Autophagy in airway diseases: a new frontier in human asthma? (Q26786115)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26335713 AND SRC:MED&resulttype=core&format=json

1 June 2020

author name string

A A Zeki

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26335713 AND SRC:MED&resulttype=core&format=json

1 June 2020

B Yeganeh

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26335713 AND SRC:MED&resulttype=core&format=json

1 June 2020

N J Kenyon

3

1 reference

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1 June 2020

M Post

4

1 reference

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1 June 2020

language of work or name

English

0 references

publication date

January 2016

0 references

published in

Allergy

1 reference

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1 June 2020

volume

71

1 reference

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1 June 2020

issue

1

1 reference

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1 June 2020

page(s)

5-14

1 reference

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Guidelines for the use and interpretation of assays for monitoring autophagy

1 June 2020

cites work

1 reference

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Autophagy: molecular machinery for self-eating

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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

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The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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Discovery of (2S)-8-[(3R)-3-methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido[1,2-a]pyrimidin-6-one: a novel potent and selective inhibitor of Vps34 for the treatment of solid tumors

7 April 2017

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A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

7 April 2017

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Autophagy in the Pathogenesis of Disease

7 April 2017

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Unconventional secretion of Acb1 is mediated by autophagosomes.

7 April 2017

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In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

7 April 2017

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A ubiquitin-like system mediates protein lipidation

7 April 2017

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Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting

7 April 2017

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Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

7 April 2017

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Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

7 April 2017

1 reference

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A protein conjugation system essential for autophagy

7 April 2017

1 reference

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Sphingolipids as cell fate regulators in lung development and disease

7 April 2017

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Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

7 April 2017

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Regulation mechanisms and signaling pathways of autophagy

7 April 2017

1 reference

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Autophagosome formation: core machinery and adaptations

7 April 2017

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The role of autophagy during the early neonatal starvation period

7 April 2017

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Development by self-digestion: molecular mechanisms and biological functions of autophagy

7 April 2017

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7 April 2017

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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

7 April 2017

1 reference

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Targeting PI3K signalling in cancer: opportunities, challenges and limitations

7 April 2017

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Dynamics and diversity in autophagy mechanisms: lessons from yeast

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts

28 September 2017

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Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1.

28 September 2017

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Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

28 September 2017

1 reference

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Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

28 September 2017

1 reference

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Lessons learned from mice and man: mimicking human allergy through mouse models

28 September 2017

1 reference

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mTOR and autophagy in regulation of acute lung injury: a review and perspective

28 September 2017

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Instructive roles of extracellular matrix on autophagy.

28 September 2017

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Autophagy and heart disease: implications for cardiac ischemia-reperfusion damage.

28 September 2017

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Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics.

28 September 2017

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Autophagy and apoptosis dysfunction in neurodegenerative disorders

28 September 2017

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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics.

28 September 2017

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28 September 2017

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Asthma and influenza virus infection:focusing on cell death and stress pathways in influenza virus replication.

28 September 2017

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Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells

28 September 2017

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Clinical development of phosphatidylinositol 3-kinase inhibitors for cancer treatment

28 September 2017

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Autophagy and role in asthma

28 September 2017

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Novel non-canonical TGF-β signaling networks: emerging roles in airway smooth muscle phenotype and function.

28 September 2017

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Into the matrix: targeting fibroblasts in pulmonary fibrosis

28 September 2017

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Chronic inflammation and lung fibrosis: pleotropic syndromes but limited distinct phenotypes

28 September 2017

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Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation

28 September 2017

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LC3 as a potential therapeutic target in hypoxia-induced pulmonary hypertension

28 September 2017

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Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma

28 September 2017

1 reference

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Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

28 September 2017

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Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion

28 September 2017

1 reference

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Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death

28 September 2017

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Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development

28 September 2017

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Genetic and histologic evidence for autophagy in asthma pathogenesis

28 September 2017

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Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts

28 September 2017

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Scraping fibrosis: expressway to the core of fibrosis

28 September 2017

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Small-molecule inhibitors of the PI3K signaling network

28 September 2017

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High-throughput fluorescence assay for small-molecule inhibitors of autophagins/Atg4.

28 September 2017

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Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension

28 September 2017

1 reference

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Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

28 September 2017

1 reference

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The mevalonate cascade as a target to suppress extracellular matrix synthesis by human airway smooth muscle

28 September 2017

1 reference

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Development of phosphoinositide-3 kinase pathway inhibitors for advanced cancer

28 September 2017

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mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex

28 September 2017

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Role of autophagy and proteasome degradation pathways in apoptosis of PC12 cells overexpressing human alpha-synuclein

28 September 2017

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Anti- and pro-tumor functions of autophagy

28 September 2017

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Autophagy and human disease

28 September 2017

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Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons.

28 September 2017

1 reference

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Airway remodeling and airway smooth muscle in asthma

28 September 2017

1 reference

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Transforming growth factor-beta1 and disorders of the lung

28 September 2017

1 reference

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Autophagy: a regulated bulk degradation process inside cells

28 September 2017

1 reference

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Approaching the molecular mechanism of autophagy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715640

Biopsy markers of airway inflammation and remodelling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715640

Morphologic changes in pulmonary oxygen toxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715640

Peroxisome degradation in Saccharomyces cerevisiae is dependent on machinery of macroautophagy and the Cvt pathway.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4715640

Airway mesenchymal cell death by mevalonate cascade inhibition: integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins

31 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111/ALL.12761

Targeting autophagy enhances BO-1051-induced apoptosis in human malignant glioma cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111/ALL.12761

Insufficient autophagy in idiopathic pulmonary fibrosis.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111/ALL.12761

Phosphoinositide 3-kinase pathway inhibitors: pharmacology, metabolism & drug development

21 January 2018

1 reference

12 December 2020

Airway remodeling in asthma

1 reference

12 December 2020

More muscle in asthma, but where did it come from?

1 reference

12 December 2020

l-Carnitine enhances extracellular matrix synthesis in human primary chondrocytes

1 reference

12 December 2020

[Anti-nerve growth factor antibody reduces airway hyperresponsiveness in a mouse model of asthma by down-regulating the level of autophagy in lungs]

1 reference

12 December 2020

Identifiers

DOI

10.1111/ALL.12761

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26335713 AND SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26335713 AND SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

26335713

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26335713 AND SRC:MED&resulttype=core&format=json