A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors (Q27676650)

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English	A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors	scientific article

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A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors (English)

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1 reference

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inferred from title

16

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Ludovic Carlier

object named as

Ludovic Carlier

4

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Stefan H. Heinemann

object named as

Stefan H Heinemann

14

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13

object named as

Jan Tytgat

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author name string

Philippe Favreau

1

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Evelyne Benoit

2

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Henry G Hocking

3

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Dieter D' hoedt

5

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Enrico Leipold

6

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René Markgraf

7

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Sébastien Schlumberger

8

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Marco A Córdova

9

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Hubert Gaertner

10

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Marianne Paolini-Bertrand

11

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Oliver Hartley

12

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Daniel Bertrand

15

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Reto Stöcklin

17

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Jordi Molgó

18

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language of work or name

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publication date

July 2012

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British Journal of Pharmacology

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166

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5

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1654-68

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Using the deadly mu-conotoxins as probes of voltage-gated sodium channels

1 reference

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20 March 2017

Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419909

20 March 2017

Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419909

20 March 2017

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

1 reference

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20 March 2017

Three-dimensional solution structure of conotoxin psi-PIIIE, an acetylcholine gated ion channel antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419909

20 March 2017

Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419909

20 March 2017

A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors

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20 March 2017

Structure-activity relationships of mu-conotoxin GIIIA: structure determination of active and inactive sodium channel blocker peptides by NMR and simulated annealing calculations

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20 March 2017

Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA

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20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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20 March 2017

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

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20 March 2017

WHAT IF: a molecular modeling and drug design program

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20 March 2017

Stereochemical quality of protein structure coordinates

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20 March 2017

Diversity of the neurotoxic Conus peptides: a model for concerted pharmacological discovery

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20 March 2017

Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

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A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

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7 April 2017

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7 April 2017

Guide to Receptors and Channels (GRAC), 5th edition

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29 September 2017

A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain

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29 September 2017

Inhibition of the activation pathway of the T-type calcium channel Ca(V)3.1 by ProTxII.

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29 September 2017

Mu-conotoxins as leads in the development of new analgesics

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29 September 2017

Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor

1 reference

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29 September 2017

A subtle alternative splicing event of the Na(V)1.8 voltage-gated sodium channel is conserved in human, rat, and mouse.

1 reference

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29 September 2017

Conotoxins: natural product drug leads

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29 September 2017

Marine snail venoms: use and trends in receptor and channel neuropharmacology

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29 September 2017

Rapid sensitive analysis of cysteine rich peptide venom components.

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29 September 2017

Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion

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29 September 2017

Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus

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29 September 2017

Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419909

29 September 2017

High throughput screening of bradykinin-potentiating peptides in Bothrops moojeni snake venom using precursor ion mass spectrometry

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29 September 2017

Characterization of a novel psi-conotoxin from Conus parius Reeve

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29 September 2017

Conotoxin modulation of voltage-gated sodium channels

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29 September 2017

Spider toxins activate the capsaicin receptor to produce inflammatory pain.

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29 September 2017

Fourier transform mass spectrometry: a powerful tool for toxin analysis

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29 September 2017

Conotoxins and the posttranslational modification of secreted gene products

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29 September 2017

Ziconotide: neuronal calcium channel blocker for treating severe chronic pain

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29 September 2017

Conus venoms: a rich source of novel ion channel-targeted peptides

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29 September 2017

Differential blockade of rat alpha3beta4 and alpha7 neuronal nicotinic receptors by omega-conotoxin MVIIC, omega-conotoxin GVIA and diltiazem

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29 September 2017

Conus geographus toxins that discriminate between neuronal and muscle sodium channels.

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29 September 2017

Structurally minimized mu-conotoxin analogues as sodium channel blockers: implications for designing conopeptide-based therapeutics

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2 June 2018

Inhibition of sodium channel gating by trapping the domain II voltage sensor with protoxin II.

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2 June 2018

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2 June 2018

Distinction among neuronal subtypes of voltage-activated sodium channels by mu-conotoxin PIIIA.

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2 June 2018

Subunit stoichiometry of a mammalian K channel determined by construction of multimeric cDNAs.

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2 June 2018

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels

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21 January 2018

An automated system for intracellular and intranuclear injection

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A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.

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21 January 2018

Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels

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21 January 2018

Role of hydroxyprolines in the in vitro oxidative folding and biological activity of conotoxins.

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21 January 2018

Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone.

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21 January 2018

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21 January 2018

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21 January 2018

Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels

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21 January 2018

Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons

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https://api.crossref.org/works/10.1111/J.1476-5381.2012.01837.X

21 January 2018

Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels

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21 January 2018

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

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21 January 2018

New sodium channel-blocking conotoxins also affect calcium currents in Lymnaea neurons

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https://pubmed.ncbi.nlm.nih.gov/22229737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A noncompetitive peptide inhibitor of the nicotinic acetylcholine receptor from Conus purpurascens venom

1 reference

https://pubmed.ncbi.nlm.nih.gov/22229737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conus peptides as probes for ion channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22229737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of cloned skeletal muscle sodium channels by the scorpion toxins Lqh II, Lqh III, and Lqh alphaIT

1 reference

https://pubmed.ncbi.nlm.nih.gov/22229737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution structure of mu-conotoxin GIIIA analysed by 2D-NMR and distance geometry calculations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22229737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active site of mu-conotoxin GIIIA, a peptide blocker of muscle sodium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22229737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2012.01837.X

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