Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase YJL130C (Q27548512)

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fungal protein found in Saccharomyces cerevisiae S288c

URA2
bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase
YJL130C

Language	Label	Description	Also known as
English	Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase YJL130C	fungal protein found in Saccharomyces cerevisiae S288c	URA2 bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase YJL130C

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Carbamoyl-phosphate synthase, large subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

ATP-grasp fold, subdomain 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Metal-dependent hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Class I glutamine amidotransferase-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Methylglyoxal synthase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Pre-ATP-grasp domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Aspartate/ornithine carbamoyltransferase superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Aspartate carbamoyltransferase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Carbamoyl-phosphate synthase, small subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Methylglyoxal synthase-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

ATP-grasp fold, protein family

1 reference

based on heuristic

inferred from protein domain or family

Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Carbamoyl-phosphate synthase small subunit, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glutamine amidotransferase-like

1 reference

based on heuristic

inferred from protein domain or family

Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Carbamoyl-phosphate synthase small subunit, GATase1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Carbamoyl-phosphate synthase large subunit, CPSase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Carbamoyl-phosphate synthetase, large subunit oligomerisation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

catalytic activity

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

metal ion binding

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

amino acid binding

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

transferase activity

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

carboxyl- or carbamoyltransferase activity

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

determination method or standard

3 references

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

The aspartate transcarbamylase and carbamoyl phosphate synthetase of yeast: A multi-functional enzyme complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

ligase activity

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

aspartate carbamoyltransferase activity

determination method or standard

4 references

5 June 2018

Regulation of Orotidylic Acid Pyrophosphorylase in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

Half of Saccharomyces cerevisiae carbamoyl phosphate synthetase produces and channels carbamoyl phosphate to the fused aspartate transcarbamoylase domain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

nucleotide binding

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

carbamoyl-phosphate synthase (ammonia) activity

determination method or standard

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

dihydroorotase activity

determination method or standard

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

protein binding

determination method or standard

5 references

5 June 2018

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

Proteome survey reveals modularity of the yeast cell machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

An atlas of chaperone-protein interactions in Saccharomyces cerevisiae: implications to protein folding pathways in the cell

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

aspartate carbamoyltransferase activity

determination method or standard

5 references

9 May 2019

Regulation of Orotidylic Acid Pyrophosphorylase in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

Half of Saccharomyces cerevisiae carbamoyl phosphate synthetase produces and channels carbamoyl phosphate to the fused aspartate transcarbamoylase domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

determination method or standard

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

The aspartate transcarbamylase and carbamoyl phosphate synthetase of yeast: A multi-functional enzyme complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

dihydroorotase activity

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

integral component of membrane

determination method or standard

1 reference

9 May 2019

Enzymatic activities of Ura2 and Ura1 proteins (aspartate carbamoyltransferase and dihydro-orotate dehydrogenase) are present in both isolated membranes and cytoplasm of Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

determination method or standard

determination method or standard

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

The yeast Ura2 protein that catalyses the first two steps of pyrimidines biosynthesis accumulates not in the nucleus but in the cytoplasm, as shown by immunocytochemistry and Ura2-green fluorescent protein mapping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

biological process

nitrogen compound metabolic process

determination method or standard

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

pyrimidine nucleotide biosynthetic process

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

negative regulation of pyrimidine nucleobase metabolic process

determination method or standard

1 reference

9 May 2019

Regulation of Pyrimidine Biosynthesis in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

'de novo' UMP biosynthetic process

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

'de novo' pyrimidine nucleobase biosynthetic process

determination method or standard

3 references

5 June 2018

Regulation of Orotidylic Acid Pyrophosphorylase in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

5 June 2018

Fine structure of the URA2 locus in Saccharomyces cerevisiae. II. Meiotic and mitotic mapping studies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

cellular amino acid metabolic process

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

determination method or standard

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

arginine biosynthetic process

determination method or standard

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

'de novo' pyrimidine nucleobase biosynthetic process

determination method or standard

4 references

9 May 2019

Regulation of Orotidylic Acid Pyrophosphorylase in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

Fine structure of the URA2 locus in Saccharomyces cerevisiae. II. Meiotic and mitotic mapping studies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

UTP biosynthetic process

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

glutamine metabolic process

determination method or standard

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

Regulation of Pyrimidine Biosynthesis in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

citrulline biosynthetic process

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07259

determination method or standard

negative regulation of pyrimidine nucleobase metabolic process

determination method or standard

carbamoyl phosphate biosynthetic process

determination method or standard

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P07259&geneProductId=UniProtKB:P07259

determination method or standard

Carbamoyl-phosphate synthase small subunit, N-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Methylglyoxal synthase-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Carbamoyl-phosphate synthetase, large subunit oligomerisation domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Glutamine amidotransferase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Carbamoyl-phosphate synthase large subunit, CPSase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Carbamoyl-phosphate synthase small subunit, GATase1 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07259

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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