Principles of allosteric interactions in cell signaling (Q26996431)

Journal of the American Chemical Society

Crossref

language of work or name

1 reference

24 December 2014

2 references

26 August 2020

2 references

26 August 2020

136

1 reference

issue

51

1 reference

page(s)

17692-701

1 reference

Allostery in disease and in drug discovery

cites work

1 reference

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Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis

21 March 2017

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NMR insights into protein allostery

21 March 2017

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Dynamic protein–DNA recognition: beyond what can be seen

21 March 2017

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Cell signaling by receptor tyrosine kinases

21 March 2017

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Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

21 March 2017

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Conformational switch of syntaxin-1 controls synaptic vesicle fusion

21 March 2017

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Exploring the folding landscape of a structured RNA

21 March 2017

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The role of distant mutations and allosteric regulation on LovD active site dynamics

21 March 2017

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Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis

21 March 2017

1 reference

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Structure and dynamics of the ATP-bound open conformation of Hsp70 chaperones

21 March 2017

1 reference

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Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

21 March 2017

1 reference

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An ATP-site on-off switch that restricts phosphatase accessibility of Akt

21 March 2017

1 reference

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Hidden alternative structures of proline isomerase essential for catalysis

21 March 2017

1 reference

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Directed Evolution and Structural Characterization of a Simvastatin Synthase

21 March 2017

1 reference

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Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78

21 March 2017

1 reference

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Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate

21 March 2017

1 reference

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DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

How potassium affects the activity of the molecular chaperone Hsc70. II. Potassium binds specifically in the ATPase active site

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Protein sectors: evolutionary units of three-dimensional structure

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

From Levinthal to pathways to funnels

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

The two-state model of receptor activation

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

A unified view of "how allostery works"

21 March 2017

1 reference

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Hot spots for allosteric regulation on protein surfaces

21 March 2017

1 reference

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

21 March 2017

1 reference

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The role of dynamic conformational ensembles in biomolecular recognition

7 April 2017

1 reference

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Evolutionarily conserved pathways of energetic connectivity in protein families

7 April 2017

1 reference

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Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism

7 April 2017

1 reference

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Identifying key residues for protein allostery through rigid residue scan

9 May 2017

1 reference

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The structural basis for cancer treatment decisions

28 September 2017

1 reference

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Unraveling structural mechanisms of allosteric drug action

28 September 2017

1 reference

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Free energy diagrams for protein function

28 September 2017

1 reference

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Functional anatomy of an allosteric protein

28 September 2017

1 reference

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Multiple conformational selection and induced fit events take place in allosteric propagation.

28 September 2017

1 reference

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Allosteric conformational barcodes direct signaling in the cell

28 September 2017

1 reference

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Microscopic insights into the NMR relaxation-based protein conformational entropy meter

28 September 2017

1 reference

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The allosteric communication pathways in KIX domain of CBP

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

The spatial structure of cell signaling systems

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Dynamic fluctuations provide the basis of a conformational switch mechanism in apo cyclic AMP receptor protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

The underappreciated role of allostery in the cellular network.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Probing allostery through DNA

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

The dark energy of proteins comes to light: conformational entropy and its role in protein function revealed by NMR relaxation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

The role of allostery in the ubiquitin-proteasome system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allosteric communication across the native and mutated KIT receptor tyrosine kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allosteric post-translational modification codes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allosteric inhibition of individual enzyme molecules trapped in lipid vesicles.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Conformational control of the binding of the transactivation domain of the MLL protein and c-Myb to the KIX domain of CREB

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

IκB kinase regulation of the TPL-2/ERK MAPK pathway

28 September 2017

1 reference

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Allosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra-molecular communication pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

PSCDB: a database for protein structural change upon ligand binding

28 September 2017

1 reference

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Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies

28 September 2017

1 reference

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Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity.

28 September 2017

1 reference

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Computational modeling of allosteric communication reveals organizing principles of mutation-induced signaling in ABL and EGFR kinases

28 September 2017

1 reference

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Change in allosteric network affects binding affinities of PDZ domains: analysis through perturbation response scanning

28 September 2017

1 reference

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Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors

28 September 2017

1 reference

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Flexible cullins in cullin-RING E3 ligases allosterically regulate ubiquitination

28 September 2017

1 reference

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Gene-specific transcription activation via long-range allosteric shape-shifting

28 September 2017

1 reference

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Regulation of the catalytic activity of the EGF receptor.

28 September 2017

1 reference

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Dynamic allostery: linkers are not merely flexible

28 September 2017

1 reference

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Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of LRP-1 leads to sustained ERK phosphorylation via dow

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Mapping allostery through the covariance analysis of NMR chemical shifts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Protein dynamics and allostery: an NMR view

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

NRF2, cancer and calorie restriction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Energy landscapes as a tool to integrate GPCR structure, dynamics, and function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allosteric supramolecular triple-layer catalysts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allostery and population shift in drug discovery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Identification of an Allosteric Signaling Network within Tec Family Kinases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Protein functional landscapes, dynamics, allostery: a tortuous path towards a universal theoretical framework.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

The role of conformational entropy in molecular recognition by calmodulin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

p53-family proteins and their regulators: hubs and spokes in tumor suppression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Hormone binding and co-regulator binding to the glucocorticoid receptor are allosterically coupled

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Molecular dynamics reveal the essential role of linker motions in the function of cullin-RING E3 ligases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Mechanisms of transcription factor selectivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

The mechanism of ubiquitination in the cullin-RING E3 ligase machinery: conformational control of substrate orientation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

'7TM receptor allostery: putting numbers to shapeshifting proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Measurement of methyl group motional parameters of invisible, excited protein states by NMR spectroscopy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

The origin of allosteric functional modulation: multiple pre-existing pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

DNA-binding specificity and in vivo targets of Caenorhabditis elegans nuclear factor I.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Inhibitor hijacking of Akt activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Controlling proteins through molecular springs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Frameworks for understanding long-range intra-protein communication

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Visualizing lowly-populated regions of the free energy landscape of macromolecular complexes by paramagnetic relaxation enhancement

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allosteric regulation and catalysis emerge via a common route.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allostery and cooperativity revisited

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

28 September 2017

Energy flow in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allostery: absence of a change in shape does not imply that allostery is not at play

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Probing invisible, low-populated States of protein molecules by relaxation dispersion NMR spectroscopy: an application to protein folding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allosteric effects in the marginally stable von Hippel-Lindau tumor suppressor protein and allostery-based rescue mutant design

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Signal amplification by allosteric catalysis.

28 September 2017

1 reference

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The role of DNA response elements as allosteric modulators of steroid receptor function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Functional dynamics of PDZ binding domains: a normal-mode analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Is allostery an intrinsic property of all dynamic proteins?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Mechanism of the nuclear receptor molecular switch

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Structured disorder and conformational selection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Molecular recognition by induced fit: how fit is the concept?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Two classes of androgen receptor elements mediate cooperativity through allosteric interactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Folding and binding cascades: dynamic landscapes and population shifts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Folding funnels and binding mechanisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Folding and binding cascades: shifts in energy landscapes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Folding funnels, binding funnels, and protein function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Estrogen response elements function as allosteric modulators of estrogen receptor conformation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Navigating the folding routes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allosterically tunable, DNA-based switches triggered by heavy metals.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

An interdomain energetic tug-of-war creates the allosterically active state in Hsp70 molecular chaperones

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Using distal-site mutations and allosteric inhibition to tune, extend, and narrow the useful dynamic range of aptamer-based sensors.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Evolving a robust signal transduction pathway from weak cross-talk

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

p53 activates transcription by directing structural shifts in Mediator

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Transient non-native hydrogen bonds promote activation of a signaling protein

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Surface sites for engineering allosteric control in proteins

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Using the population-shift mechanism to rationally introduce "Hill-type" cooperativity into a normally non-cooperative receptor

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Evolutionarily distinct versions of the multidomain enzyme α-isopropylmalate synthase share discrete mechanisms of V-type allosteric regulation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Atomistic kinetic model for population shift and allostery in biomolecules

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Allo-network drugs: harnessing allostery in cellular networks

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

During transitions proteins make fleeting bonds.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Intramolecular signaling pathways revealed by modeling anisotropic thermal diffusion

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Modeling the functional effects of allosteric modulators at pharmacological receptors: an extension of the two-state model of receptor activation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291754

Molecular basis for the pH dependent structural transition of Nitrophorin 4

28 November 2018

1 reference

12 December 2020

Allosteric Effects Govern Nuclear Receptor Action: DNA Appears as a Player

1 reference

12 December 2020

Identification of specificity and promiscuity of PDZ domain interactions through their dynamic behavior

1 reference

12 December 2020

Pump-probe molecular dynamics as a tool for studying protein motion and long range coupling

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA510028C

1 reference

1 reference

1 reference

PubMed publication ID

25474128

1 reference