Phosphatidylinositol 3-kinase VPS34 YLR240W (Q27547497)

Protein kinase-like domain superfamily

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily

1 reference

Phosphatidylinositol kinase family

1 reference

Armadillo-type fold

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family

1 reference

Phosphatidylinositol 3-kinase, C2 domain, protein family

1 reference

Phosphoinositide 3-kinase, accessory (PIK) domain, protein family

1 reference

Phosphatidylinositol 3/4-kinase, conserved site, protein family

1 reference

Saccharomyces cerevisiae S288c

found in taxon

1 reference

25 May 2022

1 reference

25 May 2022

protein kinase activity

1 reference

14 February 2019

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

ATP binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1 reference

14 February 2019

1-phosphatidylinositol-3-kinase activity

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

21 June 2018

21 June 2018

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

21 June 2018

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1 reference

14 February 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1 reference

14 February 2019

protein binding

3 references

14 February 2019

A global protein kinase and phosphatase interaction network in yeast.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1-phosphatidylinositol-3-kinase activity

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

14 February 2019

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

cell component

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1 reference

14 February 2019

fungal-type vacuole membrane

1 reference

10 September 2018

Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

peroxisome

1 reference

21 June 2018

The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

phosphatidylinositol 3-kinase complex, class III, type II

1 reference

21 June 2018

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

membrane

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

1 reference

21 June 2018

phagophore assembly site

1 reference

21 June 2018

Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

phosphatidylinositol 3-kinase complex, class III, type I

1 reference

21 June 2018

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

endosome membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1 reference

14 February 2019

nucleus-vacuole junction

1 reference

14 February 2019

Vps factors are required for efficient transcription elongation in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

nuclear pore

1 reference

10 September 2018

Vps factors are required for efficient transcription elongation in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

phagophore assembly site

cytoplasm

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

3 references

14 February 2019

14 February 2019

Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

peroxisome

phosphatidylinositol 3-kinase complex, class III, type I

phosphatidylinositol 3-kinase complex, class III, type II

fungal-type vacuole membrane

HDA

cytosol

HDA

1 reference

14 February 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

HDA

biological process

protein phosphorylation

1 reference

21 June 2018

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

phosphatidylinositol phosphate biosynthetic process

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

21 June 2018

21 June 2018

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

21 June 2018

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1 reference

14 February 2019

autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1 reference

14 February 2019

protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

1 reference

14 February 2019

autophagy of peroxisome

1 reference

21 June 2018

The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

positive regulation of transcription elongation from RNA polymerase II promoter

1 reference

14 February 2019

Vps factors are required for efficient transcription elongation in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

phosphatidylinositol-3-phosphate biosynthetic process

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

autophagosome assembly

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

endosomal transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P22543&geneProductId=UniProtKB:P22543

1 reference

21 June 2018

positive regulation of macroautophagy

1 reference

14 February 2019

The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

regulation of protein localization by the Cvt pathway

1 reference

14 February 2019

The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

endocytosis

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

protein phosphorylation

autophagy of peroxisome

phosphatidylinositol-3-phosphate biosynthetic process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

phosphatidylinositol phosphate biosynthetic process

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

14 February 2019

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22543

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference