Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor (Q27679516)

13

0 references

Douglas Adamoski

Douglas Adamoski

5

0 references

Rodrigo V Honorato

Rodrigo Vargas Honorato

7

0 references

Jefferson Bettini

Jefferson Bettini

André Luís Berteli Ambrósio

11

0 references

15

Andre Luis Berteli Ambrosio

0 references

author name string

Amanda Petrina Scotá Ferreira

1

0 references

Alexandre Cassago

2

0 references

Kaliandra de Almeida Gonçalves

3

0 references

Marília Meira Dias

4

0 references

Carolline Fernanda Rodrigues Ascenção

6

0 references

Juliana Ferreira de Oliveira

8

0 references

Igor Monteze Ferreira

9

0 references

Camila Fornezari

10

0 references

Paulo Sérgio Lopes Oliveira

12

0 references

Rodrigo Villares Portugal

14

0 references

Sandra Martha Gomes Dias

Journal of Biological Chemistry

16

0 references

language of work or name

English

0 references

publication date

27 September 2013

0 references

published in

0 references

volume

288

0 references

issue

39

0 references

page(s)

28009-20

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3784714/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Full-length human glutaminase in complex with an allosteric inhibitor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

MolProbity: all-atom structure validation for macromolecular crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Features and development of Coot

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Lysine acetylation targets protein complexes and co-regulates major cellular functions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Phasercrystallographic software

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Scaling and assessment of data quality

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Identification of novel interaction between ADAM17 (a disintegrin and metalloprotease 17) and thioredoxin-1.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Dibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Targeting cancer metabolism--aiming at a tumour's sweet-spot

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Targeting cancer metabolism: a therapeutic window opens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Targeting mitochondrial glutaminase activity inhibits oncogenic transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Expression of functional human glutaminase in baculovirus system: affinity purification, kinetic and molecular characterization.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Regulation of glutaminase activity and glutamine metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Correlation between activation and dimer formation of rat renal phosphate-dependent glutaminase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Inorganic phosphate as regulator of adenosine formation in isolated guinea pig hearts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Properties of rat renal phosphate-dependent glutaminase coupled to Sepharose. Evidence that dimerization is essential for activation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Ultrastructure of pig renal glutaminase. Evidence for conformational changes during polymer formation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Emergence and recovery response of phosphate metabolites and intracellular pH in intact Mytilus edulis as examined in situ by in vivo 31P-NMR.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784714

Bacterial expression, purification, and characterization of rat kidney-type mitochondrial glutaminase

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074/JBC.M113.501346

A phased translation function

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074/JBC.M113.501346

Regulation of renal ammoniagenesis. Purification and characterization of phosphate-dependent glutaminase from rat kidney

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23935106

12 December 2020

inferred from PubMed ID database lookup

Self-assembly of glutamic dehydrogenase into ordered superstructures: multichain tubes formed by association of single molecules

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23935106

12 December 2020

inferred from PubMed ID database lookup

Formation and ultrastructure of enzymically active polymers of pig renal glutaminase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23935106

12 December 2020