Xenobiotic perturbation of ER stress and the unfolded protein response (Q26998690)

J. L. Stevens

series ordinal

2

1 reference

J. W. Lawrence

series ordinal

3

1 reference

language of work or name

1 reference

February 2013

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published in

Toxicologic Pathology

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volume

41

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issue

2

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page(s)

235-62

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The dsRNA protein kinase PKR: virus and cell control

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK

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Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain

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Oxidative protein folding in eukaryotes: mechanisms and consequences

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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

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CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

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Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

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Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase

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XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

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Inhibition of hepatic carnitine palmitoyl-transferase I (CPT IA) by valproyl-CoA as a possible mechanism of valproate-induced steatosis

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Activating transcription factor 4.

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Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease

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An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses

21 January 2018

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The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.

21 January 2018

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Modulating the endoplasmic reticulum stress response with trans-4,5-dihydroxy-1,2-dithiane prevents chemically induced renal injury in vivo

21 January 2018

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Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

21 January 2018

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The unfolded protein response in health and disease

21 January 2018

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Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (P

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Cyclosporine triggers endoplasmic reticulum stress in endothelial cells: a role for endothelial phenotypic changes and death

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Regulation of ER stress proteins by valproate: therapeutic implications.

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells.

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL.

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Assays for detecting the unfolded protein response.

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

A review of the mammalian unfolded protein response.

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

SUMO modification regulates the transcriptional activity of XBP1

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Apigenin protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Baicalein protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis through inhibition of reactive oxygen species production and CHOP induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress in proteinuric kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

β-Adrenergic receptor stimulation induces endoplasmic reticulum stress in adult cardiac myocytes: role in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Luman is capable of binding and activating transcription from the unfolded protein response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Setting the standards: quality control in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The heat shock factor family and adaptation to proteotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Upregulation and overexpression of human X-box binding protein 1 (hXBP-1) gene in primary breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The unfolded protein response is an important regulator of inflammatory genes in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

SIRT1 associates with eIF2-alpha and regulates the cellular stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Heat shock protein 72 protects insulin-secreting beta cells from lipopolysaccharide-induced endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Mitochondrial calcium signaling driven by the IP3 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The mitochondrial UPR - protecting organelle protein homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1177/0192623312470764

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Activation of the unfolded protein response is an early event in Alzheimer's and Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Activation of ATF4 mediates unwanted Mcl-1 accumulation by proteasome inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

XBP1 Controls Maturation of Gastric Zymogenic Cells by Induction of MIST1 and Expansion of the Rough Endoplasmic Reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress in the kidney as a novel mediator of kidney injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress as a progression factor for kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Bax inhibitor-1: a highly conserved endoplasmic reticulum-resident cell death suppressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Mechanisms of hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Wolcott-Rallison syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Valproate, a mood stabilizer, induces WFS1 expression and modulates its interaction with ER stress protein GRP94

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Human immunodeficiency virus protease inhibitors modulate Ca2 homeostasis and potentiate alcoholic stress and injury in mice and primary mouse and human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress and liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The unfolded protein response in nutrient sensing and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

A molecular chaperone inducer protects neurons from ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Caspases and kinases in a death grip

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Ryanodine receptors: structure, expression, molecular details, and function in calcium release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

p38 MAPK–mediated regulation of Xbp1s is crucial for glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

IRE1 signaling affects cell fate during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Divergent effects of PERK and IRE1 signaling on cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Implication of unfolded protein response in resveratrol-induced inhibition of K562 cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic Reticulum Chaperones GRP78 and Calreticulin Prevent Oxidative Stress, Ca2 Disturbances, and Cell Death in Renal Epithelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin-induced apoptosis in human nasopharyngeal carcinoma CNE cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ER chaperone functions during normal and stress conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The endoplasmic reticulum and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Up regulation of the GRP-78 and GADD-153 and down regulation of Bcl-2 proteins in primary glomerular diseases: a possible involvement of the ER stress pathway in glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

A diversity of SERCA Ca2 pump inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

cis-acting sequences involved in the translational control of GCN4 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Drug-related hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Protein import into mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Translocation of proteins into mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

JAB1 participates in unfolded protein responses by association and dissociation with IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Measuring ER Stress and the Unfolded Protein Response Using Mammalian Tissue Culture System

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Role of endoplasmic reticulum stress in metabolic disease and other disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Cyclosporine-induced endoplasmic reticulum stress triggers tubular phenotypic changes and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Effect on tumor cells of blocking survival response to glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Proteasome inhibitor MG132-induced apoptosis via ER stress-mediated apoptotic pathway and its potentiation by protein tyrosine kinase p56lck in human Jurkat T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Sensing Endoplasmic Reticulum Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ER stress triggers apoptosis by activating BH3-only protein Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

An integrative overview on the mechanisms underlying the renal tubular cytotoxicity of gentamicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Mitochondrial permeability transition in Ca2 -dependent apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Ca(2 ) transfer from the ER to mitochondria: when, how and why

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Bax inhibitor 1 in apoptosis and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

N-glycan processing in ER quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Proapoptotic BAX and BAK control multiple initiator caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Regulation of autophagy by ATF4 in response to severe hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Caspases: Intracellular Signaling by Proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Heterotrimerization of heat-shock factors 1 and 2 provides a transcriptional switch in response to distinct stimuli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Oxidized low-density lipoproteins trigger endoplasmic reticulum stress in vascular cells: prevention by oxygen-regulated protein 150 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

How an inhibitor of the HIV-I protease modulates proteasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Mechanisms of ER Stress-Induced Apoptosis in Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

RNA-mediated response to heat shock in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The antioxidant edaravone attenuates ER-stress-mediated cardiac apoptosis and dysfunction in rats with autoimmune myocarditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Quality control of mitochondria: protection against neurodegeneration and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress as a novel therapeutic target in heart diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ER stress controls iron metabolism through induction of hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Sodium 4-phenylbutyrate protects against liver ischemia reperfusion injury by inhibition of endoplasmic reticulum-stress mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Membrane biogenesis during B cell differentiation: most endoplasmic reticulum proteins are expressed coordinately

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Salubrinal, an eIF2α dephosphorylation inhibitor, enhances cisplatin-induced oxidative stress and nephrotoxicity in a mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress: cell life and death decisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Hyperthermia Induces the ER Stress Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERK

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Presence of the functional CASPASE‐12 allele in Indian subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Activation of JNK and transcriptional repressor ATF3/LRF1 through the IRE1/TRAF2 pathway is implicated in human vascular endothelial cell death by homocysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

From endoplasmic-reticulum stress to the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Small molecule regulators of autophagy identified by an image-based high-throughput screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Measurement of ER stress response and inflammation in the mouse model of nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

Activation of the unfolded protein response and alternative splicing of ATF6α in HLA-B27 positive lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/0192623312470764

21 January 2018

Identifiers

DOI

10.1177/0192623312470764

1 reference

release_uqui6ttlzndybjkiqrqwcl5qz4

Fatcat ID

0 references

PubMed publication ID

23334697

1 reference