A loss of FUS/TLS function leads to impaired cellular proliferation (Q27331026)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25501833 AND SRC:MED&resulttype=core&format=json

24 February 2020

title

A loss of FUS/TLS function leads to impaired cellular proliferation (English)

1 reference

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24 February 2020

9

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24 February 2020

7

J E Landers

1 reference

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24 February 2020

author name string

C L Ward

1

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24 February 2020

K J Boggio

2

1 reference

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24 February 2020

B N Johnson

3

1 reference

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24 February 2020

J B Boyd

4

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24 February 2020

S Douthwright

5

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24 February 2020

S A Shaffer

6

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24 February 2020

M A Glicksman

8

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24 February 2020

language of work or name

English

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publication date

11 December 2014

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24 February 2020

published in

Cell Death and Disease

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24 February 2020

volume

5

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24 February 2020

issue

12

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page(s)

e1572

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Creative Commons Attribution 4.0 International

24 February 2020

copyright license

start time

1 December 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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19 March 2017

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19 March 2017

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Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

19 March 2017

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Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

19 March 2017

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The antidepressant and antiinflammatory effects of rolipram in the central nervous system

19 March 2017

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Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

19 March 2017

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FUS pathology in basophilic inclusion body disease

19 March 2017

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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

19 March 2017

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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

19 March 2017

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An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation

19 March 2017

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Doxycycline alters metabolism and proliferation of human cell lines

19 March 2017

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Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs

19 March 2017

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Functions of FUS/TLS from DNA repair to stress response: implications for ALS.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Identification of FUS p.R377W in essential tremor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress

28 September 2017

1 reference

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Fused in sarcoma (FUS): an oncogene goes awry in neurodegeneration

28 September 2017

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Microglia: scapegoat, saboteur, or something else?

28 September 2017

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Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Exome sequencing identifies FUS mutations as a cause of essential tremor

28 September 2017

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Advances in understanding the molecular basis of frontotemporal dementia

28 September 2017

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Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches.

28 September 2017

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Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies.

28 September 2017

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Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS

28 September 2017

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TDP-43 and FUS RNA-binding proteins bind distinct sets of cytoplasmic messenger RNAs and differently regulate their post-transcriptional fate in motoneuron-like cells.

28 September 2017

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RNA targets of wild-type and mutant FET family proteins

28 September 2017

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The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.

28 September 2017

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Chemistry and biology of mammalian metallothioneins.

28 September 2017

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Pathological heterogeneity in amyotrophic lateral sclerosis with FUS mutations: two distinct patterns correlating with disease severity and mutation

28 September 2017

1 reference

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PGC-1α regulates translocated in liposarcoma activity: role in oxidative stress gene expression

28 September 2017

1 reference

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Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

28 September 2017

1 reference

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Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Advances in thymosin beta10 research: differential expression, molecular mechanisms, and clinical implications in cancer and other conditions

28 September 2017

1 reference

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S100A6 - new facts and features

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

The TET family of proteins: functions and roles in disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Attenuation of MPTP neurotoxicity by rolipram, a specific inhibitor of phosphodiesterase IV.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Relative quantification of proteins in human cerebrospinal fluids by MS/MS using 6-plex isobaric tags

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Ageing and neuronal vulnerability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

The role of S100A6 in pancreatic cancer development and its clinical implication as a diagnostic marker and therapeutic target.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

The phosphodiesterase inhibitor rolipram delivered after a spinal cord lesion promotes axonal regeneration and functional recovery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Specificity of TLS-CHOP rearrangement for classic myxoid/round cell liposarcoma: absence in predominantly myxoid well-differentiated liposarcomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

The phosphodiesterase inhibitors pentoxifylline and rolipram suppress macrophage activation and nitric oxide production in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Male sterility and enhanced radiation sensitivity in TLS(-/-) mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Regulation of telomere length by G-quadruplex telomere DNA- and TERRA-binding protein TLS/FUS.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Ewing sarcoma with novel translocation t(2;16) producing an in-frame fusion of FUS and FEV.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

FUS-immunoreactive intranuclear inclusions in neurodegenerative disease.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038/CDDIS.2014.508

Identification of a novel risk variant in the FUS gene in essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CDDIS.2014.508

Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CDDIS.2014.508

Preventive effect of rolipram, a phosphodiesterase 4 enzyme inhibitor, on oxidative renal injury in acute ascending pyelonephritis model in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CDDIS.2014.508

FUS/TLS-immunoreactive neuronal and glial cell inclusions increase with disease duration in familial amyotrophic lateral sclerosis with an R521C FUS/TLS mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CDDIS.2014.508

Optimized fast and sensitive acquisition methods for shotgun proteomics on a quadrupole orbitrap mass spectrometer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CDDIS.2014.508

Metallothioneins: mercury species-specific induction and their potential role in attenuating neurotoxicity

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

FUS/ERG gene fusions in Ewing's tumors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4649830

Genetic characterization of angiomatoid fibrous histiocytoma identifies fusion of the FUS and ATF-1 genes induced by a chromosomal translocation involving bands 12q13 and 16p11

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25501833

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fusion of the FUS gene with ERG in acute myeloid leukemia with t(16;21)(p11;q22)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25501833

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25501833

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2014.508

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25501833 AND SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25501833 AND SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

25501833

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25501833 AND SRC:MED&resulttype=core&format=json