Oxysterol-binding protein KES1 YPL145C (Q27550815)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35844

Oxysterol-binding protein superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35844

Oxysterol-binding protein, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

sterol transporter activity

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

16 July 2018

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

16 July 2018

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

phosphatidic acid binding

1 reference

14 February 2019

Lipid Binding Requirements for Oxysterol-binding Protein Kes1 Inhibition of Autophagy and Endosome-trans-Golgi Trafficking Pathways*

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

phosphatidylinositol-4-phosphate binding

phosphatidylinositol-4,5-bisphosphate binding

IPI

2 references

lipid binding

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

16 July 2018

16 July 2018

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

oxysterol binding

Overlapping functions of the yeast oxysterol-binding protein homologues.

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

ISS

5 June 2018

Structural mechanism for sterol sensing and transport by OSBP-related proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

IPI

5 June 2018

Structural mechanism for sterol sensing and transport by OSBP-related proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

phosphatidylinositol-4,5-bisphosphate binding

1 reference

14 February 2019

Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

oxysterol binding

ISS

oxysterol binding

Overlapping functions of the yeast oxysterol-binding protein homologues.

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

ISS

14 February 2019

Structural mechanism for sterol sensing and transport by OSBP-related proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

lipid binding

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

14 February 2019

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

sterol transporter activity

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

sterol binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

extrinsic component of membrane

cell component

1 reference

14 February 2019

Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

cytoplasm

1 reference

10 September 2018

Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

1 reference

16 July 2018

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

1 reference

14 February 2019

cytosol

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

intracellular membrane-bounded organelle

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

cytoplasm

HDA

cytosol

HDA

steroid biosynthetic process

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

1 reference

14 February 2019

sphingolipid metabolic process

1 reference

14 February 2019

The yeast oxysterol binding protein Kes1 maintains sphingolipid levels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

endocytosis

1 reference

16 July 2018

A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

steroid metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

1 reference

14 February 2019

positive regulation of phosphatase activity

1 reference

14 February 2019

Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

post-Golgi vesicle-mediated transport

2 references

14 February 2019

Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

lipid transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

1 reference

14 February 2019

piecemeal microautophagy of the nucleus

1 reference

16 July 2018

Nvj1p is the outer-nuclear-membrane receptor for oxysterol-binding protein homolog Osh1p in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

lipid metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

1 reference

14 February 2019

ER to Golgi ceramide transport

1 reference

14 February 2019

Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

sterol biosynthetic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

1 reference

14 February 2019

maintenance of cell polarity

1 reference

16 July 2018

Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

sterol transport

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

14 February 2019

Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35844

exocytosis

1 reference

16 July 2018

Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35844&geneProductId=UniProtKB:P35844

exocytosis

endocytosis

maintenance of cell polarity

piecemeal microautophagy of the nucleus

Oxysterol-binding protein, conserved site

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35844

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference