Structural basis for the NAD-dependent deacetylase mechanism of Sir2 (Q27639274)

5

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author name string

Jeong-Ho Chang

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Hyun-Chul Kim

2

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Kwang-Yeon Hwang

3

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Joon-Won Lee

4

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Yunje Cho

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

13 September 2002

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published in

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volume

277

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issue

37

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page(s)

34489-98

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cites work

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

A phylogenetically conserved NAD -dependent protein deacetylase activity in the Sir2 protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Common themes in mechanisms of gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

An unusual form of transcriptional silencing in yeast ribosomal DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Vicious circles: a mechanism for yeast aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Crystal structure of a SIR2 homolog-NAD complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD -dependent deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Structure of the histone deacetylase SIRT2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Chemistry of gene silencing: the mechanism of NAD -dependent deacetylation reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD -dependent histone/protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Archaeoglobus fulgidus gen. nov., sp. nov.: a New Taxon of Extremely Thermophilic Archaebacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200

Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M205460200