The Role of Oxidative Stress-Induced Epigenetic Alterations in Amyloid-β Production in Alzheimer's Disease (Q26778776)

PubMed

regulation of gene expression

20 August 2019

1 reference

8 September 2019

1 reference

20 November 2019

1 reference

15 December 2019

0 references

1 reference

25 September 2020

Li Zuo

1

0 references

Benjamin T Hemmelgarn

series ordinal

2

0 references

Chia-Chen Chuang

series ordinal

3

0 references

Thomas M Best

series ordinal

4

0 references

language of work or name

English

0 references

publication date

12 October 2015

6 references

25 April 2019

20 August 2019

8 September 2019

20 November 2019

15 December 2019

25 September 2020

Oxidative Medicine and Cellular Longevity

7 references

25 April 2019

20 August 2019

8 September 2019

20 November 2019

15 December 2019

25 September 2020

2015

0 references

page(s)

604658

0 references

copyright license

Creative Commons Attribution 3.0 Unported

7 references

25 April 2019

20 August 2019

8 September 2019

20 November 2019

15 December 2019

20 September 2020

on focus list of Wikimedia project

25 September 2020

copyright status

copyrighted

0 references

ScienceSource

0 references

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Oxidative stress in neurodegeneration: cause or consequence?

7 April 2017

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Diversity of structures and properties among catalases

7 April 2017

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A specific amyloid-beta protein assembly in the brain impairs memory

7 April 2017

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Signal transduction by reactive oxygen species

7 April 2017

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Intracellular amyloid-beta in Alzheimer's disease

7 April 2017

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Oxidative stress and neurodegeneration: where are we now?

7 April 2017

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Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory

7 April 2017

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Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

7 April 2017

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Methylation-induced repression--belts, braces, and chromatin

7 April 2017

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Amyloid deposition as the central event in the aetiology of Alzheimer's disease

7 April 2017

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Histone acetyltransferase p300 mediates histone acetylation of PS1 and BACE1 in a cellular model of Alzheimer's disease

7 April 2017

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Resveratrol and Alzheimer's disease: message in a bottle on red wine and cognition

28 September 2017

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28 September 2017

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β-amyloid fibrils in Alzheimer disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species.

28 September 2017

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The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease

28 September 2017

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28 September 2017

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Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits

28 September 2017

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28 September 2017

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28 September 2017

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Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients.

28 September 2017

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28 September 2017

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28 September 2017

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Oxidative stress induces DNA demethylation and histone acetylation in SH-SY5Y cells: potential epigenetic mechanisms in gene transcription in Aβ production

28 September 2017

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Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Mitochondria, oxidative stress and neurodegeneration.

28 September 2017

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Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint.

28 September 2017

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28 September 2017

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Rutin inhibits β-amyloid aggregation and cytotoxicity, attenuates oxidative stress, and decreases the production of nitric oxide and proinflammatory cytokines

28 September 2017

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A multifunctional peptide rescues memory deficits in Alzheimer's disease transgenic mice by inhibiting Aβ42-induced cytotoxicity and increasing microglial phagocytosis

28 September 2017

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28 September 2017

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Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway

28 September 2017

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Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation

28 September 2017

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SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease

28 September 2017

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28 September 2017

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Quercetin and rutin exhibit antiamyloidogenic and fibril-disaggregating effects in vitro and potent antioxidant activity in APPswe cells.

28 September 2017

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Amyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line

28 September 2017

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SuHeXiang Wan essential oil alleviates amyloid beta induced memory impairment through inhibition of tau protein phosphorylation in mice

28 September 2017

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28 September 2017

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Epigenetic mechanisms of amyloid-β production in anisomycin-treated SH-SY5Y cells

28 September 2017

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Distinct effects of Zn2 , Cu2 , Fe3 , and Al3 on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation

28 September 2017

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Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

28 September 2017

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Reactive oxygen species: stuck in the middle of neurodegeneration

28 September 2017

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Oxidative stress in Alzheimer disease: a possibility for prevention

28 September 2017

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Oxidative stress in the progression of Alzheimer disease in the frontal cortex

28 September 2017

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Pathological roles of MAPK signaling pathways in human diseases

28 September 2017

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Role of reactive oxygen species-elicited apoptosis in the pathophysiology of mitochondrial and neurodegenerative diseases associated with mitochondrial DNA mutations.

28 September 2017

1 reference

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S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters

28 September 2017

1 reference

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PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease

28 September 2017

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Epigenetic dysregulation in cognitive disorders.

28 September 2017

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Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase

28 September 2017

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RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model.

28 September 2017

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Epigenetics, oxidative stress, and Alzheimer disease

28 September 2017

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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

28 September 2017

1 reference

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Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

28 September 2017

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Age-specific epigenetic drift in late-onset Alzheimer's disease

28 September 2017

1 reference

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Curcumin: from ancient medicine to current clinical trials.

28 September 2017

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Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

28 September 2017

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Mitochondrial dysfunction and age.

28 September 2017

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Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis

28 September 2017

1 reference

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Reactive oxygen species and superoxide dismutases: role in joint diseases

28 September 2017

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Inverse correlation between amyloid precursor protein and synaptic plasticity in transgenic mice

28 September 2017

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Autophagy and neurodegeneration: when the cleaning crew goes on strike

28 September 2017

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Oxidative stress mediates tau-induced neurodegeneration in Drosophila

28 September 2017

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Gene silencing through methylation: an epigenetic intervention on Alzheimer disease

28 September 2017

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Resveratrol--a boon for treating Alzheimer's disease?

28 September 2017

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Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview.

28 September 2017

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Amyloid-beta causes apoptosis of neuronal cells via caspase cascade, which can be prevented by amyloid-beta-derived short peptides

28 September 2017

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Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources

28 September 2017

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Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses

28 September 2017

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The non-amyloidogenic pathway: structure and function of alpha-secretases

28 September 2017

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Reactive oxygen species and the mitochondrial signaling pathway of cell death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

28 September 2017

Free radicals and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Beta-secretase activity increases with aging in human, monkey, and mouse brain.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Amyloidosis and Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Protein oxidation in aging and age-related diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

The amyloidogenic pathway of amyloid precursor protein (APP) is independent of its cleavage by caspases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Peroxisomes as a source of reactive oxygen species and nitric oxide signal molecules in plant cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Ginkgo biloba leaf extract: review of biological actions and clinical applications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Effect of oxidative DNA damage in promoter elements on transcription factor binding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Cellular defenses against damage from reactive oxygen species

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Free radicals in biology: oxidative stress and the effects of ionizing radiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Aβ and tau toxicities in Alzheimer's are linked via oxidative stress-induced p38 activation: protective role of vitamin E

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Tobacco smoke: involvement of reactive oxygen species and stable free radicals in mechanisms of oxidative damage, carcinogenesis and synergistic effects with other respirable particles.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Production of reactive oxygen species by mitochondria: central role of complex III.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620382

Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease

31 May 2018

1 reference

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

Reactive oxygen species formation in the transition to hypoxia in skeletal muscle

21 January 2018

1 reference

Metabolomic study of lipids in serum for biomarker discovery in Alzheimer's disease using direct infusion mass spectrometry.

21 January 2018

1 reference

Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation

21 January 2018

1 reference

Evidence for participation of aluminum in neurofibrillary tangle formation and growth in Alzheimer's disease.

21 January 2018

1 reference

Investigation on positive correlation of increased brain iron deposition with cognitive impairment in Alzheimer disease by using quantitative MR R2' mapping

21 January 2018

1 reference

Elucidation of the mechanism of selenoprotein glutathione peroxidase (GPx)-catalyzed hydrogen peroxide reduction by two glutathione molecules: a density functional study

21 January 2018

1 reference

Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases

21 January 2018

1 reference

Lipid peroxidation and antioxidant enzyme activities in vascular and Alzheimer dementias.

21 January 2018

1 reference

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease

21 January 2018

1 reference

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

21 January 2018

1 reference

Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers.

21 January 2018

1 reference

Rutin activates the MAPK pathway and BDNF gene expression on beta-amyloid induced neurotoxicity in rats.

21 January 2018

1 reference

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

21 January 2018

1 reference

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.

21 January 2018

1 reference

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway.

21 January 2018

1 reference

Overactivation of calcineurin induced by amyloid-beta and prion proteins

21 January 2018

1 reference

The effect of DNA damage on the formation of protein/DNA complexes

21 January 2018

1 reference

Epigenetic regulation of BACE1 in Alzheimer's disease patients and in transgenic mice.

21 January 2018

1 reference

Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease.

21 January 2018

1 reference

Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress

21 January 2018

1 reference

Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats

21 January 2018

1 reference

Antioxidant potential of vitamins A, E and C in modulating oxidative stress in rat brain

21 January 2018

1 reference

Vitamin E paradox in Alzheimer's disease: it does not prevent loss of cognition and may even be detrimental.

21 January 2018

1 reference

Efficacy and tolerability of Ginkgo biloba extract EGb 761 by type of dementia: analyses of a randomised controlled trial.

21 January 2018

1 reference

Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.

21 January 2018

1 reference

Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators.

21 January 2018

1 reference

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26543520

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2015/604658

1 reference

1 reference

1 reference

PubMed publication ID

26543520

1 reference