Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models (Q27301158)

3

object named as

Laurent Mouchiroud

0 references

Vincenzo Sorrentino

object named as

Vincenzo Sorrentino

4

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author name string

Matteo Cornaglia

1

0 references

Gopalan Krishnamani

2

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Thomas Lehnert

5

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Martin A M Gijs

Molecular Neurodegeneration

7

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language of work or name

English

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publication date

2016

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published in

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volume

11

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issue

1

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page(s)

17

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cites work

Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Hydrogel-droplet microfluidic platform for high-resolution imaging and sorting of early larval Caenorhabditis elegans

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

State of play in amyotrophic lateral sclerosis genetics

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Laterally orienting C. elegans using geometry at microscale for high-throughput visual screens in neurodegeneration and neuronal development studies

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

On-demand optical immobilization of Caenorhabditis elegans for high-resolution imaging and microinjection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

ALS and neuromuscular disease: in search of the Holy Grail

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Modeling neurodegenerative diseases in Caenorhabditis elegans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

The NAD( )/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Mitonuclear protein imbalance as a conserved longevity mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Pharmacological approaches to restore mitochondrial function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Exploring living multicellular organisms, organs, and tissues using microfluidic systems

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

A microfluidic device for whole-animal drug screening using electrophysiological measures in the nematode C. elegans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Microfluidic chamber arrays for whole-organism behavior-based chemical screening

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

ALS genetic modifiers that increase survival of SOD1 mice and are suitable for therapeutic development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Subcellular in vivo time-lapse imaging and optical manipulation of Caenorhabditis elegans in standard multiwell plates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

A programmable microvalve-based microfluidic array for characterization of neurotoxin-induced responses of individual C. elegans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Worm chips: microtools for C. elegans biology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Femtosecond laser nanoaxotomy lab-on-a-chip for in vivo nerve regeneration studies.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Amyotrophic lateral sclerosis: from current developments in the laboratory to clinical implications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

A three-dimensional human neural cell culture model of Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Astrocyte-neuron co-culture on microchips based on the model of SOD mutation to mimic ALS.

31 May 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Maze exploration and learning in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Long-term high-resolution imaging and culture of C. elegans in chip-gel hybrid microfluidic device for developmental studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

C.L.I.P.--continuous live imaging platform for direct observation of C. elegans physiological processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Undulatory Swimming in Viscoelastic Fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

Amyloid-beta (Aβ1-42)-induced paralysis in Caenorhabditis elegans is reduced by restricted cholesterol supply.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13024-016-0083-6

A Systematic RNAi Screen of Neuroprotective Genes Identifies Novel Modulators of Alpha-Synuclein-Associated Effects in Transgenic Caenorhabditis elegans.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746889

Polyglutamine proteins at the pathogenic threshold display neuron-specific aggregation in a pan-neuronal Caenorhabditis elegans model

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26858201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Massive Mitochondrial Degeneration in Motor Neurons Triggers the Onset of Amyotrophic Lateral Sclerosis in Mice Expressing a Mutant SOD1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26858201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S13024-016-0083-6

1 reference

Dimensions Publication ID

1024452793

0 references

1 reference

1 reference

PubMed publication ID

26858201

1 reference