4A functions in chromosome condensation and segregation

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The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK

1 reference

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20 March 2017

Structure of a fast kinesin: implications for ATPase mechanism and interactions with microtubules

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Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker

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20 March 2017

TPX2, A novel xenopus MAP involved in spindle pole organization

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20 March 2017

Interaction of a Golgi-associated kinesin-like protein with Rab6

1 reference

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20 March 2017

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

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20 March 2017

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation

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20 March 2017

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20 March 2017

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KAR3, a kinesin-related gene required for yeast nuclear fusion

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20 March 2017

Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality

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20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919264

7 April 2017

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9 May 2017

Kinesin-12 differentially affects spindle assembly depending on its microtubule substrate

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29 September 2017

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29 September 2017

Mechanisms of centrosome separation and bipolar spindle assembly

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Kinesin motor activation: microtubules pull the switches

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How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays

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29 September 2017

Kif15 cooperates with eg5 to promote bipolar spindle assembly

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Kinesin motor proteins as targets for cancer therapy

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29 September 2017

Kinesin's cover-neck bundle folds forward to generate force

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29 September 2017

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29 September 2017

KLP-18, a Klp2 kinesin, is required for assembly of acentrosomal meiotic spindles in Caenorhabditis elegans

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919264

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Expression of the mitotic motor protein Eg5 in postmitotic neurons: implications for neuronal development.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919264

2 June 2018

Purification of brain tubulin through two cycles of polymerization-depolymerization in a high-molarity buffer

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Force generation in kinesin hinges on cover-neck bundle formation

1 reference

https://api.crossref.org/works/10.1107/S1399004713028721

21 January 2018

Two kinesins from Arabidopsis, KatB and KatC, have a second microtubule-binding site in the tail domain.

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https://api.crossref.org/works/10.1107/S1399004713028721

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Characterization of microtubule binding domains in the Arabidopsis kinesin-like calmodulin binding protein

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27 November 2018

Mitotic regulation of microtubule cross-linking activity of CENP-E kinetochore protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/24419385

12 December 2020

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5 March 2020

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5 March 2020

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