Spinal cord injury: a review of current therapy, future treatments, and basic science frontiers (Q27025166)

1

1 reference

Arabinda Das

2

1 reference

Gerald Wallace

3

1 reference

John Barry

4

1 reference

Alexey A. Vertegel

5

1 reference

Swapan K. Ray

6

1 reference

Naren L. Banik

7

1 reference

language of work or name

1 reference

May 2013

1 reference

published in

Neurochemical Research

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volume

38

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issue

5

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page(s)

895-905

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Steroids for acute spinal cord injury

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2-Methoxyestradiol inhibits the up-regulation of AQP4 and AQP1 expression after spinal cord injury

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Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm

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Mesenchymal stem cell graft improves recovery after spinal cord injury in adult rats through neurotrophic and pro-angiogenic actions

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Antioxidant therapies in traumatic brain and spinal cord injury

28 September 2017

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The efficacy of antioxidants in functional recovery of spinal cord injured rats: an experimental study

28 September 2017

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Effect of spinal cord injury and of intrathecal baclofen on brainstem reflexes.

28 September 2017

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Low dose Estrogen Prevents Neuronal Degeneration and Microglial Reactivity in an Acute Model of Spinal Cord Injury: Effect of Dosing, Route of Administration, and Therapy Delay

28 September 2017

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Inhibition of cysteine proteases in acute and chronic spinal cord injury

28 September 2017

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Estrogen receptor agonists and estrogen attenuate TNF- -induced apoptosis in VSC4.1 motoneurons

28 September 2017

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Enzyme-nanoparticle conjugates for biomedical applications.

28 September 2017

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Neuroprotective efficacy of estrogen in experimental spinal cord injury in rats

28 September 2017

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Physiological low dose of estrogen-protected neurons in experimental spinal cord injury

28 September 2017

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Anti-Nogo on the go: from animal models to a clinical trial

28 September 2017

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Autologous bone marrow derived mononuclear cell therapy for spinal cord injury: A phase I/II clinical safety and primary efficacy data

28 September 2017

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The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors

28 September 2017

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Nano-drug delivery and neuroprotection in spinal cord injury.

28 September 2017

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Olfactory mucosal autografts and rehabilitation for chronic traumatic spinal cord injury

28 September 2017

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Chemistry and biology of thyrotropin-releasing hormone (TRH) and its analogs

28 September 2017

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Superoxide dismutase-loaded PLGA nanoparticles protect cultured human neurons under oxidative stress

28 September 2017

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Spatial distribution and acute anti-inflammatory effects of Methylprednisolone after sustained local delivery to the contused spinal cord

28 September 2017

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Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats

28 September 2017

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Disinhibition of neurite growth to repair the injured adult CNS: focusing on Nogo

28 September 2017

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Adult mesenchymal stem cells for tissue engineering versus regenerative medicine.

28 September 2017

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Review of treatment trials in human spinal cord injury: issues, difficulties, and recommendations

28 September 2017

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Extracellular regulators of axonal growth in the adult central nervous system

28 September 2017

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Current status of clinical trials for acute spinal cord injury

28 September 2017

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Macrophages and dendritic cells treatment of spinal cord injury: from the bench to the clinic

28 September 2017

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Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

28 September 2017

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Nogo and axon regeneration

28 September 2017

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Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103794

The role of steroids in acute spinal cord injury: an evidence-based analysis

28 September 2017

1 reference

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Capture of stealth nanoparticles by the body's defences.

28 September 2017

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Acute spinal cord injury, part I: pathophysiologic mechanisms

28 September 2017

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Nanoparticulate systems for brain delivery of drugs

28 September 2017

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28 September 2017

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Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the third National Acute Spinal Cord Injury randomized controlled trial.

28 September 2017

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Adult olfactory epithelium contains multipotent progenitors that give rise to neurons and non-neural cells

28 September 2017

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Cells involved in the capture of nanoparticles in hematopoietic organs

28 September 2017

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Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function

28 September 2017

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Glucocorticoid mechanisms in acute spinal cord injury: a review and therapeutic rationale

28 September 2017

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Gangliosides and their effects on rearranging peripheral and central neural pathways

28 September 2017

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Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. Results of the second National Acute Spinal Cord Injury Study

28 September 2017

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Ganglioside structures and distribution: Are they localized at the nerve ending?

28 September 2017

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Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles

28 September 2017

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Adrenal insufficiency in acute spinal cord injury

31 May 2018

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Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

31 May 2018

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GM1 ganglioside treatment facilitates behavioral recovery from bilateral brain damage

31 May 2018

1 reference

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Endorphins in experimental spinal injury: Therapeutic effect of naloxone

31 May 2018

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Retrograde changes in the nucleus basalis of the rat, caused by cortical damage, are prevented by exogenous ganglioside GM1.

31 May 2018

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Recovery of motor function after spinal-cord injury--a randomized, placebo-controlled trial with GM-1 ganglioside

31 May 2018

1 reference

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Life satisfaction in individuals with a spinal cord injury and pain.

31 May 2018

1 reference

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A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

21 January 2018

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Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats

21 January 2018

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Delayed neuroprotection by riluzole against excitotoxic damage evoked by kainate on rat organotypic spinal cord cultures

21 January 2018

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Combined VEGF and PDGF Treatment Reduces Secondary Degeneration after Spinal Cord Injury

21 January 2018

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Traumatic spinal cord injury alters angiogenic factors and TGF-beta1 that may affect vascular recovery

21 January 2018

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Calpain inhibitor prevented apoptosis and maintained transcription of proteolipid protein and myelin basic protein genes in rat spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

17β-Estradiol inhibits apoptotic cell death of oligodendrocytes by inhibiting RhoA-JNK3 activation after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Suppression of Rho-kinase activity promotes axonal growth on inhibitory CNS substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Local inhibition of Rho signaling by cell-permeable recombinant protein BA-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat.

21 January 2018

1 reference

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Neurotrophin expression in neural stem cells grafted acutely to transected spinal cord of adult rats linked to functional improvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

The retrograde delivery of adenovirus vector carrying the gene for brain-derived neurotrophic factor protects neurons and oligodendrocytes from apoptosis in the chronically compressed spinal cord of twy/twy mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Nanoparticle technology for delivery of drugs across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Delivery of large molecules via poly(butyl cyanoacrylate) nanoparticles into the injured rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Functional silica nanoparticle-mediated neuronal membrane sealing following traumatic spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

High-dose methylprednisolone may cause myopathy in acute spinal cord injury patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Treatment with thyrotropin-releasing hormone (TRH) in patients with traumatic spinal cord injuries

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Measurements and recovery patterns in a multicenter study of acute spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Recruitment and early treatment in a multicenter study of acute spinal cord injury

21 January 2018

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https://api.crossref.org/works/10.1007/S11064-013-0991-6

A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Spinal cord repair with acidic fibroblast growth factor as a treatment for a patient with chronic paraplegia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Acidic fibroblast growth factor for repair of human spinal cord injury: a clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Features of skin-coincubated macrophages that promote recovery from spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Treatment of chronic spinal cord injured patients with autologous bone marrow-derived hematopoietic stem cell transplantation: 1-year follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Case control series of intrathecal autologous bone marrow mesenchymal stem cell therapy for chronic spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Calpain activation in apoptosis of ventral spinal cord 4.1 (VSC4.1) motoneurons exposed to glutamate: calpain inhibition provides functional neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Nitric oxide and superoxide anion differentially activate poly(ADP-ribose) polymerase-1 and Bax to induce nuclear translocation of apoptosis-inducing factor and mitochondrial release of cytochrome c after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

17β-estradiol attenuates neural cell apoptosis through inhibition of JNK phosphorylation in SCI rats and excitotoxicity induced by glutamate in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

The effect of nimodipine and dextran on axonal function and blood flow following experimental spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S11064-013-0991-6

Localized and sustained delivery of fibroblast growth factor-2 from a nanoparticle-hydrogel composite for treatment of spinal cord injury.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103794

Rho signaling pathway targeted to promote spinal cord repair.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103794

Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103794

LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury

28 November 2018

1 reference

12 December 2020

Autologous bone marrow transplantation in patients with subacute and chronic spinal cord injury

1 reference

12 December 2020

Direct evidence for calpain involvement in apoptotic death of neurons in spinal cord injury in rats and neuroprotection with calpain inhibitor

1 reference

12 December 2020

The incidence of neurogenic shock in patients with isolated spinal cord injury in the emergency department

1 reference

12 December 2020

New perspectives for the treatment options in spinal cord injury

1 reference

12 December 2020

Calpeptin and methylprednisolone inhibit apoptosis in rat spinal cord injury

1 reference

12 December 2020

Neuroprotective effects of gacyclidine after experimental photochemical spinal cord lesion in adult rats: dose-window and time-window effects

1 reference

12 December 2020

Pharmacological therapy of spinal cord injury during the acute phase

1 reference

12 December 2020

A critical appraisal of the reporting of the National Acute Spinal Cord Injury Studies (II and III) of methylprednisolone in acute spinal cord injury

1 reference

12 December 2020

Neuroprotective effects of a novel NMDA antagonist, Gacyclidine, after experimental contusive spinal cord injury in adult rats

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12 December 2020

The Sygen multicenter acute spinal cord injury study

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12 December 2020

Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors

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12 December 2020

Early induction of secondary injury factors causing activation of calpain and mitochondria-mediated neuronal apoptosis following spinal cord injury in rats

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12 December 2020

Prevention of damage in acute spinal cord injury by peptides and pharmacologic agents

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12 December 2020

Melatonin inhibits microglial activation, reduces pro-inflammatory cytokine levels, and rescues hippocampal neurons of adult rats with acute Klebsiella pneumoniae meningitis

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12 December 2020

Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro

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12 December 2020

The use of a gold nanoparticle-based adjuvant to improve the therapeutic efficacy of hNgR-Fc protein immunization in spinal cord-injured rats

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12 December 2020

Lactate and pyruvate metabolism in injured cat spinal cord before and after a single large intravenous dose of methylprednisolone

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12 December 2020

Gangliosides enhance neurite outgrowth in PC12 cells

1 reference

12 December 2020

Efficacy of Methylprednisolone in Acute Spinal Cord Injury

1 reference

12 December 2020

Thyrotropin-releasing hormone in experimental spinal injury: dose response and late treatment

1 reference

12 December 2020

Effect of a calcium channel blocker on posttraumatic spinal cord blood flow

1 reference

12 December 2020

Reduction of anterograde degeneration in brain damaged rats by GM1-gangliosides

1 reference

12 December 2020

Effects of treatment with U-74006F on neurological outcome following experimental spinal cord injury

1 reference

12 December 2020

Further Studies of Nimodipine in Experimental Spinal Cord Injury in the Rat

1 reference

12 December 2020

Evaluation of the calcium channel antagonist nimodipine after experimental spinal cord injury

1 reference

12 December 2020

Clinical experience using incubated autologous macrophages as a treatment for complete spinal cord injury: phase I study results

1 reference

12 December 2020

Nogo-A antibody improves regeneration and locomotion of spinal cord-injured rats

1 reference

12 December 2020

Nogo-A–specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates

1 reference

12 December 2020

10.1007/S11064-013-0991-6

Identifiers

DOI

1 reference

Dimensions Publication ID

1016314043

0 references

1 reference

1 reference

PubMed publication ID

23462880

1 reference