Insights into the antimicrobial properties of hepcidins: advantages and drawbacks as potential therapeutic agents (Q26991996)

21 May 2022

Insights into the antimicrobial properties of hepcidins: advantages and drawbacks as potential therapeutic agents (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

antimicrobial cationic peptides

13 May 2020

main subject

1 reference

27 September 2020

1 reference

25867823

bacteria

1 reference

25867823

Hepcidins

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

Giovanna Batoni

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

Arianna Tavanti

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

author name string

Giuseppantonio Maisetta

series ordinal

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

language of work or name

1 reference

10 April 2015

3 references

27 September 2020

21 May 2022

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

27 September 2020

20

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

issue

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

page(s)

6319-6341

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

Creative Commons Attribution

13 May 2020

copyright license

2 references

27 September 2020

21 May 2022

0 references

Resistance to antibiotics: are we in the post-antibiotic era?

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

A call for antibiotic alternatives research

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Characterization of Antimicrobial Peptides toward the Development of Novel Antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

The development of antimicrobial peptides as new antibacterial drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Multifunctional cationic host defence peptides and their clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antimicrobial peptides of multicellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Peptide antimicrobial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Cationic host defense (antimicrobial) peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Host defence peptides from invertebrates--emerging antimicrobial strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Cationic peptides: effectors in innate immunity and novel antimicrobials

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antibacterial peptides for therapeutic use: obstacles and realistic outlook

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antimicrobial peptides for therapeutic applications: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Mechanisms of antimicrobial peptide action and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

The expanding scope of antimicrobial peptide structures and their modes of action

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Role of lipids in the interaction of antimicrobial peptides with membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Alpha-helical cationic antimicrobial peptides: relationships of structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Peptide antimicrobials: cell wall as a bacterial target

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antimicrobial activity of human hepcidin 20 and 25 against clinically relevant bacterial strains: effect of copper and acidic pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

pH-dependent disruption of Escherichia coli ATCC 25922 and model membranes by the human antimicrobial peptides hepcidin 20 and 25.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Active internalization of the Penicillium chrysogenum antifungal protein PAF in sensitive aspergilli.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaperone-assisted protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antimicrobial peptides: general overview and clinical implications in human health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Expression and regulation of antimicrobial peptides in the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Inducing endogenous antimicrobial peptides to battle infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Host defense peptides in wound healing.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Therapeutic potential of HDPs as immunomodulatory agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Bacteriostatic activity of the proregion of human hepcidin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Cloning, sequencing and expression analysis of the equine hepcidin gene by real-time PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Buffalo hepcidin: characterization of cDNA and study of antimicrobial property

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Molecular characterization of a novel hepcidin (HepcD) from Camelus dromedarius. Synthetic peptide forms exhibit antibacterial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Identification, characterization and expression analysis of hepcidin gene in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Molecular evolution and characterization of hepcidin gene products in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Pharmacokinetics of gallium maltolate after intragastric administration in neonatal foals

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Use of serum amyloid A and other acute phase reactants to monitor the inflammatory response after castration in horses: a field study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

The antimicrobial peptide hepcidin exerts an important role in the innate immunity against bacteria in the bony fish gilthead seabream.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Importance of the disulfide bridges in the antibacterial activity of human hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

RETRACTED: The hepcidin-binding site on ferroportin is evolutionarily conserved

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

In vitro reactive oxygen species production by histatins and copper(I,II).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Structure-activity relation of human beta-defensin 3: influence of disulfide bonds and cysteine substitution on antimicrobial activity and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

SELDI-TOF MS detection of urinary hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Immunoassay for human serum hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Enhanced membrane disruption and antibiotic action against pathogenic bacteria by designed histidine-rich peptides at acidic pH

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

The role of the abundant phenylalanines in the mode of action of the antimicrobial peptide clavanin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Design and characterization of an acid-activated antimicrobial peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Effect of acidic pH on antibacterial action of peptide isolated from Korean pen shell (Atrina pectinata).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Interactions of an antimicrobial peptide, magainin 2, with outer and inner membranes of Gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Effects of the antimicrobial peptide temporin L on cell morphology, membrane permeability and viability of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Damage of the bacterial cell envelope by antimicrobial peptides gramicidin S and PGLa as revealed by transmission and scanning electron microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Fungaemia caused by Candida glabrata with reduced susceptibility to fluconazole due to altered gene expression: risk factors, antifungal treatment and outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Emerging opportunistic yeast infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Coprisin-induced antifungal effects in Candida albicans correlate with apoptotic mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Candida glabrata is unusual with respect to its resistance to cationic antifungal proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Fungicidal activity of human lactoferrin-derived peptides based on the antimicrobial αβ region

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antifungal susceptibilities of Candida species causing vulvovaginitis and epidemiology of recurrent cases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Human salivary mucin MUC7 12-mer-L and 12-mer-D peptides: antifungal activity in saliva, enhancement of activity with protease inhibitor cocktail or EDTA, and cytotoxicity to human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Human beta-defensin-3: a promising antimicrobial peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Factors affecting antimicrobial activity of MUC7 12-mer, a human salivary mucin-derived peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Evaluation of the inhibitory effects of human serum components on bactericidal activity of human beta defensin 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antifungal Activity of the Noncytotoxic Human Peptide Hepcidin 20 against Fluconazole-Resistant Candida glabrata in Human Vaginal Fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antimicrobial components of vaginal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Proteomic analysis of human cervico-vaginal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Reduction of serum hepcidin by hemodialysis in pediatric and adult patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antibiotic resistance of bacterial biofilms

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

ESCMID guideline for the diagnosis and treatment of biofilm infections 2014.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Evolving concepts in biofilm infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Use of antimicrobial peptides against microbial biofilms: advantages and limits

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Treatment of microbial biofilms in the post-antibiotic era: prophylactic and therapeutic use of antimicrobial peptides and their design by bioinformatics tools

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Cationic amphipathic peptides KT2 and RT2 are taken up into bacterial cells and kill planktonic and biofilm bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Inhibition and destruction of Pseudomonas aeruginosa biofilms by antibiotics and antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Peptide IDR-1018: modulating the immune system and targeting bacterial biofilms to treat antibiotic-resistant bacterial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

BaAMPs: the database of biofilm-active antimicrobial peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Current concepts in biofilm formation of Staphylococcus epidermidis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Inhibitory effect of the human liver-derived antimicrobial peptide hepcidin 20 on biofilms of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains of Staphylococcus epidermidis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Mechanisms of biofilm inhibition and degradation by antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Discovery and development of a synthetic peptide derived from lactoferrin for clinical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Mimicry of bioactive peptides via non-natural, sequence-specific peptidomimetic oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Activity of potent and selective host defense peptide mimetics in mouse models of oral candidiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Trivalent ultrashort lipopeptides are potent pH dependent antifungal agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Synthetic multivalent antifungal peptides effective against fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Nanotools for the delivery of antimicrobial peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Antimicrobial functionalization of silicone surfaces with engineered short peptides having broad spectrum antimicrobial and salt-resistant properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Measurement of skin pH and its significance in cutaneous diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Understanding vaginal microbiome complexity from an ecological perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Progress toward understanding the contribution of alkali generation in dental biofilms to inhibition of dental caries.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Metal-Binding and Nuclease Activity of an Antimicrobial Peptide Analogue of the Salivary Histatin 5†

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Pro-oxidant activity of histatin 5 related Cu(II)-model peptide probed by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

SMAP-29: a potent antibacterial and antifungal peptide from sheep leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Fungicidal activity of five cathelicidin peptides against clinically isolated yeasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/MOLECULES20046319

Human peptidoglycan recognition proteins require zinc to kill both gram-positive and gram-negative bacteria and are synergistic with antibacterial peptides

21 January 2018

1 reference

12 December 2020

Chitosan Nanoparticles for the Linear Release of Model Cationic Peptide

1 reference

12 December 2020

Overcoming the current deadlock in antibiotic research

1 reference

12 December 2020

Effects of antimicrobial peptides on Staphylococcus aureus growth and biofilm formation in vitro following isolation from implant-associated infections

1 reference

12 December 2020

Designing antimicrobial peptides: form follows function.

1 reference

12 December 2020

Fungicidal activity of the human peptide hepcidin 20 alone or in combination with other antifungals against Candida glabrata isolates

1 reference

12 December 2020

Zinc potentiates the antibacterial effects of histidine-rich peptides against Enterococcus faecalis

1 reference

12 December 2020

Biofilms of clinical strains of Staphylococcus that do not contain polysaccharide intercellular adhesin

1 reference

12 December 2020

The Lantibiotic Mersacidin Inhibits Peptidoglycan Biosynthesis at the Level of Transglycosylation

1 reference

12 December 2020

The role of disulfide bonds and N-terminus in the structural properties of hepcidins: insights from molecular dynamics simulations

1 reference

12 December 2020

Antibiotics and bacterial resistance in the 21st century

1 reference

12 December 2020

Amphotericin B- and fluconazole-resistant Candida spp., Aspergillus fumigatus, and other newly emerging pathogenic fungi are susceptible to basic antifungal peptides

1 reference

12 December 2020

Vulvovaginal Candidiasis Caused by Non-albicans Candida Species: New Insights

1 reference

12 December 2020

Synergistic and additive killing by antimicrobial factors found in human airway surface liquid

1 reference

12 December 2020

Preparation, physical–chemical and biological characterization of chitosan nanoparticles loaded with lysozyme

1 reference

12 December 2020

Tuning the membrane selectivity of antimicrobial peptides by using multivalent design

1 reference

12 December 2020

Candida glabrata and FKS mutations: witnessing the emergence of the true multidrug-resistant Candida

1 reference

12 December 2020

1 reference

12 December 2020

10.3390/MOLECULES20046319

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

2277654

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

2277654

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272296&resulttype=core&format=json

13 May 2020

25867823

2 references

Consolidated OpenCitations Corpus – April 2017

2277654