The Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active Site (Q27675214)

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15 January 2020

title

The miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site (English)

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15 January 2020

3

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15 January 2020

Sylvie Doublié

series ordinal

4

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15 January 2020

author name string

Karl E Zahn

series ordinal

1

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15 January 2020

April Averill

series ordinal

2

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language of work or name

English

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publication date

3 November 2011

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15 January 2020

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volume

50

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issue

47

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page(s)

10350-10358

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Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP To Be Inserted opposite 7,8-Dihydro-8-oxoguanine,

15 January 2020

cites work

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Crystal Structure of a Replicative DNA Polymerase Bound to the Oxidized Guanine Lesion Guanidinohydantoin ,

20 March 2017

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Structures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during Misincorporation

20 March 2017

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Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals.

20 March 2017

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Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines

20 March 2017

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20 March 2017

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Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69

20 March 2017

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Normal oxidative damage to mitochondrial and nuclear DNA is extensive

20 March 2017

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Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family

20 March 2017

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Structures of mismatch replication errors observed in a DNA polymerase

20 March 2017

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20 March 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects

29 September 2017

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Oxidized, deaminated cytosines are a source of C → T transitions in vivo

29 September 2017

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Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.

29 September 2017

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29 September 2017

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29 September 2017

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12 December 2020

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[26] Screening for heavy-atom derivatives and obtaining accurate isomorphous differences.

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Identifiers

DOI

10.1021/BI201219S

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22026756 AND SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

2 references

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15 January 2020

PubMed publication ID

22026756

2 references