Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy (Q26797284)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

1 June 2020

Saverio Marchi

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

1 June 2020

2

Sonia Missiroli

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

1 June 2020

4

Carlotta Giorgi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

2015

0 references

published in

Frontiers in Oncology

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

1 June 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance

1 June 2020

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Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology

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Autophagosomes form at ER-mitochondria contact sites

7 April 2017

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Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

7 April 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy

7 April 2017

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Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

7 April 2017

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The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

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Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy

7 April 2017

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A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2

7 April 2017

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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

7 April 2017

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Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

7 April 2017

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Ambra1 regulates autophagy and development of the nervous system

7 April 2017

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The mechanisms of PML-nuclear body formation

7 April 2017

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7 April 2017

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Autophagy in malignant transformation and cancer progression

7 April 2017

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Autophagy modulation as a potential therapeutic target for diverse diseases

7 April 2017

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Autophagy in kidney health and disease

7 April 2017

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Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy

7 April 2017

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

7 April 2017

1 reference

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PML regulates apoptosis at endoplasmic reticulum by modulating calcium release

7 April 2017

1 reference

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Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis

7 April 2017

1 reference

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An expanding role for mTOR in cancer

7 April 2017

1 reference

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3D tomography reveals connections between the phagophore and endoplasmic reticulum

7 April 2017

1 reference

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Autophagy: Renovation of Cells and Tissues

7 April 2017

1 reference

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The Role of Atg Proteins in Autophagosome Formation

7 April 2017

1 reference

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Autophagy: process and function

7 April 2017

1 reference

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Mitochondrial membrane permeabilization in cell death

7 April 2017

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Autophagy in human health and disease

7 April 2017

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Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

7 April 2017

1 reference

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Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

7 April 2017

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Mitochondria supply membranes for autophagosome biogenesis during starvation

7 April 2017

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Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

7 April 2017

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Autophagy in health and disease: a double-edged sword

7 April 2017

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Mitochondrial control of cell death

7 April 2017

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Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2 responses

7 April 2017

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p53 at the endoplasmic reticulum regulates apoptosis in a Ca2 -dependent manner

7 April 2017

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Mitochondria-associated membranes: composition, molecular mechanisms, and physiopathological implications

28 September 2017

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Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling

28 September 2017

1 reference

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Current treatment strategies for inhibiting mTOR in cancer

28 September 2017

1 reference

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Mitophagy and mitochondrial balance

28 September 2017

1 reference

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Mitochondria: from cell death executioners to regulators of cell differentiation

28 September 2017

1 reference

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Tumor vessel normalization by chloroquine independent of autophagy.

28 September 2017

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Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1α signaling

28 September 2017

1 reference

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Combined MTOR and autophagy inhibition: phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma

28 September 2017

1 reference

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Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer

28 September 2017

1 reference

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The role of inflammation in sarcoma

28 September 2017

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The role of inflammation in gastric cancer

28 September 2017

1 reference

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The role of inflammation in lung cancer.

28 September 2017

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New functions of mitochondria associated membranes in cellular signaling.

28 September 2017

1 reference

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Drugging the p53 pathway: understanding the route to clinical efficacy

28 September 2017

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The machinery of macroautophagy

28 September 2017

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MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond

28 September 2017

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The endoplasmic reticulum-mitochondria connection: one touch, multiple functions.

28 September 2017

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The autophagosome: origins unknown, biogenesis complex

28 September 2017

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Perturbed mitochondrial Ca2 signals as causes or consequences of mitophagy induction

28 September 2017

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New perspective for an old antidiabetic drug: metformin as anticancer agent.

28 September 2017

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Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

28 September 2017

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BH3 mimetics: status of the field and new developments

28 September 2017

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Therapeutic targeting of autophagy in disease: biology and pharmacology

28 September 2017

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Nilotinib induces autophagy in hepatocellular carcinoma through AMPK activation

28 September 2017

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Beclin-1: autophagic regulator and therapeutic target in cancer

28 September 2017

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PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations

28 September 2017

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Selective modulation of subtype III IP₃R by Akt regulates ER Ca²⁺ release and apoptosis

28 September 2017

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Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer

28 September 2017

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Programmed cell death in animal development and disease

28 September 2017

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Cell death by autophagy: facts and apparent artefacts

28 September 2017

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Mitochondria associated membranes (MAMs) as critical hubs for apoptosis

28 September 2017

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Calcium signaling around Mitochondria Associated Membranes (MAMs).

28 September 2017

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The role of autophagy in cancer: therapeutic implications

28 September 2017

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Calorie Restriction: Is AMPK a Key Sensor and Effector?

28 September 2017

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Alternative cell death mechanisms in development and beyond

28 September 2017

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The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

28 September 2017

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Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2 transfer to mitochondria.

28 September 2017

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Inhibition of Akt signaling in hepatoma cells induces apoptotic cell death independent of Akt activation status.

28 September 2017

1 reference

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Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface

28 September 2017

1 reference

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A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease

28 September 2017

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Direct control of mitochondrial function by mTOR.

28 September 2017

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PGC-1alpha activation as a therapeutic approach in mitochondrial disease

28 September 2017

1 reference

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Anti- and pro-tumor functions of autophagy

28 September 2017

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Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart

28 September 2017

1 reference

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Bcl-2 family members: dual regulators of apoptosis and autophagy

28 September 2017

1 reference

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Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

28 September 2017

1 reference

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Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival.

28 September 2017

1 reference

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Structural and functional features and significance of the physical linkage between ER and mitochondria.

28 September 2017

1 reference

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Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

28 September 2017

1 reference

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Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy

28 September 2017

1 reference

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Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors

28 September 2017

1 reference

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Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death.

28 September 2017

1 reference

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Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway

28 September 2017

1 reference

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How death shapes life during development

28 September 2017

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FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

28 September 2017

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28 September 2017

Autophagy and cell death

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Identification of PTEN at the ER and MAMs and its regulation of Ca(2 ) signaling and apoptosis in a protein phosphatase-dependent manner

31 May 2018

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H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling.

31 May 2018

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Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

31 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515599

AMPK and autophagy get connected.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515599

Life and death partners: apoptosis, autophagy and the cross-talk between them

31 May 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

Do inducers of apoptosis trigger caspase-independent cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

AMPK and autophagy get connected.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

Akt kinase reducing endoplasmic reticulum Ca2 release protects cells from Ca2 -dependent apoptotic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

PP2A regulates autophagy in two alternative ways in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

PP2A blockade inhibits autophagy and causes intraneuronal accumulation of ubiquitinated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

Metformin prevents glucose-induced protein kinase C-beta2 activation in human umbilical vein endothelial cells through an antioxidant mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FONC.2015.00173

Lipophagy: selective catabolism designed for lipids

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26284195

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26284195

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FONC.2015.00173

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

26284195

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284195 AND SRC:MED&resulttype=core&format=json