Phenotypic Characterization of Resistant Val36 Variants of Hepatitis C Virus NS3-4A Serine Protease (Q27485288)

2

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Brian L Hanzelka

3

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Ute Müh

4

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Yunyi Wei

5

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Hui-May Chu

6

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Ann M Tigges

7

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Debra L Brennan

8

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B Govinda Rao

9

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Lora Swenson

10

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Ann D Kwong

11

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Chao Lin

Antimicrobial Agents and Chemotherapy

12

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language of work or name

English

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publication date

January 2008

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published in

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volume

52

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issue

1

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page(s)

110-20

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cites work

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Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus

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Discovery and development of VX-950, a novel, covalent, and reversible inhibitor of hepatitis C virus NS3.4A serine protease

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In vitro selected Con1 subgenomic replicons resistant to 2'-C-methyl-cytidine or to R1479 show lack of cross resistance

29 September 2017

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Identification and analysis of fitness of resistance mutations against the HCV protease inhibitor SCH 503034.

29 September 2017

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Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations

29 September 2017

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Binding site characterization and resistance to a class of non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase

29 September 2017

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Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients.

29 September 2017

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Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro

29 September 2017

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29 September 2017

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29 September 2017

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Mechanism of action and antiviral activity of benzimidazole-based allosteric inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.

29 September 2017

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Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro

29 September 2017

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Treatment of chronic hepatitis C: a systematic review

29 September 2017

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29 September 2017

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The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay

29 September 2017

1 reference

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Mechanistic Role of an NS4A Peptide Cofactor with the Truncated NS3 Protease of Hepatitis C Virus: Elucidation of the NS4A Stimulatory Effect via Kinetic Analysis and Inhibitor Mapping

29 September 2017

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Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir

2 June 2018

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SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonresponders

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223918

Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223918

In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223918

In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223918

A continuous assay of hepatitis C virus protease based on resonance energy transfer depsipeptide substrates

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223918

The natural history of hepatitis C virus infection

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17938182

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.00863-07

1 reference

release_kxbxozmak5hexhv5a6mock4jbu

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

17938182

1 reference