Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors (Q27643993)

51

0 references

Stephanie Moquin

22

0 references

Pamela J. Bjorkman

48

0 references

An-Suei Yang

An-Suei Yang

32

0 references

Tongqing Zhou

Tongqing Zhou

1

0 references

Myron S. Cohen

39

Myron S Cohen

0 references

Michel C. Nussenzweig

50

Michel C Nussenzweig

0 references

John R. Mascola

52

John R Mascola

0 references

James C Mullikin

34

James C Mullikin

0 references

Barton Haynes

40

Barton F Haynes

0 references

Quentin J Sattentau

45

Quentin J Sattentau

0 references

Cinque Soto

9

Cinque Soto

0 references

Peter D. Kwong

53

Peter D Kwong

0 references

Dennis R. Burton

37

Dennis R Burton

0 references

Nicole Doria-Rose

6

Nicole A Doria-Rose

0 references

M Gordon Joyce

7

M Gordon Joyce

0 references

Ivelin S. Georgiev

29

Ivelin S Georgiev

0 references

Nancy S Longo

13

Nancy S Longo

0 references

Mark K. Louder

14

Mark K Louder

0 references

Priyamvada Acharya

4

Priyamvada Acharya

0 references

Krisha McKee

15

Krisha McKee

0 references

Sijy O'Dell

16

Sijy O'Dell

0 references

Zhongjia Yang

19

Zhongjia Yang

0 references

Timothy S Luongo

21

Timothy S Luongo

0 references

Yongping Yang

24

Yongping Yang

0 references

Marie Pancera

27

Marie Pancera

0 references

Wayne C Koff

38

Wayne C Koff

0 references

Leonidas Stamatatos

36

Leonidas Stamatatos

0 references

Aliaksandr Druz

20

Aliaksandr Druz

0 references

Robin A Weiss

46

Robin A Weiss

0 references

Stephen D Schmidt

17

Stephen D Schmidt

0 references

Rebecca M Lynch

2

Rebecca M Lynch

0 references

Sanjay R Srivatsan

23

Sanjay Srivatsan

0 references

Daniel Lingwood

8

Daniel Lingwood

0 references

Michael J. Ernandes

11

Michael J Ernandes

0 references

Lillian Tran

18

Lillian Tran

0 references

Tatsiana Kirys

28

Tatsiana Kirys

0 references

Tatyana S Gindin

30

Tatyana Gindin

0 references

Joseph P Casazza

41

Joseph P Casazza

0 references

Matthew D Gray

35

Matthew D Gray

0 references

Johannes F Scheid

49

Johannes F Scheid

0 references

Baoshan Zhang

25

Baoshan Zhang

0 references

Robert Bailer

10

Robert T Bailer

0 references

Anqi Zheng

26

Anqi Zheng

0 references

Mark Connors

42

Mark Connors

0 references

Davide Corti

43

Davide Corti

0 references

author name string

Lei Chen

3

0 references

Xueling Wu

5

0 references

Rui Kong

12

0 references

Hung-Pin Peng

31

0 references

Anthony P West

Structural insights on the role of antibodies in HIV-1 vaccine and therapy

47

0 references

language of work or name

English

0 references

publication date

4 June 2015

0 references

published in

Cell

0 references

volume

161

0 references

issue

6

0 references

page(s)

1280-92

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

A new clustering of antibody CDR loop conformations

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Structural definition of a conserved neutralization epitope on HIV-1 gp120

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Phasercrystallographic software

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

The development of CD4 binding site antibodies during HIV-1 infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

A method for identification of HIV gp140 binding memory B cells in human blood

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Measuring HIV neutralization in a luciferase reporter gene assay

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Free energy determinants of tertiary structure and the evaluation of protein models.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Biological characterization of a simian immunodeficiency virus-like retrovirus (HTLV-IV): evidence for CD4-associated molecules required for infection.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Crystal structure of an HIV-binding recombinant fragment of human CD4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

HIV infection of primate lymphocytes and conservation of the CD4 receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683157

10.1016/J.CELL.2015.05.007

2 June 2018

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

26004070

1 reference