Amyloid-β Receptors: The Good, the Bad, and the Prion Protein (Q26771532)

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Amyloid-β Receptors: The Good, the Bad, and the Prion Protein (English)

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cell surface receptor

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biomedical investigative technique

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Glutamate ionotropic receptor AMPA type subunit 4

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Glutamate ionotropic receptor NMDA type subunit 2B

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Glutamate ionotropic receptor NMDA type subunit 2A

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amyloid-beta binding

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26 August 2020

Heledd Jarosz-Griffiths

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Nigel Mark Hooper

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author name string

Elizabeth Noble

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Jo V Rushworth

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Journal of Biological Chemistry

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12 February 2016

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26 August 2020

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published in

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issue

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EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.

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Functional and physical interactions between formyl-peptide-receptors and scavenger receptor MARCO and their involvement in amyloid beta 1-42-induced signal transduction in glial cells

28 September 2017

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Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption

28 September 2017

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Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains.

28 September 2017

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Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease.

28 September 2017

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Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

28 September 2017

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Structural classification of toxic amyloid oligomers

28 September 2017

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Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.

28 September 2017

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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Solution state characterization of amyloid beta-derived diffusible ligands

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-beta peptides via p75NTR/PLAIDD.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Signalosomes in the brain: relevance in the development of certain neuropathologies such as Alzheimer’s disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

The Synaptic Protein Neuroligin-1 Interacts with the Amyloid β-Peptide. Is There a Role in Alzheimer’s Disease?

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Soluble Aβ Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Lipid Rafts: Linking Alzheimer's Amyloid-β Production, Aggregation, and Toxicity at Neuronal Membranes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4751366

In situ Abeta pores in AD brain are cylindrical assembly of Abeta protofilaments

31 May 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.R115.702704

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.R115.702704

Neuroscience. Promiscuous Alzheimer's amyloid: yet another partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.R115.702704

High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.R115.702704

The N-terminal region of the prion protein ectodomain contains a lipid raft targeting determinant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.R115.702704

beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.R115.702704

Antibody against Small Aggregated Peptide Specifically Recognizes Toxic Aβ-42 Oligomers in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.R115.702704

Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.R115.702704

21 January 2018

Identifiers

DOI

10.1074/JBC.R115.702704

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26719327 AND SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26719327 AND SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

26719327

2 references