HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis (Q27679484)

14

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Rong Cao

object named as

Rong Cao

6

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Eric Oldfield

16

object named as

Eric Oldfield

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author name string

Yonghui Zhang

1

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Fu-Yang Lin

2

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Kai Li

3

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Wei Zhu

4

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Yi-Liang Liu

5

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Ran Pang

7

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Eunhae Lee

8

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Jordan Axelson

9

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Mary Hensler

10

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Ke Wang

11

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Katie J Molohon

12

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Yang Wang

ACS Medicinal Chemistry Letters

13

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publication date

3 April 2012

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published in

1 reference

Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)

Crossref

volume

3

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issue

5

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page(s)

402-406

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cites work

1 reference

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20 March 2017

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Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.

20 March 2017

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Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery

20 March 2017

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Retroviral intasome assembly and inhibition of DNA strand transfer

20 March 2017

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Inhibition of Staphyloxanthin Virulence Factor Biosynthesis in Staphylococcus aureus : In Vitro, in Vivo, and Crystallographic Results †

20 March 2017

1 reference

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A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence

20 March 2017

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Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases

20 March 2017

1 reference

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Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity

20 March 2017

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Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

20 March 2017

1 reference

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

20 March 2017

1 reference

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Terpene biosynthesis: modularity rules

20 March 2017

1 reference

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Targeting isoprenoid biosynthesis for drug discovery: bench to bedside

29 September 2017

1 reference

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Biophysical investigation of the mode of inhibition of tetramic acids, the allosteric inhibitors of undecaprenyl pyrophosphate synthase.

29 September 2017

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Repurposing libraries of eukaryotic protein kinase inhibitors for antibiotic discovery

29 September 2017

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Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors

29 September 2017

1 reference

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Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin

29 September 2017

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Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes

29 September 2017

1 reference

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Trinuclear metal clusters in catalysis by terpenoid synthases

29 September 2017

1 reference

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Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus

2 June 2018

1 reference

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Quinolone carboxylic acids as a novel monoketo acid class of human immunodeficiency virus type 1 integrase inhibitors

2 June 2018

1 reference

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Structural and theoretical studies of [6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)]-4-hydroxy-2-oxo-3-butenoïc acid as HIV-1 integrase inhibitor.

27 November 2018

1 reference

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Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): tetramic, tetronic acids and dihydropyridin-2-ones

27 November 2018

1 reference

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Synthesis of Z-5-carboxymethylene-1,3-dioxolan-4-ones: a better way

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22662288