RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover (Q27676229)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23389036 AND SRC:MED&resulttype=core&format=json

23 February 2020

title

RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover (English)

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23 February 2020

0 references

1

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23 February 2020

Alexandre R Gingras

6

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23 February 2020

Gordon Roberts

8

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23 February 2020

Christoph Ballestrem

9

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23 February 2020

author name string

Thomas Zacharchenko

2

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23 February 2020

Neil Bate

3

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23 February 2020

Ricky Tsang

4

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23 February 2020

Fiona Hey

5

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23 February 2020

Paul R Elliott

7

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23 February 2020

David R Critchley

10

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23 February 2020

Igor L Barsukov

11

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23 February 2020

language of work or name

English

0 references

publication date

6 February 2013

1 reference

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Journal of Biological Chemistry

23 February 2020

published in

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23 February 2020

volume

288

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23 February 2020

issue

12

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23 February 2020

page(s)

8238-8249

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Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector

23 February 2020

cites work

1 reference

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Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics

20 March 2017

1 reference

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The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

20 March 2017

1 reference

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Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin

20 March 2017

1 reference

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The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site

20 March 2017

1 reference

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Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation

20 March 2017

1 reference

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The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.

20 March 2017

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Ena/VASP: towards resolving a pointed controversy at the barbed end

20 March 2017

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The Structure of an Interdomain Complex That Regulates Talin Activity

20 March 2017

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Structural Determinants of Integrin Binding to the Talin Rod

20 March 2017

1 reference

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RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

20 March 2017

1 reference

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Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin

20 March 2017

1 reference

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The structure of the C-terminal actin-binding domain of talin

20 March 2017

1 reference

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Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

20 March 2017

1 reference

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Vinculin activation by talin through helical bundle conversion

20 March 2017

1 reference

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Scaling and assessment of data quality

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK)

20 March 2017

1 reference

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Nanoscale architecture of integrin-based cell adhesions

20 March 2017

1 reference

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Structural and dynamic characterization of a vinculin binding site in the talin rod

20 March 2017

1 reference

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RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

20 March 2017

1 reference

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Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin

20 March 2017

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Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

20 March 2017

1 reference

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Stretching single talin rod molecules activates vinculin binding

20 March 2017

1 reference

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Subcellular localization of talin is regulated by inter-domain interactions

7 April 2017

1 reference

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The C terminus of talin links integrins to cell cycle progression.

29 September 2017

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The tail of integrin activation

29 September 2017

1 reference

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Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.

29 September 2017

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29 September 2017

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29 September 2017

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New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering

29 September 2017

1 reference

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Structural and biophysical properties of the integrin-associated cytoskeletal protein talin

29 September 2017

1 reference

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Biochemical and structural properties of the integrin-associated cytoskeletal protein talin

29 September 2017

1 reference

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Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails

29 September 2017

1 reference

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Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3

29 September 2017

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How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism

29 September 2017

1 reference

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Vinculin controls focal adhesion formation by direct interactions with talin and actin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605642

The structure and regulation of vinculin.

29 September 2017

1 reference

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Molecular diversity of cell-matrix adhesions.

29 September 2017

1 reference

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Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605642

Structural basis for the autoinhibition of talin in regulating integrin activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605642

A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605642

NMR assignment of the C-terminal actin-binding domain of talin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605642

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins

27 November 2018

1 reference

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Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605642

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605642

Role of vinculin in regulating focal adhesion turnover

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23389036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Analysis of Repeated Motifs in the Talin Rod

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23389036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.438119

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23389036 AND SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23389036 AND SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

23389036

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23389036 AND SRC:MED&resulttype=core&format=json