Opioid receptor heteromers in analgesia (Q27004306)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

28 January 2020

title

Opioid receptor heteromers in analgesia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

28 January 2020

0 references

Cristina Maria Costantino

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Ivone Gomes

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

28 January 2020

Steven D Stockton

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

28 January 2020

Maribel P Lim

4

1 reference

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28 January 2020

Lakshmi A Devi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

1 reference

10 April 2012

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

Expert Reviews in Molecular Medicine

28 January 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

28 January 2020

volume

14

2 references

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28 January 2020

page(s)

e9

2 references

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GPCR oligomers in pharmacology and signaling

28 January 2020

cites work

1 reference

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Allostery at G Protein-Coupled Receptor Homo- and Heteromers: Uncharted Pharmacological Landscapes

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Receptor heteromerization and drug discovery

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G-protein-coupled receptor heterodimerization modulates receptor function

21 March 2017

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Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons

21 March 2017

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Heterodimerization of mu and delta opioid receptors: A role in opiate synergy

21 March 2017

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Enhanced morphine analgesia in mice lacking beta-arrestin 2

21 March 2017

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21 March 2017

7 January 2021

inferred from DOI database lookup

Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia

1 reference

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Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers

21 March 2017

1 reference

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mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis

21 March 2017

1 reference

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Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

21 March 2017

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Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia

21 March 2017

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Molecular basis of long-term plasticity underlying addiction

21 March 2017

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G protein-coupled receptor heteromerization: a role in allosteric modulation of ligand binding

7 April 2017

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Exploring a role for heteromerization in GPCR signalling specificity

28 September 2017

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Escorts take the lead molecular chaperones as therapeutic targets

28 September 2017

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Disruption of morphine-conditioned place preference by a delta2-opioid receptor antagonist: study of mu-opioid and delta-opioid receptor expression at the synapse

28 September 2017

1 reference

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Coexpression of delta- and mu-opioid receptors in nociceptive sensory neurons.

28 September 2017

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Cannabinoid-opioid interactions during neuropathic pain and analgesia

28 September 2017

1 reference

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Marijuana craving in the brain

28 September 2017

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Dissociation of the opioid receptor mechanisms that control mechanical and heat pain

28 September 2017

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mu-Opioid receptor forms a functional heterodimer with cannabinoid CB1 receptor: electrophysiological and FRET assay analysis.

28 September 2017

1 reference

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Delta-opioid receptor antagonists prevent sensitization to the conditioned rewarding effects of morphine

28 September 2017

1 reference

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Cell surface targeting of mu-delta opioid receptor heterodimers by RTP4.

28 September 2017

1 reference

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Opioid receptors: from binding sites to visible molecules in vivo

28 September 2017

1 reference

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Advances in the field of cannabinoid--opioid cross-talk

28 September 2017

1 reference

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The other side of the opioid story: modulation of cell growth and survival signaling.

28 September 2017

1 reference

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Recent advances and perceptions in studies of heterodimerization between G protein-coupled receptors

28 September 2017

1 reference

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Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy

28 September 2017

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Modulation of extracellular signal-regulated kinase (ERK) by opioid and cannabinoid receptors that are expressed in the same cell

28 September 2017

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Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo

28 September 2017

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Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series

28 September 2017

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Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems

28 September 2017

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Opioid receptor homo- and heterodimerization in living cells by quantitative bioluminescence resonance energy transfer

28 September 2017

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Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions.

28 September 2017

1 reference

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28 September 2017

1 reference

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A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia

28 September 2017

1 reference

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Opioid Receptor Oligomerization: Detection and Functional Characterization of Interacting Receptors

28 September 2017

1 reference

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Antinociceptive synergy between delta(9)-tetrahydrocannabinol and opioids after oral administration

28 September 2017

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Descending modulation in persistent pain: an update

28 September 2017

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Chronic pain and medullary descending facilitation

28 September 2017

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Exploring the opioid system by gene knockout

28 September 2017

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Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization

28 September 2017

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Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal

28 September 2017

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G protein coupled receptor dimerization: implications in modulating receptor function

28 September 2017

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28 September 2017

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Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene

28 September 2017

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28 September 2017

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Regulation of adenylate cyclase by chronic exposure to cannabimimetic drugs

28 September 2017

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28 September 2017

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Delta 9-tetrahydrocannabinol produces naloxone-blockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Increased abundance of opioid receptor heteromers after chronic morphine administration

28 September 2017

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Delta receptors are required for full inhibitory coupling of mu-receptors to voltage-dependent Ca(2 ) channels in dorsal root ganglion neurons

31 May 2018

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Chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid CB(1) receptor binding and mRNA levels

31 May 2018

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Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice

31 May 2018

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Independence of, and interactions between, cannabinoid and opioid signal transduction pathways in N18TG2 cells

31 May 2018

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Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor.

31 May 2018

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Morphine allosterically modulates the binding of [3H]leucine enkephalin to a particulate fraction of rat brain

31 May 2018

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Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice

31 May 2018

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Spinal administration of lipoxygenase inhibitors suppresses behavioural and neurochemical manifestations of naloxone-precipitated opioid withdrawal

31 May 2018

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An emerging role for the delta opioid receptor in the regulation of mu opioid receptor function.

21 January 2018

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Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation.

21 January 2018

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Neuronal types expressing mu- and delta-opioid receptor mRNA in the rat hippocampal formation

21 January 2018

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Rescuing the traffic-deficient mutants of rat mu-opioid receptors with hydrophobic ligands

21 January 2018

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Distinct subcellular distribution of delta-opioid receptor fused with various tags in PC12 cells

21 January 2018

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Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties

21 January 2018

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The involvement of VEGF receptors and MAPK in the cannabinoid potentiation of Ca2 flux into N18TG2 neuroblastoma cells

21 January 2018

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Dual ultrastructural immunocytochemical labeling of μ and δ opioid receptors in the superficial layers of the rat cervical spinal cord

21 January 2018

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Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism

21 January 2018

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Morphine and pain-related stimuli enhance cell surface availability of somatic delta-opioid receptors in rat dorsal root ganglia.

21 January 2018

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Mu and delta receptors: Their role in analgesia and in the differential effects of opioid peptides on analgesia

21 January 2018

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CB1-cannabinoid and mu-opioid receptor co-localization on postsynaptic target in the rat dorsal horn

21 January 2018

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The effects of receptor selective opioid peptides on morphine-induced analgesia

21 January 2018

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Central glucocorticoid receptors modulate the expression of spinal cannabinoid receptors induced by chronic morphine exposure

21 January 2018

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Evidence for a bidirectional cross-tolerance between morphine and delta 9-tetrahydrocannabinol in mice

21 January 2018

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Region-dependent changes in endocannabinoid transmission in the brain of morphine-dependent rats

21 January 2018

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Cannabinoid withdrawal syndrome is reduced in double mu and delta opioid receptor knockout mice.

21 January 2018

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Delta9-tetrahydrocannabinol releases and facilitates the effects of endogenous enkephalins: reduction in morphine withdrawal syndrome without change in rewarding effect

21 January 2018

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CB1 cannabinoid receptor antagonist-induced opiate withdrawal in morphine-dependent rats

21 January 2018

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Potentiation of delta 9-tetrahydrocannabinol-induced analgesia by morphine in mice: involvement of mu- and kappa-opioid receptors

21 January 2018

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Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype

21 January 2018

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Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice

21 January 2018

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Cannabinoid receptor and WIN 55 212‐2‐stimulated [35S]‐GTPγS binding in the brain of mu‐, delta‐ and kappa‐opioid receptor knockout mice

21 January 2018

1 reference

Development of antinociceptive tolerance and physical dependence following morphine i.c.v. infusion in mice

21 January 2018

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Absence of conditioned place preference or reinstatement with bivalent ligands containing mu-opioid receptor agonist and delta-opioid receptor antagonist pharmacophores

21 January 2018

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Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice

21 January 2018

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Compartment-specific localization of cannabinoid 1 (CB1) and mu-opioid receptors in rat nucleus accumbens

21 January 2018

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Interaction with vesicle luminal protachykinin regulates surface expression of delta-opioid receptors and opioid analgesia

21 January 2018

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Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice.

21 January 2018

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Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors.

28 November 2018

1 reference

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Prolonged morphine treatment targets delta opioid receptors to neuronal plasma membranes and enhances delta-mediated antinociception.

28 November 2018

1 reference

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Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice

28 November 2018

1 reference

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Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus.

28 November 2018

1 reference

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Localization of cannabinoid CB(1) receptor mRNA in neuronal subpopulations of rat striatum: a double-label in situ hybridization study

28 November 2018

1 reference

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Enhancement mu opioid antinociception by oral delta9-tetrahydrocannabinol: dose-response analysis and receptor identification.

28 November 2018

1 reference

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Mu- and delta-opioid receptor mRNAs are expressed in spinally projecting serotonergic and nonserotonergic neurons of the rostral ventromedial medulla

28 November 2018

1 reference

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Time-course of the cannabinoid receptor down-regulation in the adult rat brain caused by repeated exposure to delta9-tetrahydrocannabinol

28 November 2018

1 reference

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Mechanisms of β-Adrenergic Receptor Desensitization and Resensitization

28 November 2018

1 reference

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Chronic treatment with a synthetic cannabinoid CP-55,940 alters G-protein expression in the rat central nervous system

28 November 2018

1 reference

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Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement

28 November 2018

1 reference

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Potentiation of opiate action in neuroblastoma N18TG2 cells by lipid incorporation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805500

A protein-lipid model of the opiate receptor

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22490239

12 December 2020

inferred from PubMed ID database lookup

Allosteric modulation by leucine-enkephalin of [3H]naloxone binding in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/22490239

12 December 2020

inferred from PubMed ID database lookup

Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22490239

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1017/ERM.2012.5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

release_5jaxfms2jfbfflvykeopfdr6mm

28 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5jaxfms2jfbfflvykeopfdr6mm

24 November 2022

mapped directly with Wikidata item

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22490239 AND SRC:MED&resulttype=core&format=json