Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase (Q27666605)

Antonio L Llamas-Saiz

4

0 references

Mark J van Raaij

Mark J van Raaij

6

0 references

Lorena Tizón

2

Lorena Tizón

0 references

Heather M Lamb

7

Heather Lamb

0 references

Alastair R Hawkins

8

Alastair R Hawkins

0 references

Gavin C Fox

5

Concepcion Gonzalez-bello

Gavin C Fox

0 references

11

Concepción González-Bello

0 references

author name string

Sonia Paz

1

0 references

José M Otero

3

0 references

Luis Castedo

Bacterial persistence: some new insights into an old phenomenon

10

0 references

publication date

7 February 2011

0 references

published in

ChemMedChem

0 references

volume

6

0 references

issue

2

0 references

page(s)

266-72

0 references

cites work

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Antibiotics for emerging pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

The shikimate pathway--a metabolic tree with many branches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

21 January 2018

THE SHIKIMATE PATHWAY

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

DEG 5.0, a database of essential genes in both prokaryotes and eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

DEG: a database of essential genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Progress in type II dehydroquinase inhibitors: from concept to practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

(1R,4S,5R)-3-Fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid: the fluoro analogue of the enolate intermediate in the reaction catalyzed by type II dehydroquinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Parallel solid-phase synthesis and evaluation of inhibitors of Streptomyces coelicolor type II dehydroquinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Structure-based design, synthesis, and biological evaluation of inhibitors of Mycobacterium tuberculosis type II dehydroquinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Competitive inhibitors of Helicobacter pylori type II dehydroquinase: synthesis, biological evaluation, and NMR studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Evidence from kinetic isotope studies for an enolate intermediate in the mechanism of type II dehydroquinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Understanding the key factors that control the inhibition of type II dehydroquinase by (2R)-2-benzyl-3-dehydroquinic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

2-substituted-3-dehydroquinic acids as potent competitive inhibitors of type II dehydroquinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Crystal structures of Helicobacter pylori type II dehydroquinase inhibitor complexes: new directions for inhibitor design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Scaling and assessment of data quality

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Interactions with aromatic rings in chemical and biological recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Localization of the Active Site of Type II Dehydroquinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

Selective Inhibition of Type II Dehydroquinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

7 January 2021

Nanomolar Competitive Inhibitors ofMycobacterium tuberculosis andStreptomyces coelicolor Type II Dehydroquinase

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

7 January 2021

Nanomolar inhibition of type II dehydroquinase based on the enolate reaction mechanism

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

7 January 2021

Rational design, synthesis, and evaluation of nanomolar type II dehydroquinase inhibitors

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

7 January 2021

Use of Lawesson's reagent in organic syntheses

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

7 January 2021

The use of electrospray mass spectrometry to identify an essential arginine residue in type II dehydroquinases

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

7 January 2021

Free R value: cross-validation in crystallography

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

7 January 2021

Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two thrombin-inhibitor complexes

1 reference

https://api.crossref.org/works/10.1002/CMDC.201000343

7 January 2021