Epigenetic regulation of insulin-like growth factor axis in hepatocellular carcinoma (Q26766068)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Hend Mohamed El Tayebi

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json

World Journal of Gastroenterology

1 June 2020

language of work or name

English

0 references

publication date

7 March 2016

0 references

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json

1 June 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json

1 June 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

2668-2677

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json

MiR-15a and miR-16-1 cluster functions in human leukemia

1 June 2020

cites work

1 reference

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Intronic microRNA (miRNA)

7 April 2017

1 reference

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Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

7 April 2017

1 reference

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MicroRNA genes are transcribed by RNA polymerase II

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Decreased expression of the mannose 6-phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

DNA methylation patterns and epigenetic memory

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling

7 April 2017

1 reference

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Constitutional relaxation of insulin-like growth factor II gene imprinting associated with Wilms' tumour and gigantism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Interaction of p85 subunit of PI 3‐kinase with insulin and IGF‐1 receptors analysed by using the two‐hybrid system

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

MicroRNAs: genomics, biogenesis, mechanism, and function

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

7 April 2017

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Characterization of insulin receptor substrate 4 in human embryonic kidney 293 cells

21 January 2018

1 reference

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Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

The insulin-like growth factor-binding protein (IGFBP) superfamily

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Genomic structure of the human M6P/IGF2 receptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Insulin-Like Growth Factor-Binding Proteins in Serum and Other Biological Fluids: Regulation and Functions*

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Insulin-like growth factors and their binding proteins: biological actions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Insulin-like growth factor II receptor as a multifunctional binding protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

DNA methylation landscapes: provocative insights from epigenomics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Role of insulin-like growth factors in embryonic and postnatal growth

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

A pleiotropic effect of the single clustered hepatic metastamiRs miR-96-5p and miR-182-5p on insulin-like growth factor II, insulin-like growth factor-1 receptor and insulin-like growth factor-binding protein-3 in hepatocellular carcinoma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Insulin-like growth factor-1 prevents miR-122 production in neighbouring cells to curtail its intercellular transfer to ensure proliferation of human hepatoma cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Repression of miR-17-5p with elevated expression of E2F-1 and c-MYC in non-metastatic hepatocellular carcinoma and enhancement of cell growth upon reversing this expression pattern.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

miR-615-5p is restrictedly expressed in cirrhotic and cancerous liver tissues and its overexpression alleviates the tumorigenic effects in hepatocellular carcinoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

MiR-223 suppresses cell proliferation by targeting IGF-1R.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Epigenetic reprogramming during plant reproduction and seed development.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Clinical and prognostic implications of plasma insulin-like growth factor-1 and vascular endothelial growth factor in patients with hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Targeting insulin-like growth factor axis in hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Differential impacts of insulin-like growth factor-binding protein-3 (IGFBP-3) in epithelial IGF-induced lung cancer development.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Insulin-like growth factor-2 (IGF-2) activates estrogen receptor-α and -β via the IGF-1 and the insulin receptors in breast cancer cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

A novel GSK-3 beta-C/EBP alpha-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Oncogenic role of miR-483-3p at the IGF2/483 locus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

RNA-binding protein insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Allele-specific targeting of hsa-miR-657 to human IGF2R creates a potential mechanism underlying the association of ACAA-insertion/deletion polymorphism with type 2 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Mannose 6-phosphate receptor targeting and its applications in human diseases

28 September 2017

1 reference

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IGF1R signalling and its inhibition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Implications of micro-RNA profiling for cancer diagnosis.

28 September 2017

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The role of the IGF system in cancer growth and metastasis: overview and recent insights

28 September 2017

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Dysregulation of growth factor signaling in human hepatocellular carcinoma.

28 September 2017

1 reference

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The insulin-like growth factor system: IGFs, IGF-binding proteins and IGFBP-proteases

28 September 2017

1 reference

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An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosis

28 September 2017

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Insulin-like growth factors and neoplasia.

28 September 2017

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An evaluation of new criteria for CpG islands in the human genome as gene markers

28 September 2017

1 reference

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The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity.

28 September 2017

1 reference

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A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation

28 September 2017

1 reference

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A possible role for insulin-like growth factor-binding protein-3 autocrine/paracrine loops in controlling hepatocellular carcinoma cell proliferation.

28 September 2017

1 reference

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The IGF axis and hepatocarcinogenesis

28 September 2017

1 reference

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Role of the insulin-like growth factor family in cancer development and progression

28 September 2017

1 reference

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Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

28 September 2017

1 reference

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Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

28 September 2017

1 reference

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Normal growth and development in the absence of hepatic insulin-like growth factor I

28 September 2017

1 reference

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Insulin-like growth factor receptors: recent developments and new methodologies.

28 September 2017

1 reference

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The IRS-1 signaling system

28 September 2017

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Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations

28 September 2017

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The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

28 September 2017

1 reference

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Insulinlike Growth Factor-Binding Proteins

28 September 2017

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Upregulation of the Insulin Receptor and Type I Insulin-Like Growth Factor Receptor Are Early Events in Hepatocarcinogenesis

28 September 2017

1 reference

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Serum insulin-like growth factor I evaluation as a useful tool for predicting the risk of developing hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis: a prospective study.

31 May 2018

1 reference

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Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

31 May 2018

1 reference

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Imprinted M6p/Igf2 receptor is mutated in rat liver tumors

31 May 2018

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Imprinted genes in liver carcinogenesis.

31 May 2018

1 reference

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Insulin receptor substrate 1 overexpression in human hepatocellular carcinoma cells prevents transforming growth factor beta1-induced apoptosis.

31 May 2018

1 reference

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IGF-I is required for normal embryonic growth in mice

31 May 2018

1 reference

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Cooperative transformation of 32D cells by the combined expression of IRS-1 and V-Ha-Ras.

31 May 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Epigenetics and microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Changes in the relative abundance of mRNA transcripts for insulin-like growth factor (IGF-I and IGF-II) ligands and their receptors (IGF-IR/IGF-IIR) in preimplantation bovine embryos derived from different in vitro systems

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Autocrine inhibition of chemotherapy response in human liver tumor cells by insulin-like growth factor-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Loss of parental-specific methylation at the IGF2 locus in human hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Epigenetic modulation of the IGF2/H19 imprinted domain in human embryonic and extra-embryonic compartments and its possible role in fetal growth restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Pro- and mature IGF-II during diet-induced weight loss in obese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

The insulin–like growth factor type–2 receptor gene is imprinted in the mouse but not in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V22.I9.2668

Transcriptional activation of the IGF-II/IGF-1R axis and inhibition of IGFBP-3 by miR-155 in hepatocellular carcinoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Association of circulating insulin-like growth factor 1 with hepatocellular carcinoma: one cross-sectional correlation study.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Loss of imprinting of IGF-II gene in children with acute lymphoblastic leukemia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4777991

Decreased insulin-like growth factor-II/mannose 6-phosphate receptor expression enhances tumorigenicity in JEG-3 cells

28 November 2018

1 reference

12 December 2020

Expression of insulin-like growth factor-II, matrix metalloproteinases, and their tissue inhibitors as predictive markers in the peripheral blood of HCC patients

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12 December 2020

Direct demonstration of rapid insulin-like growth factor II Receptor internalization and recycling in rat adipocytes. Insulin stimulates 125I-insulin-like growth factor II degradation by modulating the IGF-II receptor recycling process

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12 December 2020

Relaxation of imprinting of IGFII gene in juvenile nasopharyngeal angiofibromas

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12 December 2020

The insulin-like growth factors

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12 December 2020

Reactivation of insulin-like growth factor II during hepatocarcinogenesis in transgenic mice suggests a role in malignant growth

1 reference

12 December 2020

Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition

1 reference

12 December 2020

Free and total insulin-like growth factor (IGF)-I, -II, and IGF binding protein-1, -2, and -3 serum levels in patients with active thyroid eye disease

1 reference

12 December 2020

Disturbed synthesis of insulinlike growth factor I and its binding proteins may influence renal function changes in liver cirrhosis

1 reference

12 December 2020

Loss of IGF2 imprinting: a potential marker of colorectal cancer risk

1 reference

12 December 2020

Identifiers

DOI

10.3748/WJG.V22.I9.2668

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

26973407

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26973407 AND SRC:MED&resulttype=core&format=json