Cryptococcus neoformans: Tripping on Acid in the Phagolysosome (Q26765874)

pH signaling in human fungal pathogens: a new target for antifungal strategies

volume

7

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page(s)

164

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cites work

1 reference

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Functional Analysis of Host Factors that Mediate the Intracellular Lifestyle of Cryptococcus neoformans

7 April 2017

1 reference

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Cryptococcal cell morphology affects host cell interactions and pathogenicity

7 April 2017

1 reference

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Fungal cell gigantism during mammalian infection

7 April 2017

1 reference

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Cryptococcus neoformans resides in an acidic phagolysosome of human macrophages

7 April 2017

1 reference

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Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivation

7 April 2017

1 reference

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Enhanced resistance to Cryptococcus neoformans infection induced by chloroquine in a murine model of meningoencephalitis

7 April 2017

1 reference

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Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans

7 April 2017

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Clinical Presentation, Aetiology, and Outcomes of Meningitis in a Setting of High HIV and TB Prevalence

7 April 2017

1 reference

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Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes

28 September 2017

1 reference

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Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion

28 September 2017

1 reference

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The Cryptococcus neoformans alkaline response pathway: identification of a novel rim pathway activator

28 September 2017

1 reference

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Cryptococcus neoformans host adaptation: toward biological evidence of dormancy.

28 September 2017

1 reference

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Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans.

28 September 2017

1 reference

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Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence

28 September 2017

1 reference

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Cryptococcus neoformans induces antimicrobial responses and behaves as a facultative intracellular pathogen in the non mammalian model Galleria mellonella

28 September 2017

1 reference

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The fungal pathogen Cryptococcus neoformans manipulates macrophage phagosome maturation

28 September 2017

1 reference

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Lysosomotropic agents: impact on lysosomal membrane permeabilization and cell death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Temporal kinetics and quantitative analysis of Cryptococcus neoformans nonlytic exocytosis

28 September 2017

1 reference

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The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Tripping on acid: trans-kingdom perspectives on biological acids in immunity and pathogenesis

28 September 2017

1 reference

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Mechanisms of dendritic cell lysosomal killing of Cryptococcus

28 September 2017

1 reference

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Titan cells confer protection from phagocytosis in Cryptococcus neoformans infections

28 September 2017

1 reference

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Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial

28 September 2017

1 reference

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Amoeba provide insight into the origin of virulence in pathogenic fungi

28 September 2017

1 reference

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Chronological aging is associated with biophysical and chemical changes in the capsule of Cryptococcus neoformans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in humans

28 September 2017

1 reference

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Nonlytic exocytosis of Cryptococcus neoformans from macrophages occurs in vivo and is influenced by phagosomal pH.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Phospholipids trigger Cryptococcus neoformans capsular enlargement during interactions with amoebae and macrophages.

28 September 2017

1 reference

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Cathepsins and their involvement in immune responses

28 September 2017

1 reference

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Cryptococcal interactions with the host immune system.

28 September 2017

1 reference

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How human pathogenic fungi sense and adapt to pH: the link to virulence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival

28 September 2017

1 reference

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Lysosomal membrane permeabilization in cell death

28 September 2017

1 reference

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Evidence of a role for monocytes in dissemination and brain invasion by Cryptococcus neoformans

28 September 2017

1 reference

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Cryptococcus neoformans enters the endolysosomal pathway of dendritic cells and is killed by lysosomal components

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Serologic evidence for reactivation of cryptococcosis in solid-organ transplant recipients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Direct cell-to-cell spread of a pathogenic yeast

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

The relative susceptibility of mouse strains to pulmonary Cryptococcus neoformans infection is associated with pleiotropic differences in the immune response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Expulsion of live pathogenic yeast by macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Differential localization of complement component 3 within the capsular matrix of Cryptococcus neoformans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Granuloma and cryptococcosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Cryptococcus neoformans infections at Vancouver Hospital and Health Sciences Centre (1997-2002): epidemiology, microbiology and histopathology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Some factors which affect the initiation of growth of Cryptococcus neoformans.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Mycobacterium's arrest of phagosome maturation in macrophages requires Rab5 activity and accessibility to iron

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Multispecies outbreak of cryptococcosis on southern Vancouver Island, British Columbia.

28 September 2017

1 reference

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Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Intracellular parasitism of macrophages by Cryptococcus neoformans

28 September 2017

1 reference

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Efficacy of recombinant gamma interferon for treatment of systemic cryptococcosis in SCID mice

28 September 2017

1 reference

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Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Chloroquine and the fungal phagosome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756110

Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7.

28 September 2017

1 reference

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Cryptococcus neoformans is a facultative intracellular pathogen in murine pulmonary infection

28 September 2017

1 reference

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Effects of strain variation, serotype, and structural modification on kinetics for activation and binding of C3 to Cryptococcus neoformans.

28 September 2017

1 reference

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Restriction fragment length polymorphism analysis of Cryptococcus neoformans isolates from environmental (pigeon excreta) and clinical sources in New York City

28 September 2017

1 reference

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The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes

28 September 2017

1 reference

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Legionella pneumophila inhibits acidification of its phagosome in human monocytes

28 September 2017

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Cryptococcus neoformans. II. Phagocytosis by human leukocytes

28 September 2017

1 reference

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Growth of Cryptococcus neoformans Within Human Macrophages In Vitro

28 September 2017

1 reference

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In vitro model of penetration and intracellular growth of Listeria monocytogenes in the human enterocyte-like cell line Caco-2.

28 September 2017

1 reference

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A monoclonal antibody to gamma interferon blocks augmentation of natural killer cell activity induced during systemic cryptococcosis

28 September 2017

1 reference

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Dependence of macrophage phagocytic efficacy on antibody concentration

28 September 2017

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Enhancement of antifungal chemotherapy by interferon-gamma in experimental systemic cryptococcosis

31 May 2018

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Conditional lethality of the diprotic weak bases chloroquine and quinacrine against Cryptococcus neoformans

31 May 2018

1 reference

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Contribution of interferon-gamma in protecting mice during pulmonary and disseminated infection with Cryptococcus neoformans

31 May 2018

1 reference

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Isolation of Cryptococcus gattii and Cryptococcus neoformans var. grubii from the flowers and bark of Eucalyptus trees in India.

31 May 2018

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Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes

21 January 2018

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In vivo activity of interferon-gamma in combination with amphotericin B in the treatment of experimental cryptococcosis

21 January 2018

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Granulomatous and cytokine responses to pulmonary Cryptococcus neoformans in two strains of rats.

21 January 2018

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Calcineurin is required for virulence of Cryptococcus neoformans

21 January 2018

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The ABC transporter-encoding gene AFR1 affects the resistance of Cryptococcus neoformans to microglia-mediated antifungal activity by delaying phagosomal maturation

21 January 2018

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The expanding host tree species spectrum of Cryptococcus gattii and Cryptococcus neoformans and their isolations from surrounding soil in India

21 January 2018

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An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia

21 January 2018

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The efficacy of complement-mediated phagocytosis of Cryptococcus neoformans is dependent on the location of C3 in the polysaccharide capsule and involves both direct and indirect C3-mediated interactions.

21 January 2018

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https://api.crossref.org/works/10.3389/FMICB.2016.00164

T cell-dependent activation of macrophages and enhancement of their phagocytic activity in the lungs of mice inoculated with heat-killed Cryptococcus neoformans: involvement of IFN-gamma and its protective effect against cryptococcal infection

21 January 2018

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12 December 2020

Torulosis of the central nervous system; biochemical behavior of the causative organism

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12 December 2020

In vivo interaction between alveolar macrophages and Cryptococcus neoformans

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12 December 2020

Interferon-gamma activates rat alveolar macrophages for anticryptococcal activity

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12 December 2020

Intravascular granuloma induced by intravenous inoculation of Cryptococcus neoformans

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12 December 2020

Cryptococcal meningitis occurring in HIV infected individuals

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Identifiers

DOI

10.3389/FMICB.2016.00164

1 reference

release_27ljmgelnndoziusylefq35thq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/27ljmgelnndoziusylefq35thq

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

PubMed publication ID

26925039

1 reference