Hepatitis C Virus Inhibits Cell Surface Expression of HLA-DR, Prevents Dendritic Cell Maturation, and Induces Interleukin-10 Production (Q27485530)

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Malika Ait-Goughoulte

2

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Steven M Truscott

3

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Keith Meyer

4

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Azra Blazevic

5

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Getahun Abate

6

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Daniel F Hoft

8

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Ranjit Ray

Dendritic Cell Function during Chronic Hepatitis C Virus and Human Immunodeficiency Virus Type 1 Infection

9

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publication date

April 2008

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published in

Journal of Virology

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volume

82

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issue

7

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page(s)

3320-8

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cites work

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Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA.

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High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

29 September 2017

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Specific detection of hepatitis C virus minus strand RNA in hematopoietic cells

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Association between MHC class II alleles and clearance of circulating hepatitis C virus. Members of the Trent Hepatitis C Virus Study Group

2 June 2018

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Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene

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Transcriptional regulation of cellular and viral promoters by the hepatitis C virus core protein

2 June 2018

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Class II transactivator regulates the expression of multiple genes involved in antigen presentation

2 June 2018

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Decrease and dysfunction of dendritic cells correlate with impaired hepatitis C virus-specific CD4 T-cell proliferation in patients with hepatitis C virus infection.

2 June 2018

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Microarray analyses and molecular profiling of Stat3 signaling pathway induced by hepatitis C virus core protein in human hepatocytes

27 November 2018

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Constitutive expression of CIITA directs CD4 T cells to produce Th2 cytokines in the thymus.

27 November 2018

1 reference

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Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes.

27 November 2018

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Presence of functional dendritic cells in patients chronically infected with hepatitis C virus

27 November 2018

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Chronic hepatitis C virus infection established and maintained in chimpanzees independent of dendritic cell impairment

27 November 2018

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Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection

27 November 2018

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Immune responses in hepatitis C virus infection: the role of dendritic cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268470

Hepatitis C virus core protein modulates the interferon-induced transacting factors of Jak/Stat signaling pathway but does not affect the activation of downstream IRF-1 or 561 gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268470

Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268470

Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268470

Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268470

Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268470

The MHC is a major determinant of viral status, but not fibrotic stage, in individuals infected with hepatitis C

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18216090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Dendritic cells and hepatitis C virus]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18216090