TDP-43: a new player on the AD field? (Q26823723)

Crossref

Benjamin Wolozin

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

September 2012

1 reference

published in

Experimental Neurology

1 reference

volume

237

1 reference

issue

1

1 reference

page(s)

90-5

1 reference

Alzheimer Disease in the US Population

cites work

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28 September 2017

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National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

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Local RNA Translation at the Synapse and in Disease: Figure 1

28 September 2017

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Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

28 September 2017

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Introducing Human APOE into Aβ Transgenic Mouse Models

28 September 2017

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Progranulin and TDP-43: mechanistic links and future directions

28 September 2017

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The frontotemporal syndromes of ALS. Clinicopathological correlates.

28 September 2017

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28 September 2017

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Structure, function, and mechanism of progranulin; the brain and beyond

28 September 2017

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Hippocampal sclerosis in advanced age: clinical and pathological features.

28 September 2017

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BACE Inhibitors as Potential Drugs for the Treatment of Alzheimers Disease: Focus on Bioactivity

28 September 2017

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TDP-43 in aging and Alzheimer's disease - a review

28 September 2017

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Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

28 September 2017

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Neuroprotective strategies involving ROS in Alzheimer disease

28 September 2017

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Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways.

28 September 2017

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Possible roles of amyloid intracellular domain of amyloid precursor protein

28 September 2017

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Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review

28 September 2017

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Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

28 September 2017

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beta-Amyloid precursor protein metabolism: focus on the functions and degradation of its intracellular domain

28 September 2017

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The role of microglia in amyloid clearance from the AD brain

28 September 2017

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Endocytic pathways mediating oligomeric Abeta42 neurotoxicity.

28 September 2017

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Mitochondrial dysfunction is a converging point of multiple pathological pathways in amyotrophic lateral sclerosis

28 September 2017

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Mitochondrial DNA mutation-elicited oxidative stress, oxidative damage, and altered gene expression in cultured cells of patients with MERRF syndrome

28 September 2017

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Import, maturation, and function of SOD1 and its copper chaperone CCS in the mitochondrial intermembrane space

28 September 2017

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Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease

28 September 2017

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Accumulation of intraneuronal Abeta correlates with ApoE4 genotype

28 September 2017

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Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis

28 September 2017

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TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

28 September 2017

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TDP-43 is a developmentally regulated protein essential for early embryonic development

28 September 2017

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28 September 2017

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Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

28 September 2017

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28 September 2017

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28 September 2017

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Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases

28 September 2017

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TDP-43 proteinopathies: neurodegenerative protein misfolding diseases without amyloidosis

28 September 2017

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Autophagy, amyloidogenesis and Alzheimer disease

28 September 2017

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28 September 2017

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28 September 2017

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Mitochondrial oxidative stress: implications for cell death

28 September 2017

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Lysosomal system pathways: genes to neurodegeneration in Alzheimer's disease

28 September 2017

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Abeta42 neurotoxicity in primary co-cultures: effect of apoE isoform and Abeta conformation

28 September 2017

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28 September 2017

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A dynamic relationship between intracellular and extracellular pools of Abeta

28 September 2017

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Inhibition of cyclooxygenase as potential novel therapeutic strategy in N141I presenilin-2 familial Alzheimer's disease

28 September 2017

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Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

28 September 2017

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Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

28 September 2017

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Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice

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Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

28 September 2017

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28 September 2017

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Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology

28 September 2017

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The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

28 September 2017

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Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

28 September 2017

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Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

28 September 2017

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Oligomerizaiton and fibril asssembly of the amyloid-beta protein.

28 September 2017

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Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization

28 September 2017

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Amyloid-β42 alters apolipoprotein E solubility in brains of mice with five familial AD mutations

28 September 2017

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Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

31 May 2018

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Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation.

31 May 2018

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Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching

31 May 2018

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Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

31 May 2018

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Increased Neuronal Endocytosis and Protease Delivery to Early Endosomes in Sporadic Alzheimer’s Disease: Neuropathologic Evidence for a Mechanism of Increased β-Amyloidogenesis

31 May 2018

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Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments

31 May 2018

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A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

28 November 2018

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Genetic association analysis between TDP-43 polymorphisms and Alzheimer's disease in a Japanese population.

28 November 2018

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Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior

28 November 2018

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Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.

28 November 2018

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Differential effects of oligomeric and fibrillar amyloid-beta 1-42 on astrocyte-mediated inflammation.

28 November 2018

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Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmented cultures

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Reconstitution of gamma-secretase activity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Apolipoprotein E enhances uptake of soluble but not aggregated amyloid-beta protein into synaptic terminals

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

CNS synaptogenesis promoted by glia-derived cholesterol

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Protofibrils, the unifying toxic molecule of neurodegenerative disorders?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

An honorable compromise regarding amyloid in Alzheimer disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3910368

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22691390

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EXPNEUROL.2012.05.018

0 references

Fatcat ID

release_7mmbdqfqqjfwhd5irp5bwwoi2e

0 references

1 reference

PubMed publication ID

22691390

1 reference