Role of nutrient-sensing signals in the pathogenesis of diabetic nephropathy (Q26828026)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25126552 AND SRC:MED&resulttype=core&format=json

3 June 2020

Hiroshi Maegawa

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25126552 AND SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Daisuke Koya

series ordinal

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25126552 AND SRC:MED&resulttype=core&format=json

3 June 2020

Takashi Uzu

series ordinal

3

2 references

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3 June 2020

language of work or name

1 reference

2014

1 reference

BioMed Research International

14 July 2014

6 references

14 March 2019

24 March 2019

28 September 2019

16 November 2019

31 August 2020

28 January 2021

8 references

14 March 2019

24 March 2019

28 September 2019

16 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25126552 AND SRC:MED&resulttype=core&format=json

3 June 2020

31 August 2020

28 January 2021

2014

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25126552 AND SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

315494

2 references

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Creative Commons Attribution 3.0 Unported

3 June 2020

copyright license

7 references

14 March 2019

24 March 2019

28 September 2019

16 November 2019

29 May 2020

31 August 2020

mTOR: from growth signal integration to cancer, diabetes and ageing

28 January 2021

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Adiponectin regulates albuminuria and podocyte function in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Oxidative stress as a major culprit in kidney disease in diabetes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Adiponectin stimulates phosphorylation of AMP-activated protein kinase alpha in renal glomeruli

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Control of glycogen synthase through ADIPOR1-AMPK pathway in renal distal tubules of normal and diabetic rats

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Autophagy: Renovation of Cells and Tissues

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Autophagy and the Integrated Stress Response

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Metabolite profiles and the risk of developing diabetes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Nutrient sensing, autophagy, and diabetic nephropathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Dietary Restriction Ameliorates Diabetic Nephropathy through Anti-Inflammatory Effects and Regulation of the Autophagy via Restoration of Sirt1 in Diabetic Wistar Fatty (fa/fa) Rats: A Model of Type 2 Diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Franklin H. Epstein Lecture: Sirtuins, aging, and medicine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Autophagy protects the proximal tubule from degeneration and acute ischemic injury.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

The Tuberin/mTOR Pathway Promotes Apoptosis of Tubular Epithelial Cells in Diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Cellular metabolic stress: considering how cells respond to nutrient excess.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Tetrahydroxystilbene glucoside ameliorates diabetic nephropathy in rats: Involvement of SIRT1 and TGF-β1 pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Sirolimus for calcineurin inhibitors in organ transplantation: contra

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Mitochondria in response to nutrients and nutrient-sensitive pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Sirtuins and their relevance to the kidney.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Sirt1 activation protects the mouse renal medulla from oxidative injury

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Role of the energy sensor AMP-activated protein kinase in renal physiology and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Kidney-specific overexpression of Sirt1 protects against acute kidney injury by retaining peroxisome function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

SRT1720 induces mitochondrial biogenesis and rescues mitochondrial function after oxidant injury in renal proximal tubule cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Endoplasmic reticulum stress in proteinuric kidney disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

AMPK in Health and Disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Proteinuria and hyperglycemia induce endoplasmic reticulum stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

PpAtg30 tags peroxisomes for turnover by selective autophagy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Change in histone H3 phosphorylation, MAP kinase p38, SIR 2 and p53 expression by resveratrol in preventing streptozotocin induced type I diabetic nephropathy

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122096

Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice

31 May 2018

1 reference

The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential.

21 January 2018

1 reference

Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy

21 January 2018

1 reference

Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions

21 January 2018

1 reference

Autophagy guards against cisplatin-induced acute kidney injury

21 January 2018

1 reference

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

21 January 2018

1 reference

12 December 2020

Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

1 reference

12 December 2020

Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation

1 reference

12 December 2020

A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy

1 reference

12 December 2020

Effect of N-acetylcysteine on plasma adiponectin and renal adiponectin receptors in streptozotocin-induced diabetic rats

1 reference

12 December 2020

Rapamycin prevents early steps of the development of diabetic nephropathy in rats

1 reference

12 December 2020

Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/315494

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25126552 AND SRC:MED&resulttype=core&format=json

release_ozfmyaz2bbf6lcu43qagupcypq

3 June 2020

Fatcat ID

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25126552 AND SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

25126552

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25126552 AND SRC:MED&resulttype=core&format=json