The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals (Q27013823)

R. Yuan

series ordinal

2

1 reference

K. L. Lunetta

series ordinal

3

1 reference

language of work or name

1 reference

May 2012

1 reference

The Journals of Gerontology

published in

1 reference

volume

67

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issue

5

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page(s)

470-9

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Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

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Association of FOXO3A variation with human longevity confirmed in German centenarians

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FOXO3A genotype is strongly associated with human longevity

21 March 2017

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Role of Genes and Environments for Explaining Alzheimer Disease

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Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts

21 March 2017

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

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Multipoint Quantitative-Trait Linkage Analysis in General Pedigrees

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28 September 2017

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28 September 2017

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Challenges of Translating Basic Research Into Therapeutics: Resveratrol as an Example

28 September 2017

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Successful aging shows linkage to chromosomes 6, 7, and 14 in the Amish

28 September 2017

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Predictors of Extraordinary Survival in the Iowa Established Populations for Epidemiologic Study of the Elderly: Cohort Follow-Up to “Extinction”

28 September 2017

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Frailty phenotypes in the elderly based on cluster analysis: a longitudinal study of two Danish cohorts. Evidence for a genetic influence on frailty

28 September 2017

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Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

28 September 2017

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Mice as a mammalian model for research on the genetics of aging

28 September 2017

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Health and function of participants in the Long Life Family Study: A comparison with other cohorts

28 September 2017

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Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

28 September 2017

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Genetic Studies Reveal the Role of the Endocrine and Metabolic Systems in Aging

28 September 2017

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Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity

28 September 2017

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Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

28 September 2017

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28 September 2017

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Identification of genetic determinants of IGF‐1 levels and longevity among mouse inbred strains

28 September 2017

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Genome-wide analysis of genetic loci associated with Alzheimer disease

28 September 2017

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The effect of maintaining cognition on risk of disability and death

28 September 2017

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A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

28 September 2017

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Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

28 September 2017

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Epigenetic factors in aging and longevity

28 September 2017

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A new standard genetic map for the laboratory mouse

28 September 2017

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Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

28 September 2017

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Loci at chromosomes 13, 19 and 20 influence age at natural menopause

28 September 2017

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Practical applications of the bioinformatics toolbox for narrowing quantitative trait loci

28 September 2017

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Successful skeletal aging: a marker of low fracture risk and longevity. The Study of Osteoporotic Fractures (SOF).

28 September 2017

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A physiologic index of comorbidity: relationship to mortality and disability

28 September 2017

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Exceptional longevity in men: modifiable factors associated with survival and function to age 90 years.

28 September 2017

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Quantitative trait loci define genes and pathways underlying genetic variation in longevity

28 September 2017

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The quest for genetic determinants of human longevity: challenges and insights

28 September 2017

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28 September 2017

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Clinical phenotype of families with longevity.

28 September 2017

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Heritability and validity of healthy physical aging (wellness) in elderly male twins.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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31 May 2018

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The contribution of genetic influences to measures of lower-extremity function in older male twins

31 May 2018

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Longevity is moderately heritable in a sample of Danish twins born 1870-1880.

31 May 2018

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Genetic associations with human longevity at the APOE and ACE loci

31 May 2018

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Cardiovascular risk factors predictive for survival and morbidity-free survival in the oldest-old Framingham Heart Study participants

31 May 2018

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Siblings of Okinawan centenarians share lifelong mortality advantages

21 January 2018

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Lower all-cause, cardiovascular, and cancer mortality in centenarians' offspring

21 January 2018

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Favorable glucose tolerance and lower prevalence of metabolic syndrome in offspring without diabetes mellitus of nonagenarian siblings: the Leiden longevity study

21 January 2018

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The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870–1900

21 January 2018

1 reference

https://api.crossref.org/works/10.1093/GERONA/GLS089

Heritability of life span in the Old Order Amish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093/GERONA/GLS089

Familial excess longevity in Utah genealogies.

21 January 2018

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https://api.crossref.org/works/10.1093/GERONA/GLS089

Genetic and environmental influences on functional abilities in Danish twins aged 75 years and older

21 January 2018

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Genetic contribution to rate of change in functional abilities among Danish twins aged 75 years or more

21 January 2018

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A Twin Study on the Heritability of Walking Ability Among Older Women

21 January 2018

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Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: the Framingham Study

21 January 2018

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https://api.crossref.org/works/10.1093/GERONA/GLS089

Estimation of variance components for age at menarche in twin families

21 January 2018

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Genetic influence on human lifespan and longevity

21 January 2018

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A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals

21 January 2018

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https://api.crossref.org/works/10.1093/GERONA/GLS089

Association study on long-living individuals from Southern Italy identifies rs10491334 in the CAMKIV gene that regulates survival proteins.

21 January 2018

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https://api.crossref.org/works/10.1093/GERONA/GLS089

Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

21 January 2018

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https://api.crossref.org/works/10.1093/GERONA/GLS089

Apolipoprotein e genotypes: relationship to cognitive functioning, cognitive decline, and survival in nonagenarians

21 January 2018

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Quantitative trait loci for insulin-like growth factor I, leptin, thyroxine, and corticosterone in genetically heterogeneous mice

21 January 2018

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Heritability of Age at Natural Menopause in the Framingham Heart Study

21 January 2018

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https://api.crossref.org/works/10.1093/GERONA/GLS089

Genetic influences and grip strength norms in the NHLBI twin study males aged 59–69

21 January 2018

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https://api.crossref.org/works/10.1093/GERONA/GLS089

Hand grip strength: A phenotype suitable for identifying genetic variants affecting mid- and late-life physical functioning

21 January 2018

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https://api.crossref.org/works/10.1093/GERONA/GLS089

A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease

21 January 2018

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Non-familial Alzheimer's disease is mainly due to genetic factors.

28 November 2018

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Stability and change in genetic and environmental influences on hand-grip strength in older male twins

28 November 2018

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Midlife risk factors and healthy survival in men

28 November 2018

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12 December 2020

Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci

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12 December 2020

Age, gender, and body mass effects on quantitative trait loci for bone mineral density: the Framingham Study

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12 December 2020

Familial mortality in the Utah population database: characterizing a human aging phenotype

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12 December 2020

Heritability of menopausal age in mothers and daughters

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12 December 2020

Genetic influences on life span and survival among elderly African-Americans, Caribbean Hispanics, and Caucasians

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12 December 2020

Estimation of apolipoprotein E genotype-specific relative mortality risks from the distribution of genotypes in centenarians and middle-aged men: apolipoprotein E gene is a "frailty gene," not a "longevity gene"

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12 December 2020

A Guttman health scale for the aged

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12 December 2020

Exceptional familial clustering for extreme longevity in humans

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1093/GERONA/GLS089

1 reference

1 reference

1 reference

PubMed publication ID

22499766

1 reference