An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts (Q26772895)

2

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Jee Yun Han

3

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Seoyeon Min

4

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Jinjoo Kang

5

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Ahra Lee

6

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Jee Young Kwon

7

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Charles Lee

8

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Hansoo Park

The Cancer Genome Atlas Pan-Cancer analysis project

9

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language of work or name

English

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publication date

February 2016

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1 February 2016

6 references

21 March 2019

3 April 2019

25 June 2019

19 September 2019

13 November 2020

10 December 2020

6 references

21 March 2019

3 April 2019

25 June 2019

19 September 2019

13 November 2020

10 December 2020

39

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issue

2

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page(s)

77-86

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cites work

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High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

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Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer

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XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer

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The extent of inflammatory infiltration in primary cancer tissues is associated with lymphomagenesis in immunodeficient mice

28 September 2017

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Patient-derived xenograft models for pancreatic adenocarcinoma demonstrate retention of tumor morphology through incorporation of murine stromal elements

28 September 2017

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Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma

28 September 2017

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Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.

28 September 2017

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Lessons from patient-derived xenografts for better in vitro modeling of human cancer

28 September 2017

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Patient-derived xenograft models: an emerging platform for translational cancer research

28 September 2017

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Advances in patient-derived tumor xenografts: from target identification to predicting clinical response rates in oncology

28 September 2017

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High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development

28 September 2017

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28 September 2017

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Patient-derived xenografts, the cancer stem cell paradigm, and cancer pathobiology in the 21st century

28 September 2017

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A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models

28 September 2017

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Patient-derived breast tumor xenografts facilitating personalized cancer therapy

28 September 2017

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Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ.

28 September 2017

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28 September 2017

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The promise of patient-derived xenografts: the best laid plans of mice and men

28 September 2017

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Human solid tumor xenografts in immunodeficient mice are vulnerable to lymphomagenesis associated with Epstein-Barr virus

28 September 2017

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Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma

28 September 2017

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The APL paradigm and the "co-clinical trial" project

28 September 2017

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Adjuvant trastuzumab in HER2-positive breast cancer

28 September 2017

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Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial

28 September 2017

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Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer.

28 September 2017

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A pilot clinical study of treatment guided by personalized tumorgrafts in patients with advanced cancer

28 September 2017

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Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme

28 September 2017

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Clinical Implications of the Cancer Genome

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31 May 2018

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Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2Rγnull Immunodeficient Mice.

28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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Characterization of Lymphomas Developing in Immunodeficient Mice Implanted With Primary Human Non–Small Cell Lung Cancer

28 November 2018

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Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.

28 November 2018

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Establishment and characterization of a panel of human uveal melanoma xenografts derived from primary and/or metastatic tumors.

28 November 2018

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28 November 2018

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The tumor microenvironment controls drug sensitivity

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