Broad Specificity of Virus-Specific CD4 T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection (Q27472915)

7

object named as

Raymond T Chung

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Georg M Lauer

object named as

Georg M Lauer

2

1 reference

ORCID Public Data File 2021

author name string

Cheryl L Day

1

0 references

Gregory K Robbins

3

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Barbara McGovern

4

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Alysse G Wurcel

5

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Rajesh T Gandhi

Detection of Diverse Hepatitis C Virus (HCV)-Specific Cytotoxic T Lymphocytes in Peripheral Blood of Infected Persons by Screening for Responses to All Translated Proteins of HCV

6

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language of work or name

1 reference

December 2002

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published in

Journal of Virology

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volume

76

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issue

24

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page(s)

12584-95

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Viral immune evasion due to persistence of activated T cells without effector function

21 March 2017

1 reference

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Hepatitis C virus infection

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Analysis of successful immune responses in persons infected with hepatitis C virus

21 March 2017

1 reference

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Determinants of viral clearance and persistence during acute hepatitis C virus infection

21 March 2017

1 reference

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Vigorous HIV-1-Specific CD4 T Cell Responses Associated with Control of Viremia

21 March 2017

1 reference

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Recurrence of hepatitis C virus after loss of virus-specific CD4( ) T-cell response in acute hepatitis C

21 March 2017

1 reference

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The prevalence of hepatitis C virus infection in the United States, 1988 through 1994

7 April 2017

1 reference

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Analysis of a successful immune response against hepatitis C virus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response

7 April 2017

1 reference

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Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

7 April 2017

1 reference

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Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins

7 April 2017

1 reference

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The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes

7 April 2017

1 reference

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Impairment of CD4( ) T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants

9 May 2017

1 reference

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Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by elispot and intracellular cytokine staining assays

29 September 2017

1 reference

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Differential CD4( ) and CD8( ) T-cell responsiveness in hepatitis C virus infection

29 September 2017

1 reference

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Diminished primary and secondary influenza virus-specific CD8( ) T-cell responses in CD4-depleted Ig(-/-) mice.

29 September 2017

1 reference

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HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles

29 September 2017

1 reference

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Immunobiology of hepatitis C virus (HCV) infection: the role of CD4 T cells in HCV infection

29 September 2017

1 reference

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Cytokine-induced viral purging--role in viral pathogenesis.

29 September 2017

1 reference

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Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte.

29 September 2017

1 reference

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Several common HLA-DR types share largely overlapping peptide binding repertoires

29 September 2017

1 reference

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Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice

29 September 2017

1 reference

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Immunodominant CD4 T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection

29 September 2017

1 reference

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A critical role for neutralizing-antibody-producing B cells, CD4( ) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Progressive loss of CD8 T cell-mediated control of a gamma-herpesvirus in the absence of CD4 T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

CD4 T cells are required to sustain CD8 cytotoxic T-cell responses during chronic viral infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Enhanced establishment of a virus carrier state in adult CD4 T-cell-deficient mice.

29 September 2017

1 reference

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The scientific challenge of hepatitis C.

29 September 2017

1 reference

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Mutations in immunodominant T cell epitopes derived from the nonstructural 3 protein of hepatitis C virus have the potential for generating escape variants that may have important consequences for T cell recognition.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Dose-dependent acute clearance of hepatitis C genotype 1 virus with interferon alfa

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Liver-infiltrating and circulating CD4 T cells in chronic hepatitis C: immunodominant epitopes, HLA-restriction and functional significance.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Comprehensive, serologically equivalent DNA typing for HLA-B by PCR using sequence-specific primers (PCR-SSP).

2 June 2018

1 reference

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On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Intrahepatic and circulating HLA class II-restricted, hepatitis C virus-specific T cells: functional characterization in patients with chronic hepatitis C.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Frequencies of HCV-specific effector CD4 T cells by flow cytometry: correlation with clinical disease stages

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Characterization of novel HLA-DR11-restricted HCV epitopes reveals both qualitative and quantitative differences in HCV-specific CD4 T cell responses in chronically infected and non-viremic patients

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

CD4 T-cell-epitope escape mutant virus selected in vivo

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Association of multispecific CD4( ) response to hepatitis C and severity of recurrence after liver transplantation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Conserved hepatitis C virus sequences are highly immunogenic for CD4( ) T cells: implications for vaccine development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

HIV-1-specific CD4 T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Immunological control of a murine gammaherpesvirus independent of CD8 T cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Absence of recoverable infectious virus and unique immune responses in an asymptomatic HIV long-term survivor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Mapping of immunodominant CD4 T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Interferon gamma production by peripheral blood lymphocytes to hepatitis C virus core protein in chronic hepatitis C infection

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

A helper T-cell antigen enhances generation of hepatitis C virus-specific cytotoxic T lymphocytes in vitro

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136690

Phototyping: comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP)

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12438584

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Natural analogue peptides of an HIV-1 GP120 T-helper epitope antagonize response of GP120-specific human CD4 T-cell clones

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12438584

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.76.24.12584-12595.2002

1 reference

1 reference

1 reference

PubMed publication ID

12438584

1 reference