Glycal Formation in Crystals of Uridine Phosphorylase , (Q27660422)

1

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Seán E O'Leary

2

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Kanagalaghatta Rajashankar

3

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Weiming Bu

4

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Angela Toms

5

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Ethan C Settembre

6

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Jennie M Sanders

7

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Tadhg P Begley

Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy

8

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language of work or name

English

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publication date

27 April 2010

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published in

Biochemistry

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volume

49

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issue

16

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page(s)

3499-509

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cites work

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Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues

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The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

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Influenza B virus neuraminidase can synthesize its own inhibitor

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Atomic structure at 2.5 A resolution of uridine phosphorylase from E. coli as refined in the monoclinic crystal lattice

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Substructure solution with SHELXD

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Protein structure comparison by alignment of distance matrices

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Three-dimensional structure of human erythrocytic purine nucleoside phosphorylase at 3.2 A resolution

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Structural analyses reveal two distinct families of nucleoside phosphorylases

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One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

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xdlMAPMAN and xdlDATAMAN - programs for reformatting, analysis and manipulation of biomacromolecular electron-density maps and reflection data sets

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Preliminary investigation of the three-dimensional structure of Salmonella typhimurium uridine phosphorylase in the crystalline state

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Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines

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Crystal structures of Escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium

27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20364833

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20364833

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cytoplsmic uridine phosphorylase of rat liver. Characterization and kinetics

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20364833

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI902073B

1 reference

1 reference

1 reference

PubMed publication ID

20364833

1 reference