Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilarities (Q26782080)

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English	Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilarities	scientific article

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scholarly article

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5 references

8 September 2019

20 November 2019

21 December 2019

23 July 2020

10 September 2020

Eyeing the Cyr61/CTGF/NOV (CCN) group of genes in development and diseases: highlights of their structural likenesses and functional dissimilarities (English)

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regulation of gene expression

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8 September 2019

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20 November 2019

fibrous protein

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21 December 2019

genetic predisposition to disease

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23 July 2020

Elspeth A Bruford

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Elspeth A Bruford

2

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author name string

Izabela Krupska

1

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Brahim Chaqour

3

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language of work or name

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publication date

2015

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23 September 2015

5 references

8 September 2019

20 November 2019

21 December 2019

23 July 2020

10 September 2020

5 references

8 September 2019

20 November 2019

21 December 2019

23 July 2020

9

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1

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24

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copyright license

Creative Commons Attribution 4.0 International

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Europe PubMed Central

8 September 2019

Europe PubMed Central

20 November 2019

Europe PubMed Central

21 December 2019

Europe PubMed Central

23 July 2020

Europe PubMed Central

10 September 2020

copyright status

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CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis

1 reference

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7 April 2017

The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy

1 reference

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7 April 2017

CCN5: biology and pathophysiology

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7 April 2017

WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

The CCN family of proteins: structure-function relationships

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

Functions and mechanisms of action of CCN matricellular proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

The matricellular protein CCN1 is essential for cardiac development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

CCN5 modulates the antiproliferative effect of heparin and regulates cell motility in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

CYR61 (CCN1) is essential for placental development and vascular integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p

1 reference

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7 April 2017

Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily

1 reference

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7 April 2017

Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165

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7 April 2017

Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions

1 reference

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7 April 2017

The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor is a receptor for connective tissue growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

Physical mapping of human loci homologous to the chicken nov proto-oncogene

1 reference

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7 April 2017

Antiproliferative activity of CCN3: involvement of the C-terminal module and post-translational regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

CCN3/NOV inhibits BMP-2-induced osteoblast differentiation by interacting with BMP and Notch signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

All in the CCN family: essential matricellular signaling modulators emerge from the bunker

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

The Twisted gastrulation family of proteins, together with the IGFBP and CCN families, comprise the TIC superfamily of cysteine rich secreted factors

1 reference

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7 April 2017

5' flanking sequence of the human immediate early responsive gene ccn1 (cyr61) and mapping of polymorphic CA repeat sequence motifs in the human ccn1 (cyr61) locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

CCN3 protein participates in bone regeneration as an inhibitory factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

Pulmonary hypoplasia in the connective tissue growth factor (Ctgf) null mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

The angiogenic factor cysteine-rich 61 (CYR61, CCN1) supports vascular smooth muscle cell adhesion and stimulates chemotaxis through integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

7 April 2017

The matricellular protein CCN1 controls retinal angiogenesis by targeting VEGF, Src homology 2 domain phosphatase-1 and Notch signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

The matricellular protein CCN1 promotes mucosal healing in murine colitis through IL-6.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

"Knock once for yes, twice for no"

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28 September 2017

Pulmonary hypertension in giant omphalocele infants

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28 September 2017

Silencing of WISP3 suppresses gastric cancer cell proliferation and metastasis and inhibits Wnt/β-catenin signaling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Revisiting the matricellular concept

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28 September 2017

Association between gene polymorphisms of connective tissue growth factor and the progression of chronic liver disease associated with hepatitis C.

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28 September 2017

Conditional knockout of CTGF affects corneal wound healing

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28 September 2017

Loss of WISP2/CCN5 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype

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28 September 2017

WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone

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28 September 2017

Degradome products of the matricellular protein CCN1 as modulators of pathological angiogenesis in the retina.

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28 September 2017

Cysteine-rich protein 61 (CCN1) and connective tissue growth factor (CCN2) at the crosshairs of ocular neovascular and fibrovascular disease therapy

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28 September 2017

CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress

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28 September 2017

Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro.

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28 September 2017

CCN6: a novel method of aTAKing cancer

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28 September 2017

Tuberous sclerosis protein 2 (TSC2) modulates CCN4 cytoprotection during apoptotic amyloid toxicity in microglia

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28 September 2017

CCN6 knockdown disrupts acinar organization of breast cells in three-dimensional cultures through up-regulation of type III TGF-β receptor

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28 September 2017

WISP1 neuroprotection requires FoxO3a post-translational modulation with autoregulatory control of SIRT1

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28 September 2017

Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

CCN5 Expression in mammals. III. Early embryonic mouse development

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28 September 2017

CCN1 and CCN2: blood brothers in angiogenic action.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

CCN6 modulates BMP signaling via the Smad-independent TAK1/p38 pathway, acting to suppress metastasis of breast cancer

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28 September 2017

CCN2/CTGF regulates neovessel formation via targeting structurally conserved cystine knot motifs in multiple angiogenic regulators.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

WISP1 (CCN4) Autoregulates its Expression and Nuclear Trafficking of β-Catenin during Oxidant Stress with Limited Effects upon Neuronal Autophagy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Dual regulation of metalloproteinase expression in chondrocytes by Wnt-1-inducible signaling pathway protein 3/CCN6.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

WNT1 inducible signaling pathway protein 1 (WISP1): A novel mediator linking development and disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

A Mouse Strain Where Basal Connective Tissue Growth Factor Gene Expression Can Be Switched from Low to High

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Temporal and spatial expression of CCN genes in zebrafish

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

The opposing effects of CCN2 and CCN5 on the development of cardiac hypertrophy and fibrosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Regulation of the matricellular proteins CYR61 (CCN1) and NOV (CCN3) by hypoxia-inducible factor-1{alpha} and transforming-growth factor-{beta}3 in the human trophoblast

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Variants of CTGF are associated with hepatic fibrosis in Chinese, Sudanese, and Brazilians infected with schistosomes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Actions of IGF binding proteins and related proteins in adipose tissue

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Proteins on the catwalk: modelling the structural domains of the CCN family of proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Role of CCN, a vertebrate specific gene family, in development

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Mechanical strain activates a program of genes functionally involved in paracrine signaling of angiogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

CCN5/WISP-2 expression in breast adenocarcinoma is associated with less frequent progression of the disease and suppresses the invasive phenotypes of tumor cells

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28 September 2017

CCN5 expression in mammals : I. Embryonic and fetal tissues of mouse and human

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28 September 2017

Exercise-induced expression of angiogenic growth factors in skeletal muscle and in capillaries of healthy and diabetic mice

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28 September 2017

TGF-beta1 and WISP-1/CCN-4 can regulate each other's activity to cooperatively control osteoblast function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

A polymorphism in the CTGF promoter region associated with systemic sclerosis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Expression and physiological role of CCN4/Wnt-induced secreted protein 1 mRNA splicing variants in chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Forkhead transcription factor FOXO3a is a negative regulator of angiogenic immediate early gene CYR61, leading to inhibition of vascular smooth muscle cell proliferation and neointimal hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Functional properties and intracellular signaling of CCN1/Cyr61.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

CCN family proteins and angiogenesis: from embryo to adulthood

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter region

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Mechanical regulation of the Cyr61/CCN1 and CTGF/CCN2 proteins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Cyr61 mediates the expression of VEGF, alphav-integrin, and alpha-actin genes through cytoskeletally based mechanotransduction mechanisms in bladder smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Regulation of proangiogenic factor CCN1 in cardiac muscle: impact of ischemia, pressure overload, and neurohumoral activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

The growth arrest-specific gene CCN5 is deficient in human leiomyomas and inhibits the proliferation and motility of cultured human uterine smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Role of the extracellular matrix in morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Matricellular proteins: extracellular modulators of cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

A novel variant of WISP1 lacking a Von Willebrand type C module overexpressed in scirrhous gastric carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

COP-1, a member of the CCN family, is a heparin-induced growth arrest specific gene in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

The expression of ccn3 (nov) RNA and protein in the rat central nervous system is developmentally regulated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Promoter function of the angiogenic inducer Cyr61gene in transgenic mice: tissue specificity, inducibility during wound healing, and role of the serum response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Gene expression in rat dermal papilla cells: analysis of 2529 ESTs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Chromosomal mapping and expression of the human cyr61 gene in tumour cells from the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Adhesion of Human Umbilical Vein Endothelial Cells to the Immediate-Early Gene Product Cyr61 Is Mediated through Integrin αvβ3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Identification of a phorbol ester-repressible v-src-inducible gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 September 2017

Identification of a mutation in the WISP3 gene in three unrelated families with progressive pseudorheumatoid dysplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

31 May 2018

CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

31 May 2018

Characterization of 16- to 20-kilodalton (kDa) connective tissue growth factors (CTGFs) and demonstration of proteolytic activity for 38-kDa CTGF in pig uterine luminal flushings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

31 May 2018

Domain organizations of modular extracellular matrix proteins and their evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

31 May 2018

CCN1 mutation is associated with atrial septal defect.

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Expression profiles of human CCN genes in patients with osteoarthritis or rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Identification of cellular MMP substrates using quantitative proteomics: isotope-coded affinity tags (ICAT) and isobaric tags for relative and absolute quantification (iTRAQ).

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Differential gene expression in the proximal neck of human abdominal aortic aneurysm

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Cloning the full-length cDNA for rat connective tissue growth factor: implications for skeletal development

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Tgf-beta auto-induction and connective tissue growth factor expression in human renal tubule epithelial cells requires N-ras.

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

NOV/CCN3 induces adhesion of muscle skeletal cells and cooperates with FGF2 and IGF-1 to promote proliferation and survival.

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Promotion of dentin regeneration via CCN3 modulation on Notch and BMP signaling pathways

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis.

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

CCN5 Expression in mammals. II. Adult rodent tissues

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

ZFP36: a Promising Candidate Gene for Obesity-Related Metabolic Complications Identified by Converging Genomics

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

CYR61 polymorphisms are associated with plasma HDL-cholesterol levels in obese individuals

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Myofibroblasts in proliferative diabetic retinopathy can originate from infiltrating fibrocytes and through endothelial-to-mesenchymal transition (EndoMT)

1 reference

https://api.crossref.org/works/10.1186/S40246-015-0046-Y

21 January 2018

Comparative genomics on Norrie disease gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 November 2018

Stimulation of MCF-7 tumor progression in athymic nude mice by 17beta-estradiol induces WISP-2/CCN5 expression in xenografts: a novel signaling molecule in hormonal carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 November 2018

Molecular response of the bladder to obstruction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 November 2018

Matricellular proteins as modulators of wound healing and the foreign body response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4579636

28 November 2018

Genetic analysis of human predisposition to hepatosplenic disease caused by schistosomes reveals the crucial role of connective tissue growth factor in rapid progression to severe hepatic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26395334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine-rich 61 (CYR61) is up-regulated in proliferative diabetic retinopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/26395334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCN proteins are distinct from and should not be considered members of the insulin-like growth factor-binding protein superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/26395334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S40246-015-0046-Y

0 references

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0 references

release_wkqnawbsyja5zdf77hh77gvrsy

0 references

PMC publication ID

0 references

PubMed publication ID

0 references

ResearchGate publication ID

0 references

Sitelinks

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