Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases (Q27657740)

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9 February 2020

title

Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases (English)

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0 references

6

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Steven N. Seyedin

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Helen Walden

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J Wade Harper

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author name string

Min Zhuang

1

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9 February 2020

Matthew F Calabrese

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Jiang Liu

3

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M Brett Waddell

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Amanda Nourse

5

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Darcie J Miller

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David M Duda

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Timothy Hoggard

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Kevin P White

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Brenda A Schulman

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publication date

1 October 2009

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9 February 2020

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volume

36

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issue

1

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page(s)

39-50

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Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

9 February 2020

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20 March 2017

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20 March 2017

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Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase

20 March 2017

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Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

20 March 2017

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Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

20 March 2017

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Distinct molecular mechanism for initiating TRAF6 signalling

20 March 2017

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

20 March 2017

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Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling

20 March 2017

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Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

20 March 2017

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Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

20 March 2017

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Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

20 March 2017

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

20 March 2017

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The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila

20 March 2017

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Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

20 March 2017

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A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway

20 March 2017

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20 March 2017

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7 April 2017

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The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

7 April 2017

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Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

7 April 2017

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Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

7 April 2017

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Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway

7 April 2017

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Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer.

7 April 2017

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Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

29 September 2017

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Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism

29 September 2017

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Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail

29 September 2017

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Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases

29 September 2017

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Fbw7/hCDC4 dimerization regulates its substrate interactions

29 September 2017

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Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells--evidence for cullin dimerization

29 September 2017

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Structure, function and evolution of multidomain proteins

29 September 2017

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Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.

29 September 2017

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BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

29 September 2017

1 reference

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The SCF ubiquitin ligase: an extended look

29 September 2017

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Genetic and molecular characterization of the caenorhabditis elegans gene, mel-26, a postmeiotic negative regulator of mei-1, a meiotic-specific spindle component.

29 September 2017

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A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

29 September 2017

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Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus

27 November 2018

1 reference

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BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase.

27 November 2018

1 reference

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Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases

27 November 2018

1 reference

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The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.

27 November 2018

1 reference

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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

27 November 2018

1 reference

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Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19818708

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19818708

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

BTB proteins as henchmen of Cul3-based ubiquitin ligases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19818708

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2009.09.022

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19818708 AND SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19818708 AND SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

19818708

2 references