The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue (Q27022615)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24506864 AND SRC:MED&resulttype=core&format=json

4 June 2020

Rakesh Srivastava

3

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4 June 2020

author name string

Gwang-Woong Go

1

1 reference

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4 June 2020

Antonio Hernandez-Ono

4

1 reference

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4 June 2020

Gyoungok Gang

5

1 reference

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4 June 2020

Stephen B Smith

6

1 reference

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4 June 2020

Carmen J Booth

7

1 reference

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4 June 2020

Henry N Ginsberg

8

1 reference

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4 June 2020

Arya Mani

9

1 reference

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4 June 2020

language of work or name

1 reference

4 February 2014

1 reference

2 references

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4 June 2020

volume

19

2 references

PubMed

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4 June 2020

issue

2

2 references

PubMed

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4 June 2020

page(s)

209-220

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24506864 AND SRC:MED&resulttype=core&format=json

Identification of cholesterol-regulating genes by targeted RNAi screening

4 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

A simple method for the isolation and purification of total lipides from animal tissues

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Physiological concentrations of insulin promote binding of nuclear proteins to the insulin-like growth factor I gene

21 March 2017

1 reference

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Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

21 March 2017

1 reference

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Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance

21 March 2017

1 reference

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Nonalcoholic fatty liver disease

21 March 2017

1 reference

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Rare nonconservative LRP6 mutations are associated with metabolic syndrome.

7 April 2017

1 reference

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LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Effects of rs7903146 variation in the Tcf7l2 gene in the lipid metabolism of three different populations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

LRP6 Protein Regulates Low Density Lipoprotein (LDL) Receptor-mediated LDL Uptake

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Modulation of canonical Wnt signaling by the extracellular matrix component biglycan

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

An emerging role of mTOR in lipid biosynthesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

A common variant in low-density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-cholesterol

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

LRP6 mutation in a family with early coronary disease and metabolic risk factors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5.

28 September 2017

1 reference

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Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis

28 September 2017

1 reference

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Liver X receptor preferentially activates de novo lipogenesis in human preadipocytes

28 September 2017

1 reference

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Using DNA Microarray to Identify Sp1 as a Transcriptional Regulatory Element of Insulin-Like Growth Factor 1 in Cardiac Muscle Cells

28 September 2017

1 reference

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Premature myocardial infarction is associated with low serum levels of Wnt-1

28 September 2017

1 reference

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Pleiotropic effects of TCF7L2 gene variants and its modulation in the metabolic syndrome: from the LIPGENE study.

28 November 2018

1 reference

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LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins.

28 November 2018

1 reference

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TCF7L2 is associated with high serum triacylglycerol and differentially expressed in adipose tissue in families with familial combined hyperlipidaemia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Development of a novel method to determine very low density lipoprotein kinetics

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Trapping radioactive carbon dioxide during cellular metabolic assays under standard culture conditions: description of a unique gas-capturing device

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Involvement of Sp1 in the transcriptional regulation of the rat insulin-like growth factor-1 gene

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3920193

PREPARATION OF FATTY ACID METHYL ESTERS AND DIMETHYLACETALS FROM LIPIDS WITH BORON FLUORIDE--METHANOL

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24506864

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2013.11.023

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24506864 AND SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24506864 AND SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

24506864

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24506864 AND SRC:MED&resulttype=core&format=json