Regulation of Aicda expression and AID activity (Q26853622)

author

Paolo Giovanni Casali

series ordinal

2

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author name string

Hong Zan

series ordinal

1

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language of work or name

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March 2013

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46

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issue

2

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page(s)

83-101

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The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation

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HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation

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MicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocation

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MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase

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Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination

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Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

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The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA

7 April 2017

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miR-181b negatively regulates activation-induced cytidine deaminase in B cells

7 April 2017

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Activation-induced cytidine deaminase expression in CD4 T cells is associated with a unique IL-10-producing subset that increases with age

7 April 2017

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The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

7 April 2017

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The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination

7 April 2017

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Regulation of the germinal center response by microRNA-155

7 April 2017

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The pathogenesis of rheumatoid arthritis

7 April 2017

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Crosstalk in NF-κB signaling pathways

7 April 2017

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Recognition of microorganisms and activation of the immune response

7 April 2017

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Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination

7 April 2017

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BCL6 positively regulates AID and germinal center gene expression via repression of miR-155.

28 September 2017

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A role for the RNA pol II-associated PAF complex in AID-induced immune diversification

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Immunoglobulin class-switch DNA recombination: induction, targeting and beyond

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The cytoplasmic AID complex

28 September 2017

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B cell TLRs and induction of immunoglobulin class-switch DNA recombination

28 September 2017

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Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination

28 September 2017

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28 September 2017

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Immune Cells Have Sex and So Should Journal Articles

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Integration of B cell responses through Toll-like receptors and antigen receptors

28 September 2017

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YY1 Controls Immunoglobulin Class Switch Recombination and Nuclear Activation-Induced Deaminase Levels

28 September 2017

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28 September 2017

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REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase

28 September 2017

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Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A)

28 September 2017

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28 September 2017

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Role of Activation-Induced Cytidine Deaminase in Inflammation-Associated Cancer Development

28 September 2017

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Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

28 September 2017

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Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes

28 September 2017

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Repression of human activation induced cytidine deaminase by miR-93 and miR-155.

28 September 2017

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Hierarchies of NF-κB target-gene regulation

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Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.

28 September 2017

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Activation-induced cytidine deaminase mediates central tolerance in B cells

28 September 2017

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Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans

28 September 2017

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AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4

28 September 2017

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Complex regulation and function of activation-induced cytidine deaminase

28 September 2017

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28 September 2017

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28 September 2017

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Non-canonical NF-κB signaling pathway

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Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination

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Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

28 September 2017

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Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.

28 September 2017

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Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5

28 September 2017

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Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers

28 September 2017

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Estrogen receptors bind to and activate the HOXC4/HoxC4 promoter to potentiate HoxC4-mediated activation-induced cytosine deaminase induction, immunoglobulin class switch DNA recombination, and somatic hypermutation

28 September 2017

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14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.

28 September 2017

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Differential B-lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1.

28 September 2017

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Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis

28 September 2017

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Histone H2A and H2B are monoubiquitinated at AID-targeted loci.

28 September 2017

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Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination

28 September 2017

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Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer

28 September 2017

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GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA.

28 September 2017

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Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity

28 September 2017

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28 September 2017

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B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers

28 September 2017

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AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations

28 September 2017

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A coming-of-age story: activation-induced cytidine deaminase turns 10.

28 September 2017

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The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia

28 September 2017

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Imatinib resistance and progression of CML to blast crisis: somatic hypermutation AIDing the way.

28 September 2017

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Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis

28 September 2017

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Estradiol improves genital herpes vaccine efficacy in mice

28 September 2017

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S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination

28 September 2017

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28 September 2017

Cracking the BAFF code.

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Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation.

28 September 2017

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The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription

28 September 2017

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How location governs toll-like receptor signaling

28 September 2017

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Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes

28 September 2017

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The roles of TLRs, RLRs and NLRs in pathogen recognition

28 September 2017

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Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination

28 September 2017

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Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination.

28 September 2017

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Estrogen directly activates AID transcription and function

28 September 2017

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Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo

28 September 2017

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AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

The X-files in immunity: sex-based differences predispose immune responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Sex differences in autoimmune disease from a pathological perspective

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Hormonal regulation of B-cell function and systemic lupus erythematosus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

The regulation of IgA class switching.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Proteasomal degradation restricts the nuclear lifespan of AID

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Oncogenic events triggered by AID, the adverse effect of antibody diversification

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Role of AID in tumorigenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Signaling pathways downstream of pattern-recognition receptors and their cross talk

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Sex and systemic lupus erythematosus: the role of the sex hormones estrogen and prolactin on the regulation of autoreactive B cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Sex hormones and SLE: influencing the fate of autoreactive B cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Iron chelators: correlation between effects on Plasmodium spp. and immune functions.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Sex hormones and the genesis of autoimmunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

AID mutates a non-immunoglobulin transgene independent of chromosomal position.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

The CD40-CD154 interaction in B cell-T cell liaisons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Antibodies to lipopolysaccharide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

T-independent activation of single B cells: an orderly analysis of overlapping stages in the activation pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Thymus-Independent B-Cell Induction and Paralysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Evidence for a pathogenic determinant in HIV-1 Nef involved in B cell dysfunction in HIV/AIDS.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

AID is required for germinal center-derived lymphomagenesis

31 May 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

AID is required for c-myc/IgH chromosome translocations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Separate domains of AID are required for somatic hypermutation and class-switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

E-proteins directly regulate expression of activation-induced deaminase in mature B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Expression of the AID protein in normal and neoplastic B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Transcription-coupled events associating with immunoglobulin switch region chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Two levels of protection for the B cell genome during somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin κ-chain locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Methylation protects cytidines from AID-mediated deamination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Overexpression of activation-induced cytidine deaminase in B cells is associated with production of highly pathogenic autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Sex differences in autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Constitutive expression of AID leads to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Aberrant expression and mutation-inducing activity of AID in human lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109/08916934.2012.749244

Aberrant somatic hypermutation in transformation of follicular lymphoma and chronic lymphocytic leukemia to diffuse large B-cell lymphoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3762583

Innate immunity: from lymphocyte mitogens to Toll-like receptors and back

28 November 2018

1 reference

12 December 2020

Histone modifications associated with somatic hypermutation

1 reference

12 December 2020

Somatic hypermutation of immunoglobulin kappa transgenes: association of mutability with demethylation

1 reference

12 December 2020

Common variable immunodeficiency and IgG subclass deficiency in central Alabama hemochromatosis probands homozygous for HFE C282Y

1 reference

12 December 2020

The influence of transcriptional orientation on endogenous switch region function

1 reference

12 December 2020

10.3109/08916934.2012.749244

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

23181381

1 reference