Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant (Q27638329)

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8 December 2019

title

Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant (English)

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8 December 2019

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2

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author name string

Jimmy Lindberg

1

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8 December 2019

Seved Löwgren

3

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8 December 2019

Hans O Andersson

4

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8 December 2019

Christer Sahlberg

5

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8 December 2019

Rolf Noréen

6

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8 December 2019

Kerstin Fridborg

7

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8 December 2019

Hong Zhang

8

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8 December 2019

Torsten Unge

9

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language of work or name

English

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publication date

1 March 2002

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8 December 2019

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8 December 2019

volume

269

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issue

6

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page(s)

1670-1677

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Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

8 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Delavirdine susceptibilities and associated reverse transcriptase mutations in human immunodeficiency virus type 1 isolates from patients in a phase I/II trial of delavirdine monotherapy (ACTG 260)

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

L-743, 726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Activity of various thiocarboxanilide derivatives against wild-type and several mutant human immunodeficiency virus type 1 strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

The M184V mutation in HIV-1 reverse transcriptase (RT) conferring lamivudine resistance does not result in broad cross-resistance to nucleoside analogue RT inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Distribution of K103N and/or Y181C HIV-1 mutations by exposure to zidovudine and non-nucleoside reverse transcriptase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Development of drug resistance in patients receiving combinations of zidovudine, didanosine and nevirapine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Checking your imagination: applications of the free R value

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Protein–nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

Increased yield of homogeneous HIV-1 reverse transcriptase (p66/p51) using a slow purification approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1046/J.1432-1327.2002.02811.X

10.1046/J.1432-1327.2002.02811.X

21 January 2018

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11895437 AND SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017