HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase (Q27675416)

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Michelle Webb

15

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Evangelos Christodoulou

Evangelos Christodoulou

6

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David Goldstone

David C Goldstone

1

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Gillian I. Rice

Gillian I Rice

5

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Jonathan P. Stoye

Jonathan P Stoye

12

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Yanick J. Crow

Yanick J Crow

13

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Geoff Kelly

8

Geoff Kelly

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Luiz Pedro S de Carvalho

Luiz Pedro S de Carvalho

11

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author name string

Valerie Ennis-Adeniran

2

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Joseph J Hedden

3

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Harriet C T Groom

4

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Philip A Walker

7

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Lesley F Haire

9

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Melvyn W Yap

10

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Ian A Taylor

Trex1 prevents cell-intrinsic initiation of autoimmunity

14

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language of work or name

English

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publication date

6 November 2011

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published in

Nature

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volume

480

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issue

7377

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page(s)

379-82

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cites work

1 reference

12 December 2020

The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection

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12 December 2020

Excision of misincorporated ribonucleotides in DNA by RNase H (type 2) and FEN-1 in cell-free extracts

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The purification and properties of deoxyguanosine triphosphate triphosphohydrolase from Escherichia coli

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12 December 2020

Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

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12 December 2020

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

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12 December 2020

Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease

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12 December 2020

Biochemical properties of mammalian TREX1 and its association with DNA replication and inherited inflammatory disease

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A novel fluorescence-based assay for the rapid detection and quantification of cellular deoxyribonucleoside triphosphates.

1 reference

12 December 2020

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

1 reference

12 December 2020

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

1 reference

12 December 2020

Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection

1 reference

12 December 2020

The HD domain defines a new superfamily of metal-dependent phosphohydrolases

1 reference

12 December 2020

Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation.

1 reference

12 December 2020

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

1 reference

12 December 2020

Automated structure solution with the PHENIX suite

1 reference

12 December 2020

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

1 reference

12 December 2020

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

1 reference

12 December 2020

Ribonucleoside triphosphates as substrate of human immunodeficiency virus type 1 reverse transcriptase in human macrophages

1 reference

12 December 2020

Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition

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12 December 2020

A cellular restriction dictates the permissivity of nondividing monocytes/macrophages to lentivirus and gammaretrovirus infection

1 reference

12 December 2020

Virus infection switches TLR-3-positive human neurons to become strong producers of beta interferon

1 reference

12 December 2020

Reduced dNTP binding affinity of 3TC-resistant M184I HIV-1 reverse transcriptase variants responsible for viral infection failure in macrophage

1 reference

12 December 2020

Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase

1 reference

12 December 2020

Structure of dNTP-inducible dNTP triphosphohydrolase: insight into broad specificity for dNTPs and triphosphohydrolase-type hydrolysis

1 reference

12 December 2020

Identification of human homologue of mouse IFN-gamma induced protein from human dendritic cells

1 reference

12 December 2020

SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells

1 reference

12 December 2020

Biochemical characterization of TT1383 from Thermus thermophilus identifies a novel dNTP triphosphohydrolase activity stimulated by dATP and dTTP.

1 reference

12 December 2020

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

Crossref

https://api.crossref.org/works/10.1038/NATURE10623

7 January 2021