Differential pharmacology and clinical utility of emerging combination treatments in the management of COPD--role of umeclidinium/vilanterol (Q26828602)

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English	Differential pharmacology and clinical utility of emerging combination treatments in the management of COPD--role of umeclidinium/vilanterol	scientific article

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scholarly article

1 reference

4 references

17 September 2019

2 October 2019

9 October 2019

7 November 2019

Differential pharmacology and clinical utility of emerging combination treatments in the management of COPD--role of umeclidinium/vilanterol (English)

1 reference

heterocyclic compound

1 reference

17 September 2019

chronic obstructive pulmonary disease

4 references

17 September 2019

2 October 2019

9 October 2019

7 November 2019

mechanism of action

1 reference

2 October 2019

respiratory system

1 reference

9 October 2019

1 reference

7 November 2019

1 reference

7 November 2019

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Alessandro Radaeli

3

2 references

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

Jaymin Bhagwanji Morjaria

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

1 reference

publication date

2014

1 reference

27 June 2014

4 references

17 September 2019

2 October 2019

9 October 2019

7 November 2019

International Journal of Chronic Obstructive Pulmonary Disease

6 references

17 September 2019

2 October 2019

9 October 2019

7 November 2019

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

9

2 references

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

687-695

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

copyright license

Creative Commons Attribution-NonCommercial

4 references

17 September 2019

2 October 2019

9 October 2019

7 November 2019

Diagnosis and Management of Stable Chronic Obstructive Pulmonary Disease: A Clinical Practice Guideline Update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

7 April 2017

Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

7 April 2017

Blurred vision from ipratropium bromide inhalation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

7 April 2017

Urinary Retention Associated with Ipratropium Bromide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

7 April 2017

Safety, tolerability, pharmacodynamics and pharmacokinetics of umeclidinium and vilanterol alone and in combination: a randomized crossover trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

7 April 2017

New developments in the combination treatment of COPD: focus on umeclidinium/vilanterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

The combination of umeclidinium bromide and vilanterol in the management of chronic obstructive pulmonary disease: current evidence and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Tiotropium Respimat inhaler and the risk of death in COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Novel anti-cholinergics in COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Effect of verapamil on systemic exposure and safety of umeclidinium and vilanterol: a randomized and open-label study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

The Tiotropium Safety and Performance in Respimat Trial (TIOSPIR), a large scale, randomized, controlled, parallel-group trial-design and rationale

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

The efficacy and safety of the novel long-acting β2 agonist vilanterol in patients with COPD: a randomized placebo-controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Therapeutic potential for novel ultra long-acting β2-agonists in the management of COPD: biological and pharmacological aspects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Mono- and combination therapy of long-acting bronchodilators and inhaled corticosteroids in advanced COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Tiotropium HandiHaler in the treatment of COPD: a safety review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

A 4-year trial of tiotropium in chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

beta-Agonists and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Ocular hazards of nebulized bronchodilators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 September 2017

Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating metabolic inactivation: an antedrug approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

31 May 2018

Bronchoconstriction induced by ipratropium bromide in asthma: relation to hypotonicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

31 May 2018

Cholinergic bronchomotor tone in COPD. Estimates of its amount in comparison with that in normal subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

31 May 2018

Ventilation-perfusion inequality in asymptomatic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

31 May 2018

Efficacy and safety of umeclidinium plus vilanterol versus tiotropium, vilanterol, or umeclidinium monotherapies over 24 weeks in patients with chronic obstructive pulmonary disease: results from two multicentre, blinded, randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 November 2018

Efficacy and safety of once-daily umeclidinium/vilanterol 62.5/25 mcg in COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 November 2018

Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 November 2018

Initial assessment of single and repeat doses of inhaled umeclidinium in patients with chronic obstructive pulmonary disease: two randomised studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 November 2018

Inhaled Anticholinergic Drug Therapy and the Risk of Acute Urinary Retention in Chronic Obstructive Pulmonary Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 November 2018

Risk for death associated with medications for recently diagnosed chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 November 2018

Quantitation of tremor in response to beta-adrenergic receptor stimulation in primates: relationship with hypokalemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085305

28 November 2018

Bronchodilation of umeclidinium, a new long-acting muscarinic antagonist, in COPD patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25061288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

28-Day safety and tolerability of umeclidinium in combination with vilanterol in COPD: a randomized placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/25061288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vilanterol trifenatate, a novel inhaled long-acting beta2 adrenoceptor agonist, is well tolerated in healthy subjects and demonstrates prolonged bronchodilation in subjects with asthma and COPD

1 reference

https://pubmed.ncbi.nlm.nih.gov/25061288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Umeclidinium in patients with COPD: a randomised, placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25061288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An effect of isoproterenol on ventilation-perfusion in asthmatic versus normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25061288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2147/COPD.S47792

2 references

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

PMC publication ID

2 references

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

2 references

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25061288 AND SRC:MED&resulttype=core&format=json

13 June 2020

ResearchGate publication ID

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