Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome (Q27471683)

4 July 2017

title

Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome (English)

1 reference

4 July 2017

1 reference

1 reference

3

Harvey J Alter

1 reference

4 July 2017

13

Robert H Purcell

1 reference

4 July 2017

Patrizia Farci

1

1 reference

4 July 2017

Rita Strazzera

2

1 reference

4 July 2017

Stefania Farci

4

1 reference

4 July 2017

Daniela Degioannis

5

1 reference

4 July 2017

Alessandra Coiana

6

1 reference

4 July 2017

Giovanna Peddis

7

1 reference

4 July 2017

Francesco Usai

8

1 reference

4 July 2017

Giancarlo Serra

9

1 reference

4 July 2017

Luchino Chessa

10

1 reference

4 July 2017

Giacomo Diaz

11

1 reference

4 July 2017

Angelo Balestrieri

12

1 reference

4 July 2017

language of work or name

English

0 references

publication date

1 March 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 July 2017

published in

1 reference

4 July 2017

volume

99

1 reference

4 July 2017

issue

5

1 reference

4 July 2017

page(s)

3081-3086

1 reference

Prospective characterization of full-length hepatitis C virus NS5A quasispecies during induction and combination antiviral therapy

4 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Genetic heterogeneity of hypervariable region 1 of the hepatitis C virus (HCV) genome and sensitivity of HCV to alpha interferon therapy

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Evolution of the hepatitis C virus second envelope protein hypervariable region in chronically infected patients receiving alpha interferon therapy

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Recovery, persistence, and sequelae in hepatitis C virus infection: a perspective on long-term outcome

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Avoiding false positives with PCR

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Lack of Protective Immunity Against Reinfection with Hepatitis C Virus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Hepatitis C virus resistance to antiviral therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Interaction between the hepatitis C virus and the immune system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Clinical significance of hepatitis C virus genotypes and quasispecies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Strategies and prospects for vaccination against the hepatitis C viruses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Factors predictive of a beneficial response to therapy of hepatitis C

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Human immunodeficiency virus type 1 genetic evolution in children with different rates of development of disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Maintaining the integrity of human immunodeficiency virus sequence databases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Therapy of acute and chronic viral hepatitis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Mutations of hepatitis C virus 1b NS5A 2209–2248 amino acid sequence do not predict the response to recombinant interferon-alfa therapy in French patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Mutations in the nonstructural 5A region of hepatitis C virus and response of chronic hepatitis C to interferon alfa.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Quasispecies nature of hepatitis C virus and response to alpha interferon: significance as a predictor of direct response to interferon

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Hepatitis C virus genome complexity correlates with response to interferon therapy: a study in French patients with chronic hepatitis C.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Mutations in the nonstructural 5A gene of European hepatitis C virus isolates and response to interferon alfa

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Hepatitis C viral complexity detected by single-strand conformation polymorphism and response to interferon therapy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Influence of viral quasispecies on effectiveness of interferon therapy in chronic hepatitis C patients

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

A long-term study of hepatitis C virus replication in non-A, non-B hepatitis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Randomised trial of interferon alpha2b plus ribavirin for 48 weeks or for 24 weeks versus interferon alpha2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (I

2 June 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Hepatitis C virus and interferon resistance: it's more than just PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Mutations in the NS5A gene of hepatitis C virus in North American patients infected with HCV genotype 1a or 1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Hepatitis C virus, the E2 envelope protein, and alpha-interferon resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Association of amino acid sequence in the PKR-eIF2 phosphorylation homology domain and response to interferon therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Mutations within the E2 and NS5A protein in patients infected with hepatitis C virus type 3a and correlation with treatment response

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Mutations in the E2-PePHD and NS5A region of hepatitis C virus type 1 and the dynamics of hepatitis C viremia decline during interferon alfa treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Clinical implications of viral quasispecies heterogeneity in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Viral escape and the failure of cellular immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.052712599

Mutations in the NS5A region do not predict interferon-responsiveness in american patients infected with genotype 1b hepatitis C virus

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

Diversity of quasispecies in various disease stages of chronic hepatitis C virus infection and its significance in interferon treatment

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122476

27 November 2018

Identifiers

DOI

10.1073/PNAS.052712599

1 reference

release_opc3hmsf3vfxpfnkg664j7ykq4

4 July 2017

0 references

0 references

PMC publication ID

122476

1 reference

4 July 2017

1 reference