The mechanism and control of DNA transfer by the conjugative relaxase of resistance plasmid pCU1 (Q27661390)

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1 February 2020

title

The mechanism and control of DNA transfer by the conjugative relaxase of resistance plasmid pCU1 (English)

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4

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5

Matthew R Redinbo

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author name string

Rebekah Potts Nash

series ordinal

1

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1 February 2020

Sohrab Habibi

series ordinal

2

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1 February 2020

Yuan Cheng

series ordinal

3

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language of work or name

English

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publication date

6 May 2010

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published in

Nucleic Acids Research

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volume

38

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issue

17

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page(s)

5929-8633

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Creative Commons Attribution-NonCommercial 2.5 Generic

1 February 2020

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Conjugative transfer can be inhibited by blocking relaxase activity within recipient cells with intrabodies.

29 September 2017

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29 September 2017

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Unveiling the molecular mechanism of a conjugative relaxase: The structure of TrwC complexed with a 27-mer DNA comprising the recognition hairpin and the cleavage site.

29 September 2017

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Unsaturated fatty acids are inhibitors of bacterial conjugation

29 September 2017

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Inter- and intramolecular determinants of the specificity of single-stranded DNA binding and cleavage by the F factor relaxase.

29 September 2017

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The F-plasmid TraI protein contains three functional domains required for conjugative DNA strand transfer

29 September 2017

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Swapping single-stranded DNA sequence specificities of relaxases from conjugative plasmids F and R100

29 September 2017

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Relaxed specificity of the R1162 nickase: a model for evolution of a system for conjugative mobilization of plasmids

29 September 2017

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29 September 2017

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29 September 2017

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Recognition of oriT for DNA processing at termination of a round of conjugal transfer

29 September 2017

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29 September 2017

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29 September 2017

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Two active-site tyrosyl residues of protein TrwC act sequentially at the origin of transfer during plasmid R388 conjugation

29 September 2017

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Genetic analysis of the mobilization and leading regions of the IncN plasmids pKM101 and pCU1

29 September 2017

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Localization of the nic site of IncN conjugative plasmid pCU1 through formation of a hybrid oriT

29 September 2017

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Mechanisms of initiation and termination reactions in conjugative DNA processing. Independence of tight substrate binding and catalytic activity of relaxase (TraI) of IncPalpha plasmid RP4.

29 September 2017

1 reference

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Characterization of the reaction product of the oriT nicking reaction catalyzed by Escherichia coli DNA helicase I.

29 September 2017

1 reference

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Relaxase (TraI) of IncP alpha plasmid RP4 catalyzes a site-specific cleaving-joining reaction of single-stranded DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Specific binding of MobA, a plasmid-encoded protein involved in the initiation and termination of conjugal DNA transfer, to single-stranded oriT DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Essential motifs of relaxase (TraI) and TraG proteins involved in conjugative transfer of plasmid RP4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

DNA processing reactions in bacterial conjugation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Processing of plasmid DNA during bacterial conjugation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

The oriT region of the conjugative transfer system of plasmid pCU1 and specificity between it and the mob region of other N tra plasmids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Effect of divalent ions on the minimal relaxase domain of MobA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Analysis of DNA processing reactions in bacterial conjugation by using suicide oligonucleotides.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Nicking by transesterification: the reaction catalysed by a relaxase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Functional domains in protein TrwC of plasmid R388: dissected DNA strand transferase and DNA helicase activities reconstitute protein function.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Structural and functional analysis of the origin of conjugal transfer of the broad-host-range IncW plasmid R388 and comparison with the related IncN plasmid R46.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

The r1162 mob proteins can promote conjugative transfer from cryptic origins in the bacterial chromosome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Roles of active site residues and the HUH motif of the F plasmid TraI relaxase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

An engineered multidomain bactericidal peptide as a model for targeted antibiotics against specific bacteria

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Purification and biochemical characterization of TrwC, the helicase involved in plasmid R388 conjugal DNA transfer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Nicking activity of TrwC directed against the origin of transfer of the IncW plasmid R388.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

Stepwise assembly of a relaxosome at the F plasmid origin of transfer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

The traY gene product and integration host factor stimulate Escherichia coli DNA helicase I-catalyzed nicking at the F plasmid oriT.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943615

A new filamentous bacteriophage with sex-factor specificity

27 November 2018

1 reference

12 December 2020

F plasmid conjugative DNA transfer: the TraI helicase activity is essential for DNA strand transfer

1 reference

12 December 2020

Winning the asymmetric war: new strategies for combating antibacterial resistance

1 reference

12 December 2020

Escherichia coli DNA helicase I catalyzes a sequence-specific cleavage/ligation reaction at the F plasmid origin of transfer

1 reference

12 December 2020

Physical and genetic organization of the IncN-group plasmid pCU1

1 reference

12 December 2020

DNA binding properties of protein TrwA, a possible structural variant of the Arc repressor superfamily

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKQ303

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20448025 AND SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20448025 AND SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

20448025

2 references