Targeting survivin in cancer (Q27012954)

Crossref

language of work or name

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28 May 2013

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332

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issue

2

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page(s)

225-8

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First-in-class, first-in-human phase I results of targeted agents: highlights of the 2008 American society of clinical oncology meeting

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Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together

21 March 2017

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Solution structure of human survivin and its binding interface with Smac/Diablo

21 March 2017

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The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly

21 March 2017

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Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis

21 March 2017

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A p34(cdc2) survival checkpoint in cancer

21 March 2017

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Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics

21 March 2017

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Targeting survivin in cancer therapy

21 March 2017

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Nuclear and cytoplasmic survivin: molecular mechanism, prognostic, and therapeutic potential

21 March 2017

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Survivin-derived peptide epitopes and their role for induction of antitumor immunity in hematological malignancies

21 March 2017

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A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

21 March 2017

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 March 2017

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Chromosomal passengers: conducting cell division

7 April 2017

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Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights

7 April 2017

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Survivin as a global target of intrinsic tumor suppression networks

28 September 2017

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Survivin: a new target for anti-cancer therapy

28 September 2017

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Phase I study of YM155, a novel survivin suppressant, in patients with advanced solid tumors

28 September 2017

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BCL-2 family antagonists for cancer therapy

28 September 2017

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Phase I and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin.

28 September 2017

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SPC3042: a proapoptotic survivin inhibitor.

28 September 2017

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Therapeutic dendritic cell vaccination of patients with metastatic renal cell carcinoma: a clinical phase 1/2 trial

28 September 2017

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Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis

28 September 2017

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28 September 2017

IAPs: what's in a name?

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Phase I clinical trial of repeat dose terameprocol vaginal ointment in healthy female volunteers

28 September 2017

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Terameprocol, a novel site-specific transcription inhibitor with anticancer activity.

28 September 2017

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Cancer treatment: the combination of vaccination with other therapies

28 September 2017

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Compartmentalized phosphorylation of IAP by protein kinase A regulates cytoprotection

28 September 2017

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A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension

28 September 2017

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Microtubule capture: a concerted effort.

28 September 2017

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The case for Survivin as mitotic regulator

28 September 2017

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Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

28 September 2017

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Role of the Survivin gene in pathophysiology

28 September 2017

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Survivin, a cancer target with an emerging role in normal adult tissues

28 September 2017

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Survivin modulates microtubule dynamics and nucleation throughout the cell cycle

28 September 2017

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Innovation: Rescuing drug discovery: in vivo systems pathology and systems pharmacology

28 September 2017

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Systemic treatment with tetra-O-methyl nordihydroguaiaretic acid suppresses the growth of human xenograft tumors

28 September 2017

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Rational design of shepherdin, a novel anticancer agent.

28 September 2017

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A potent immunogenic general cancer vaccine that targets survivin, an inhibitor of apoptosis proteins.

28 September 2017

1 reference

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Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression

28 September 2017

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Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1).

28 September 2017

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Full-length dominant-negative survivin for cancer immunotherapy.

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Regulation of survivin function by Hsp90

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Survivin is a shared tumor-associated antigen expressed in a broad variety of malignancies and recognized by specific cytotoxic T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

A role for survivin in chemoresistance of endothelial cells mediated by VEGF

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Control of apoptosis during angiogenesis by survivin expression in endothelial cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

AACR-NCI-EORTC--21st International Symposium. Molecular targets and cancer therapeutics--Part 1.

28 September 2017

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Phase I/II clinical safety studies of terameprocol vaginal ointment

31 May 2018

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Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial

31 May 2018

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Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients.

28 November 2018

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The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Survivin, cancer networks and pathway-directed drug discovery.

28 November 2018

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YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts

28 November 2018

1 reference

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Why is cancer drug discovery so difficult?

28 November 2018

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Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Complete remission of liver metastasis of pancreatic cancer under vaccination with a HLA-A2 restricted peptide derived from the universal tumor antigen survivin

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Induction of antitumour immunity using survivin peptide-pulsed dendritic cells in a murine lymphoma model

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Survivin and molecular pathogenesis of colorectal cancer.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3695618

Antibody response to the tumor-associated inhibitor of apoptosis protein survivin in cancer patients

28 November 2018

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12 December 2020

Generation of survivin-specific CD8 T effector cells by dendritic cells pulsed with protein or selected peptides

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12 December 2020

The apoptosis inhibitor protein survivin induces tumor-specific CD8 and CD4 T cells in colorectal cancer patients

1 reference

12 December 2020

Multicenter phase II trial of YM155, a small-molecule suppressor of survivin, in patients with advanced, refractory, non-small-cell lung cancer

1 reference

12 December 2020

A multi-center phase II evaluation of the small molecule survivin suppressor YM155 in patients with unresectable stage III or IV melanoma

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12 December 2020

Regulation of mitochondrial Smac/DIABLO-selective release by survivin

1 reference

12 December 2020