Structure of a cytochrome P450-redox partner electron-transfer complex (Q27617426)

1

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H Li

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H Zhang

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J A Peterson

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T L Poulos

full work available at URL

5

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language of work or name

English

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publication date

2 March 1999

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC26702

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published in

Proceedings of the National Academy of Sciences of the United States of America

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volume

96

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issue

5

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page(s)

1863-8

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Comparison of the crystal structures of a flavodoxin in its three oxidation states at cryogenic temperatures

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Identification by site-directed mutagenesis of two lysine residues in cholesterol side chain cleavage cytochrome P450 that are essential for adrenodoxin binding

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Coding nucleotide sequence of rat NADPH-cytochrome P-450 oxidoreductase cDNA and identification of flavin-binding domains

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Characterization of a catalytically self-sufficient 119,000-dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium.

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Expression, purification, and properties of the flavoprotein domain of cytochrome P-450BM-3. Evidence for the importance of the amino-terminal region for FMN binding

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Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms

29 September 2017

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The cytochrome P450 2B4-NADPH cytochrome P450 reductase electron transfer complex is not formed by charge-pairing

29 September 2017

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Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase.

29 September 2017

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Redox Control of the Catalytic Cycle of Flavocytochrome P-450 BM3

2 June 2018

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Equilibrium and transient state spectrophotometric studies of the mechanism of reduction of the flavoprotein domain of P450BM-3.

2 June 2018

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Coding nucleotide, 5' regulatory, and deduced amino acid sequences of P-450BM-3, a single peptide cytochrome P-450:NADPH-P-450 reductase from Bacillus megaterium

2 June 2018

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Reconstitution of the fatty acid hydroxylation function of cytochrome P-450BM-3 utilizing its individual recombinant hemo- and flavoprotein domains

2 June 2018

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Regulation of oxidation-reduction potentials through redox-linked ionization in the Y98H mutant of the Desulfovibrio vulgaris [Hildenborough] flavodoxin: direct proton nuclear magnetic resonance spectroscopic evidence for the redox-dependent shift i

2 June 2018

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The flavoprotein domain of P450BM-3: expression, purification, and properties of the flavin adenine dinucleotide- and flavin mononucleotide-binding subdomains

2 June 2018

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The domain architecture of cytochrome P450BM-3.

21 January 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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Modeling protein-substrate interactions in the heme domain of cytochrome P450(BM-3).

21 January 2018

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Structure and function of cytochromes P450: a comparative analysis of three crystal structures

21 January 2018

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Negatively Charged Anabaena Flavodoxin Residues (Asp144 and Glu145) Are Important for Reconstitution of Cytochrome P450 17α-Hydroxylase Activity

21 January 2018

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Critical residues involved in FMN binding and catalytic activity in cytochrome P450BM-3.

21 January 2018

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Determination of cytochrome b5 association reactions. Characterization of metmyoglobin and cytochrome P-450cam binding to genetically engineered cytochromeb5

27 November 2018

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Electrostatic interactions during electron transfer reactions between c-type cytochromes and flavodoxin

27 November 2018

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Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

27 November 2018

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12 December 2020

Characterization of recombinant Bacillus megaterium cytochrome P-450 BM-3 and its two functional domains

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12 December 2020

The cytochrome P-450cam binding surface as defined by site-directed mutagenesis and electrostatic modeling

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12 December 2020

Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex

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12 December 2020

Role of electrostatic interactions in the reaction of NADPH-cytochrome P-450 reductase with cytochromes P-450

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12 December 2020

The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450

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12 December 2020

Electrostatic orientation during electron transfer between flavodoxin and cytochrome c

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12 December 2020

Selective chemical modification of a functionally linked lysine in cytochrome P-450 LM2

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12 December 2020

Separate roles for FMN and FAD in catalysis by liver microsomal NADPH-cytochrome P-450 reductase

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12 December 2020

The kinetics of reduction of cytochrome P-450cam by reduced putidaredoxin

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12 December 2020

Site-directed mutagenesis of tyrosine-98 in the flavodoxin from Desulfovibrio vulgaris (Hildenborough): regulation of oxidation-reduction properties of the bound FMN cofactor by aromatic, solvent, and electrostatic interactions

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12 December 2020

Role of lysine and arginine residues of cytochrome P450 in the interaction between cytochrome P4502B1 and NADPH-cytochrome P450 reductase

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12 December 2020

The cumulative electrostatic effect of aromatic stacking interactions and the negative electrostatic environment of the flavin mononucleotide binding site is a major determinant of the reduction potential for the flavodoxin from Desulfovibrio vulgar

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12 December 2020

Domain-domain interaction in cytochrome P450BM-3

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12 December 2020

Reconstitution of the fatty acid hydroxylase activity of cytochrome P450BM-3 utilizing its functional domains

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12 December 2020

Evaluation of the Role of Specific Acidic Amino Acid Residues in Electron Transfer between the Flavodoxin and Cytochrome c3 from Desulfovibrio vulgaris [Hildenborough]

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12 December 2020